IMHO.

Single-player games like Slime Pandemic TD

Below are 9 single-player Steam games similar to Slime Pandemic TD, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Slime Pandemic TD page.

Ranked picks

  1. 1
    Botanical TD — Steam game cover

    Botanical TD

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Defend against evil snails with a variety of plants in this Tower Defense while YOU have to make constant decisions how your enemies get stronger.

    2022StrategyIndieCasual3.99 USDSingle-playerSimilar games →
  2. 2
    SUPRACORE — Steam game cover

    SUPRACORE

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

    2023StrategyIndie4.99 USDSingle-playerSimilar games →
  3. 3
    Defensurvivor — Steam game cover

    Defensurvivor

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    DEFENSURVIVOR is a strategy game where you build obstacles and place and move units to block zombies. There are various units with unique characteristics and powerful high-level units that can be obtained through combination. Use randomly given units to survive until the end!

    2024StrategyIndieSimulation10.99 USDDeck PlayableSingle-playerSimilar games →
  4. 4
    Mindustry — Steam game cover

    Mindustry

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    An open-ended factory management game with RTS and tower defense elements.

    2019Strategy9.99 USDDeck PlayableSingle-playerSimilar games →
  5. 5
    Broken Universe - Tower Defense — Steam game cover

    Broken Universe - Tower Defense

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Get ready to rethink all your defense strategies! Build barricades to stop monsters, or lure them into a maze and attack. A variety of stages that change each time depending on how you play them.

    2023StrategyIndieCasual9.99 USDDeck PlayableSingle-playerSimilar games →
  6. 6
    Minimalist Tower Defense — Steam game cover

    Minimalist Tower Defense

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Collect resources and establish a defense line before dark And then Facing countless enemies

    2024StrategyIndieCasual4.99 USDDeck PlayableSingle-playerSimilar games →
  7. 7
    Creeper World 3: Arc Eternal — Steam game cover

    Creeper World 3: Arc Eternal

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

    2014StrategyIndieSimulation14.99 USDDeck PlayableSingle-playerSimilar games →
  8. 8
    Nordhold — Steam game cover

    Nordhold

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Enemies are coming! Every decision matters: build your city, grow the economy, and prepare for enemy waves. Strengthen your defenses, adapt your strategy, and unleash your hero’s full potential. This unique Tower Defense will test your skills – are you worthy to claim a place at Valhalla?

    2025StrategyIndie19.99 USDDeck PlayableSingle-playerSimilar games →
  9. 9
    Kingdom Run VR — Steam game cover

    Kingdom Run VR

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required.

    Kingdom Run VR is an action-packed fitness game; explore trapped tombs, avoid dangers, collect gems and eliminate enemies!

    2023ActionIndieAdventure3.99 USDSingle-playerSimilar games →