Top 12 games similar to Alchemia: Creatio Ex Nihilo

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   Monster Train

   Monster Train is a strategic roguelike deck building game with a twist. Set on a train to hell, you’ll use tactical decision making to defend multiple vertical battlegrounds. With real time competitive multiplayer and endless replayability, Monster Train is always on time.

   Strategy
2. 2
   

   Backpack Hero

   The inventory management roguelike! Collect rare items, organize your backpack, and vanquish your foes!

   AdventureCasualIndie
3. 3
   

   Astrea: Six-Sided Oracles

   Astrea is a DICE-deck-building roguelike that flips the script on deckbuilders by using dice instead of cards and a unique dual “damage” system: Purification vs Corruption. Build a dice pool strong enough to purify Astrea's out-of-control corruption and save the Star System.

   CasualIndieStrategy
4. 4
   

   Astronaut: The Best

   Astronaut: The Best is an occult management adventure where people aren't just numbers: they're screwups. You must run a proper space academy using lies, witchcraft, and/or hard work. Guide cadets through a roguelite web of scandals and challenges, or the government will have you killed.

   AdventureIndieSimulation
5. 5
   

   Hadean Tactics

   Hadean Tactics is a roguelike deckbuilding game fused with autobattler elements to create a unique strategy experience. Use your cards to influence the actions of your units and help your Hero defeat the Six Wings of Hell!

   IndieStrategy
6. 6
   

   Rogue Waters

   Rogue Waters is a Pirate Tactical Turn-Based Rogue-lite. Play as Captain Cutter, commanding your ship and crew through procedurally generated encounters to seek revenge. Recruit, train, and upgrade crew, use powerful sea creatures, and engage in dynamic naval and melee combat to gain the upper hand.

   ActionAdventureRPG
7. 7
   

   Arcanium: Rise of Akhan

   Arcanium is an Open-world, Strategy Card Adventure that merges Roguelite and Deckbuilding genres like never before. Control your party of three heroes, craft your deck, unlock a vast amount of cards and items and save the world of Arzu from corruption!

   AdventureRPGStrategy
8. 8
   

   Gods vs Horrors

   A drafting roguelike focused on synergies and scaling, with short enjoyable runs. Recruit Gods from different mythologies, buff and upgrade them, arrange them in perfect formation, and fight cosmic Horrors in no-RNG autobattler combat to defend the Earth!

   CasualStrategy
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   Throne of Bone

   Draft minions to defeat all who oppose the noble art of necromancy. Wield spells, discover dark relics, and reclaim your castle to unite the land through undeath in this unholy amalgam of roguelike, deckbuilder, and autobattler.

   Strategy
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    Journey to the West

    A challenging rogue-like deck building game about a legendary adventure in the Realm of Divinity. Lead your team, build your unique deck, gather powerful relics and consumables to confront legendary creatures and eventually discover the truth behind the omen of darkness.

    AdventureFree To PlayIndie
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    LONESTAR

    LONESTAR is a strategic Roguelike spaceship deckbuilder. As a bounty hunter, you will capture criminals scattered across the universe. Win the shockwave battle to gain rewards and vacations. Find treasures, customize spaceships, unlock talents, defeat the felons and be a legend!

    AdventureIndieRPG
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    Pirates Outlaws

    Pirates Outlaws is a roguelike card game in which you navigate dangerous seas and challenge their masters. Your expedition will be full of ambushes and will not be easy. Build your deck and combos to become a reputed pirate.

    AdventureCasualIndie