Single-player games like PHYSARUM: Slime Mold Simulator
Below are 8 single-player Steam games similar to PHYSARUM: Slime Mold Simulator, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like PHYSARUM: Slime Mold Simulator page.
Ranked picks
- 1
Substrate: Emergence
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Grow fluorescent cells that create mesmerizing emergent chaos. Simple mechanics hide deep complexity as cells evolve survival strategies through synergistic interactions. Catalogue successful lines and culture them to develop your own unique biology.
- 2
Sand in a Box
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Sand in a Box is a 'falling sand' game that simulates thermal flow, electricity, radioactive decay, and gravity. Create art, experiment with physics, and craft your own simulation rules with user-friendly mod support!
- 3
Alchemy Laboratory: Simulator
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Dive into a world of creation and discovery, where each element combines to form new ones. Experiment freely in this interactive sandbox. But be careful: every combination has its consequences..
- 4
The Sapling
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Simulation with PHYSARUM: Slime Mold Simulator.
The Sapling is a short simulation game where you design your own plants and animals, and put them in a world together. Or you turn on random mutations, and see what evolution does to your ecosystem!
- 5
4D Games
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
4D Shapes, 4D Chess and 4D Mazes!? Take a deep dive into the world of Four Dimensions, with more control than ever before!
- 6
Gridworld
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger, and compete with other creatures for survival.
- 7
Intelligent Design: An Evolutionary Sandbox
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
A toy ecosystem with fully simulated genetics and evolution. Will you tinker with DNA or sit back, relax, and see if life finds a way?
- 8
Universe Sandbox
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Create & destroy on an unimaginable scale with a realistic physics-based space simulator. Explore the beauty of our universe and the fragility of our planet. Use science to bend the laws of gravity, collide planets, boil away oceans, fire epic space lasers, and customize your universe.