Single-player games like Pathogenesis: Overcome
Below are 10 single-player Steam games similar to Pathogenesis: Overcome, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Pathogenesis: Overcome page.
Ranked picks
- 1

The Azmodeus Project
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares Action with Pathogenesis: Overcome.
Venture to the Azmodeus Island and try to survive in a post apocalyptic world riddled with zombies and other dangers.
- 2

Zombie Protocol
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares Action and RPG with Pathogenesis: Overcome.
Zombie Protocol is a hardcore isometric survival sim. Stay alive while caring for your baby—feed, protect, and keep quiet, because zombies react to every sound. Craft gear, drive when you must, and explore procedurally generated cities where every run is unique.
- 3

Red Soil
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares RPG and Early Access with Pathogenesis: Overcome.
Survive the heat and the undead in this isometric horror game set in the Australian outback. Manage stamina, hydration, hunger, and fatigue while exploring random maps, leveling up, crafting gear, and to fight in the heat of the day or the darkness of night.
- 4

Walking Zombie 2
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares Action and RPG with Pathogenesis: Overcome.
Zombie singleplayer shooter in modern polygon graphics with rich RPG elements.
- 5

Zomdied
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares Action and RPG with Pathogenesis: Overcome.
A hardcore top-down zombie survival sandbox RPG. Scavenge for supplies, craft essential gear, and fight to survive against an ever-evolving horde that grows stronger and more dangerous the longer you last. Finding it too easy to survive the turning? Make it a challenge worthy of your skill.
- 6

Aksun
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares Action and RPG with Pathogenesis: Overcome.
A hack & slash roguelite rooted in Korean shamanism. Descend to the dark shadows of Aksun, chain hundreds of elemental artifacts and abilities into devastating reactions, and break the cursed cycle.
- 7

Rest In Pieces
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares Action and RPG with Pathogenesis: Overcome.
Welcome to Rest In Pieces , control AI driven Agents in the battle against hordes of demons. Show your skills on the battlefield and on Global Leaderboards in this singleplayer Horror Survival VR Shooter.
- 8

Futurocco 2121
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares Action and RPG with Pathogenesis: Overcome.
Futurocco 2121 is a sci-fi action thriller set in a dystopian Moroccan-punk Casablanca. Master stealth, fluid parkour, and tactical combat to outsmart a ruthless megacorporation in a hostile urban playground.
- 9

Project Zomboid
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares RPG and Early Access with Pathogenesis: Overcome.
Project Zomboid is the ultimate in zombie survival. Alone or in MP: you loot, build, craft, fight, farm and fish in a struggle to survive. A hardcore RPG skillset, a vast map, massively customisable sandbox and a cute tutorial raccoon await the unwary. So how will you die? All it takes is a bite..
- 10

Practical Shooting Simulator
Single-player alternative to Pathogenesis: Overcome — playable solo, no multiplayer required. Shares Early Access with Pathogenesis: Overcome.
Practical Shooting Simulator contains a wide variety of features for creating stages, exercise planning, and testing abilities in practical shooting. Not just a game, but a unique tool for organizers, competitors, and all enthusiasts of Practical shooting.