Single-player games like PHYSARUM: Slime Mold Simulator
Below are 8 single-player Steam games similar to PHYSARUM: Slime Mold Simulator, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like PHYSARUM: Slime Mold Simulator page.
Ranked picks
- 1
Substrate: Emergence
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Grow colonies of fluorescent cells that mutate, swarm, and devour each other in a petri dish arena. Propagate a unique biology of your own as you compete against rival labs in a detailed artificial life simulation.
- 2
Terra Logic
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Sculpt planets and landscapes, watch water and climate respond, and compare two versions of the same world. Import heightmaps, draw mountain ranges, and export flat terrain to Minecraft Java. Explore Earth, ancient continents and distant worlds at your own pace.
- 3
Sediment
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
A pixel-physics sandbox. Fifty materials, and every one of them is physics: sand finds its angle, water freezes, lava crusts into stone, gunpowder blows. Build your own materials and worlds, and share them in the Workshop.
- 4
Sand in a Box
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Sand in a Box is a 'falling sand' game that simulates thermal flow, electricity, radioactive decay, and gravity. Create art, experiment with physics, and craft your own simulation rules with user-friendly mod support!
- 5
The Sapling
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Simulation with PHYSARUM: Slime Mold Simulator.
The Sapling is a short simulation game where you design your own plants and animals, and put them in a world together. Or you turn on random mutations, and see what evolution does to your ecosystem!
- 6
Alchemy Laboratory: Simulator
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Dive into a world of creation and discovery, where each element combines to form new ones. Experiment freely in this interactive sandbox. But be careful: every combination has its consequences..
- 7
4D Games
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
4D Shapes, 4D Chess and 4D Mazes!? Take a deep dive into the world of Four Dimensions, with more control than ever before!
- 8
Gridworld
Single-player alternative to PHYSARUM: Slime Mold Simulator — playable solo, no multiplayer required. Shares Indie and Simulation with PHYSARUM: Slime Mold Simulator.
Gridworld is an artificial life and evolution simulator. Watch creatures evolve through natural selection as they learn to find food, avoid danger, and compete with other creatures for survival.