Single-player games like Slime Pandemic TD
Below are 9 single-player Steam games similar to Slime Pandemic TD, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Slime Pandemic TD page.
Ranked picks
- 1

Botanical TD
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.
Defend against evil snails with a variety of plants in this Tower Defense while YOU have to make constant decisions how your enemies get stronger.
- 2

SUPRACORE
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.
SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!
- 3

Zomboard
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.
Zomboard is a post-apocalyptic colony sim and base defense game. Start with a few survivors, build your settlement, and fortify defenses to survive overwhelming zombie hordes.
- 4

Defensurvivor
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.
DEFENSURVIVOR is a strategy game where you build obstacles and place and move units to block zombies. There are various units with unique characteristics and powerful high-level units that can be obtained through combination. Use randomly given units to survive until the end!
- 5

Mindustry
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.
An open-ended factory management game with RTS and tower defense elements.
- 6

Broken Universe - Tower Defense
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.
Get ready to rethink all your defense strategies! Build barricades to stop monsters, or lure them into a maze and attack. A variety of stages that change each time depending on how you play them.
- 7

Minimalist Tower Defense
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.
Collect resources and establish a defense line before dark And then Facing countless enemies
- 8

Creeper World 3: Arc Eternal
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.
Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.
- 9

Kingdom Run VR
Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required.
Kingdom Run VR is an action-packed fitness game; explore trapped tombs, avoid dangers, collect gems and eliminate enemies!