IMHO.

Single-player games like Slime Pandemic TD

Below are 9 single-player Steam games similar to Slime Pandemic TD, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Slime Pandemic TD page.

Ranked picks

  1. 1
    Botanical TD — Steam game cover

    Botanical TD

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Defend against evil snails with a variety of plants in this Tower Defense while YOU have to make constant decisions how your enemies get stronger.

    2022StrategyIndieCasual3.99 USDSingle-playerSimilar games →
  2. 2
    SUPRACORE — Steam game cover

    SUPRACORE

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    SUPRACORE is a roguelike base building game. Build your base, upgrade it and defend against ongoing waves of enemies to gather more resources and expand your Core!

    2023StrategyIndie4.99 USDSingle-playerSimilar games →
  3. 3
    Zomboard — Steam game cover

    Zomboard

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Zomboard is a post-apocalyptic colony sim and base defense game. Start with a few survivors, build your settlement, and fortify defenses to survive overwhelming zombie hordes.

    2025StrategyIndieSimulation7.99 USDSingle-playerSimilar games →
  4. 4
    Defensurvivor — Steam game cover

    Defensurvivor

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    DEFENSURVIVOR is a strategy game where you build obstacles and place and move units to block zombies. There are various units with unique characteristics and powerful high-level units that can be obtained through combination. Use randomly given units to survive until the end!

    2024StrategyIndieSimulation10.99 USDDeck PlayableSingle-playerSimilar games →
  5. 5
    Mindustry — Steam game cover

    Mindustry

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    An open-ended factory management game with RTS and tower defense elements.

    2019Strategy9.99 USDDeck PlayableSingle-playerSimilar games →
  6. 6
    Broken Universe - Tower Defense — Steam game cover

    Broken Universe - Tower Defense

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Get ready to rethink all your defense strategies! Build barricades to stop monsters, or lure them into a maze and attack. A variety of stages that change each time depending on how you play them.

    2023StrategyIndieCasual9.99 USDDeck PlayableSingle-playerSimilar games →
  7. 7
    Minimalist Tower Defense — Steam game cover

    Minimalist Tower Defense

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Collect resources and establish a defense line before dark And then Facing countless enemies

    2024StrategyIndieCasual4.99 USDDeck PlayableSingle-playerSimilar games →
  8. 8
    Creeper World 3: Arc Eternal — Steam game cover

    Creeper World 3: Arc Eternal

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required. Shares Strategy with Slime Pandemic TD.

    Creeper World 3 is what happens when cellular automata takes over a strategy simulation. Instead of discrete units that attack your base, a fluid-like substance spreads over the terraformable terrain. Your base, your weapons, your strategy... you must adapt them all.

    2014StrategyIndieSimulation14.99 USDDeck PlayableSingle-playerSimilar games →
  9. 9
    Kingdom Run VR — Steam game cover

    Kingdom Run VR

    Single-player alternative to Slime Pandemic TD — playable solo, no multiplayer required.

    Kingdom Run VR is an action-packed fitness game; explore trapped tombs, avoid dangers, collect gems and eliminate enemies!

    2023ActionIndieAdventure3.99 USDSingle-playerSimilar games →