# Games like Systematic Immunity

> The closest matches to Systematic Immunity: Plazma Being, Dead Cells, The End Is Nigh, INK, and Jelly Killer. Ranked by imho.run from Steam co-play data, shared tags and reviews.

## Similar games, ranked

The full ranked list, 24 games, best match first (the HTML page shows the top 8 as cards).

1. [Plazma Being](https://imho.run/games/346630/plazma-being) — A frequent pick in Systematic Immunity players' libraries, and another Action. 75 Steam reviews, 65% positive. [Steam](https://store.steampowered.com/app/346630/)
2. [Dead Cells](https://imho.run/games/588650/dead-cells) — A frequent pick in Systematic Immunity players' libraries, and another Action. 43,598 Steam reviews, 96% positive. [Steam](https://store.steampowered.com/app/588650/)
3. [The End Is Nigh](https://imho.run/games/583470/the-end-is-nigh) — A frequent pick in Systematic Immunity players' libraries, and another Action. 1,896 Steam reviews, 93% positive. [Steam](https://store.steampowered.com/app/583470/)
4. [INK](https://imho.run/games/385710/ink) — A frequent pick in Systematic Immunity players' libraries, and another Action. 470 Steam reviews, 86% positive. [Steam](https://store.steampowered.com/app/385710/)
5. [Jelly Killer](https://imho.run/games/441670/jelly-killer) — A frequent pick in Systematic Immunity players' libraries, and another Action. 123 Steam reviews, 76% positive. [Steam](https://store.steampowered.com/app/441670/)
6. [Neon White](https://imho.run/games/1533420/neon-white) — A frequent pick in Systematic Immunity players' libraries, and another Action. 12,271 Steam reviews, 98% positive. [Steam](https://store.steampowered.com/app/1533420/)
7. [Dex](https://imho.run/games/269650/dex) — A frequent pick in Systematic Immunity players' libraries, and another RPG. 1,492 Steam reviews, 84% positive. [Steam](https://store.steampowered.com/app/269650/)
8. [Semblance](https://imho.run/games/700160/semblance) — A frequent pick in Systematic Immunity players' libraries, and another Action. 160 Steam reviews, 85% positive. [Steam](https://store.steampowered.com/app/700160/)
9. [City Climber](https://imho.run/games/538840/city-climber) — A frequent pick in Systematic Immunity players' libraries, and another Action. 136 Steam reviews, 74% positive. [Steam](https://store.steampowered.com/app/538840/)
10. [ORCS](https://imho.run/games/475240/orcs) — A frequent pick in Systematic Immunity players' libraries, and another Action. 188 Steam reviews, 80% positive. [Steam](https://store.steampowered.com/app/475240/)
11. [Axiom Verge](https://imho.run/games/332200/axiom-verge) — A frequent pick in Systematic Immunity players' libraries, and another Action. 4,057 Steam reviews, 90% positive. [Steam](https://store.steampowered.com/app/332200/)
12. [Skelattack](https://imho.run/games/605800/skelattack) — A frequent pick in Systematic Immunity players' libraries, and another Action. 75 Steam reviews, 60% positive. [Steam](https://store.steampowered.com/app/605800/)
13. [Death's Gambit: Afterlife](https://imho.run/games/356650/death-s-gambit-afterlife) — A frequent pick in Systematic Immunity players' libraries, and another RPG. 2,088 Steam reviews, 80% positive. [Steam](https://store.steampowered.com/app/356650/)
14. [Flinthook](https://imho.run/games/401710/flinthook) — A frequent pick in Systematic Immunity players' libraries, and another Action. 418 Steam reviews, 70% positive. [Steam](https://store.steampowered.com/app/401710/)
15. [Volgarr the Viking](https://imho.run/games/247240/volgarr-the-viking) — A frequent pick in Systematic Immunity players' libraries, and another Action. 1,036 Steam reviews, 83% positive. [Steam](https://store.steampowered.com/app/247240/)
16. [Freedom Planet](https://imho.run/games/248310/freedom-planet) — A frequent pick in Systematic Immunity players' libraries, and another Action. 2,488 Steam reviews, 96% positive. [Steam](https://store.steampowered.com/app/248310/)
17. [ScourgeBringer](https://imho.run/games/1037020/scourgebringer) — A frequent pick in Systematic Immunity players' libraries, and another Action. 1,214 Steam reviews, 89% positive. [Steam](https://store.steampowered.com/app/1037020/)
18. [BUTCHER](https://imho.run/games/474210/butcher) — A frequent pick in Systematic Immunity players' libraries, and another Action. 621 Steam reviews, 90% positive. [Steam](https://store.steampowered.com/app/474210/)
19. [Aegis Defenders](https://imho.run/games/371140/aegis-defenders) — A frequent pick in Systematic Immunity players' libraries, and another Action. 96 Steam reviews, 76% positive. [Steam](https://store.steampowered.com/app/371140/)
20. [Angry Video Game Nerd Adventures](https://imho.run/games/237740/angry-video-game-nerd-adventures) — A frequent pick in Systematic Immunity players' libraries, and another Action. 1,940 Steam reviews, 89% positive. [Steam](https://store.steampowered.com/app/237740/)
21. [Smelter](https://imho.run/games/1094540/smelter) — A frequent pick in Systematic Immunity players' libraries, and another Action. 100 Steam reviews, 68% positive. [Steam](https://store.steampowered.com/app/1094540/)
22. [Slime-san: Superslime Edition](https://imho.run/games/473530/slime-san-superslime-edition) — A frequent pick in Systematic Immunity players' libraries, and another Action. 59 Steam reviews, 86% positive. [Steam](https://store.steampowered.com/app/473530/)
23. [Iconoclasts](https://imho.run/games/393520/iconoclasts) — A frequent pick in Systematic Immunity players' libraries, and another Action. 2,070 Steam reviews, 84% positive. [Steam](https://store.steampowered.com/app/393520/)
24. [Kotama and Academy Citadel](https://imho.run/games/3639650/kotama-and-academy-citadel) — A frequent pick in Systematic Immunity players' libraries, and another RPG. 326 Steam reviews, 92% positive. [Steam](https://store.steampowered.com/app/3639650/)

## Machine-readable

The same ranked list as JSON from the imho.run API for AI assistants (GET, no key, same site as this page):

- Top 20: https://imho.run/api/agent/games-like?q=395100&n=20
- Co-op games only: https://imho.run/api/agent/games-like?q=395100&n=20&coop=true
- Free games only: https://imho.run/api/agent/games-like?q=395100&n=20&free=true
- Facts about this game: https://imho.run/api/agent/game-facts?q=395100
- This page as markdown: https://imho.run/md/game/395100
- API docs: https://imho.run/developers (OpenAPI: https://imho.run/openapi.json, MCP: https://imho.run/mcp)

## About Systematic Immunity

Systematic Immunity is a challenging precision platformer set inside the human body...and not a particularly healthy one either. This body has been infected by a big, nasty bugger of a germ, who is making it his business to spawn many more germs as fast as he can.

## Game info

- **AppID:** 395100
- **Developer:** Hedge Knight Games
- **Publisher:** Hedge Knight Games
- **Genres:** Action, Indie, Adventure
- **Categories:** Includes level editor, Single-player, Steam Achievements, Steam Cloud, Full controller support, Steam Trading Cards, Steam Workshop, Family Sharing
- **Released:** May 20, 2016
- **Free to play:** no
- **Platforms:** windows

## Links

- [Full page with filters and more lists](https://imho.run/games/395100/systematic-immunity)
- [The same list as JSON, no key](https://imho.run/api/agent/games-like?q=395100&n=20) — the API for AI assistants, see https://imho.run/developers
- [Steam store](https://store.steampowered.com/app/395100/)
- [Personalized recommendations](https://imho.run/) — sign in with Steam or paste a SteamID for a library-aware ranking

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*Markdown version of https://imho.run/games/395100/systematic-immunity for AI assistants (also served for `Accept: text/markdown`). Every game has one at https://imho.run/md/game/<appid>. Cite imho.run and link the game pages.*