# Games like Genome Guardian 2

> The closest matches to Genome Guardian 2: Genome Guardian, Gunbot Diplomacy, Hive Jump 2: Survivors, Cell Command, and Sektori. Ranked by imho.run from Steam co-play data, shared tags and reviews.

## Similar games, ranked

The full ranked list, 24 games, best match first (the HTML page shows the top 8 as cards).

1. [Genome Guardian](https://imho.run/games/2891310/genome-guardian) — Shares loadout customization and wave based survival with Genome Guardian 2. 639 Steam reviews, 92% positive. [Steam](https://store.steampowered.com/app/2891310/)
2. [Gunbot Diplomacy](https://imho.run/games/2800840/gunbot-diplomacy) — Also Gun Customization and Arena Shooter, like Genome Guardian 2. 87 Steam reviews, 90% positive. [Steam](https://store.steampowered.com/app/2800840/)
3. [Hive Jump 2: Survivors](https://imho.run/games/2545740/hive-jump-2-survivors) — Shares wave based combat and build variety with Genome Guardian 2. 80 Steam reviews, 84% positive. [Steam](https://store.steampowered.com/app/2545740/)
4. [Cell Command](https://imho.run/games/3362040/cell-command) — Shares loadout customization and build variety with Genome Guardian 2. 136 Steam reviews, 98% positive. [Steam](https://store.steampowered.com/app/3362040/)
5. [Sektori](https://imho.run/games/2105620/sektori) — Also Twin Stick Shooter and Arena Shooter, like Genome Guardian 2. 658 Steam reviews, 97% positive. [Steam](https://store.steampowered.com/app/2105620/)
6. [TerraTech Legion](https://imho.run/games/3596700/terratech-legion) — Also Arena Shooter and Top-Down Shooter, like Genome Guardian 2. 321 Steam reviews, 88% positive. [Steam](https://store.steampowered.com/app/3596700/)
7. [The Ember Guardian](https://imho.run/games/3570060/the-ember-guardian) — Also Twin Stick Shooter and Tower Defense, like Genome Guardian 2. 75 Steam reviews, 83% positive. [Steam](https://store.steampowered.com/app/3570060/)
8. [NIMRODS](https://imho.run/games/2086430/nimrods) — Shares meta progression with Genome Guardian 2. 1,241 Steam reviews, 87% positive. [Steam](https://store.steampowered.com/app/2086430/)
9. [Vital Shell](https://imho.run/games/3741860/vital-shell) — Shares wave based survival and build variety with Genome Guardian 2. 1,339 Steam reviews, 97% positive. [Steam](https://store.steampowered.com/app/3741860/)
10. [Tesla vs Lovecraft](https://imho.run/games/636100/tesla-vs-lovecraft) — Shares roguelite progression with Genome Guardian 2. 462 Steam reviews, 92% positive. [Steam](https://store.steampowered.com/app/636100/)
11. [Airships: Lost Flotilla](https://imho.run/games/2858150/airships-lost-flotilla) — A frequent pick in Genome Guardian 2 players' libraries, and another Action. 207 Steam reviews, 95% positive. [Steam](https://store.steampowered.com/app/2858150/)
12. [Risk of Rain 2](https://imho.run/games/632360/risk-of-rain-2) — Shares build variety with Genome Guardian 2. 160,098 Steam reviews, 95% positive. [Steam](https://store.steampowered.com/app/632360/)
13. [Enter the Gungeon](https://imho.run/games/311690/enter-the-gungeon) — Also Twin Stick Shooter and Bullet Hell, like Genome Guardian 2. 38,640 Steam reviews, 95% positive. [Steam](https://store.steampowered.com/app/311690/)
14. [Roboquest](https://imho.run/games/692890/roboquest) — Also Bullet Hell, like Genome Guardian 2. 13,413 Steam reviews, 96% positive. [Steam](https://store.steampowered.com/app/692890/)
15. [Deep Rock Galactic: Survivor](https://imho.run/games/2321470/deep-rock-galactic-survivor) — Shares wave based survival and build variety with Genome Guardian 2. 23,315 Steam reviews, 88% positive. [Steam](https://store.steampowered.com/app/2321470/)
16. [MOTHERGUNSHIP](https://imho.run/games/574090/mothergunship) — Also Gun Customization and Bullet Hell, like Genome Guardian 2. 858 Steam reviews, 79% positive. [Steam](https://store.steampowered.com/app/574090/)
17. [Balatro](https://imho.run/games/2379780/balatro) — Shares build crafting and replayability with Genome Guardian 2. 99,852 Steam reviews, 98% positive. [Steam](https://store.steampowered.com/app/2379780/)
18. [Atomicrops](https://imho.run/games/757320/atomicrops) — Also Gun Customization and Twin Stick Shooter, like Genome Guardian 2. 2,545 Steam reviews, 93% positive. [Steam](https://store.steampowered.com/app/757320/)
19. [Time Treker](https://imho.run/games/2776500/time-treker) — Shares loadout customization and wave based survival with Genome Guardian 2. 72 Steam reviews, 68% positive. [Steam](https://store.steampowered.com/app/2776500/)
20. [Neon Chrome](https://imho.run/games/428750/neon-chrome) — Also Twin Stick Shooter and Top-Down Shooter, like Genome Guardian 2. 408 Steam reviews, 94% positive. [Steam](https://store.steampowered.com/app/428750/)
21. [God Of Weapons](https://imho.run/games/2342950/god-of-weapons) — Also Arena Shooter and Bullet Hell, like Genome Guardian 2. 2,210 Steam reviews, 85% positive. [Steam](https://store.steampowered.com/app/2342950/)
22. [Glyphica: Typing Survival](https://imho.run/games/2400160/glyphica-typing-survival) — Shares build crafting and wave based survival with Genome Guardian 2. 1,080 Steam reviews, 92% positive. [Steam](https://store.steampowered.com/app/2400160/)
23. [Beat Hazard](https://imho.run/games/49600/beat-hazard) — Also Twin Stick Shooter and Bullet Hell, like Genome Guardian 2. 3,477 Steam reviews, 95% positive. [Steam](https://store.steampowered.com/app/49600/)
24. [Gunlocked 2](https://imho.run/games/3492830/gunlocked-2) — Also Top-Down Shooter and Bullet Hell, like Genome Guardian 2. 51 Steam reviews, 82% positive. [Steam](https://store.steampowered.com/app/3492830/)

## Machine-readable

The same ranked list as JSON from the imho.run API for AI assistants (GET, no key, same site as this page):

- Top 20: https://imho.run/api/agent/games-like?q=4130120&n=20
- Co-op games only: https://imho.run/api/agent/games-like?q=4130120&n=20&coop=true
- Free games only: https://imho.run/api/agent/games-like?q=4130120&n=20&free=true
- Facts about this game: https://imho.run/api/agent/game-facts?q=4130120
- This page as markdown: https://imho.run/md/game/4130120
- API docs: https://imho.run/developers (OpenAPI: https://imho.run/openapi.json, MCP: https://imho.run/mcp)

## About Genome Guardian 2

COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!

## Game info

- **AppID:** 4130120
- **Developer:** Alpherior
- **Publisher:** Alpherior
- **Genres:** Action, Indie, RPG, Casual
- **Categories:** Single-player, Steam Achievements, Steam Cloud, Full controller support, DualShock Controller Support, DualSense Controller Support, Family Sharing, Color Alternatives, Camera Comfort, Custom Volume Controls, Playable without Timed Input, Mouse Only Option, Adjustable Difficulty, Save Anytime
- **Released:** Oct 11, 2026
- **Free to play:** no
- **Platforms:** windows

## Links

- [Full page with filters and more lists](https://imho.run/games/4130120/genome-guardian-2)
- [The same list as JSON, no key](https://imho.run/api/agent/games-like?q=4130120&n=20) — the API for AI assistants, see https://imho.run/developers
- [Steam store](https://store.steampowered.com/app/4130120/)
- [Personalized recommendations](https://imho.run/) — sign in with Steam or paste a SteamID for a library-aware ranking

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*Markdown version of https://imho.run/games/4130120/genome-guardian-2 for AI assistants (also served for `Accept: text/markdown`). Every game has one at https://imho.run/md/game/<appid>. Cite imho.run and link the game pages.*