Single-player games like You VS Drugs
Below are 8 single-player Steam games similar to You VS Drugs, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like You VS Drugs page.
Ranked picks
- 1

Tsukisas Arena
Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.
The laboratory you've just joined as an assistant is on the verge of closure...! To save the lab, engage in a slapstick science adventure game (with occasional action elements) with "Prof. Shiika", who is a genius but a social misfit!
- 2

Colony
Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.
A teenage guy is playing cricket with his friends outside a haunted house, and as he strikes a six,the ball travels inside the home.He goes to pick up the ball. During his search, he experienced a horrifying incident with the ghost.
- 3

Dirty Wars: September 11
Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.
Historical indie videogame about the suburbs of the Cold War in South America.
- 4

Wonhon: The Beginning
Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.
A paranormal stealth-action and tactics game about a young Korean girl who was killed in a military conflict and returned from the dead with the ability to turn into a ghost and possess living creatures to exact her revenge.
- 5

The Journey - Episode 1: Whatever This Is
Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Adventure and Casual with You VS Drugs.
The first step that you never knew you needed to take to get to wherever you're wanting to go...
- 6

Zefyr: A Thief's Melody
Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.
In a colorful archipelago, play as a young thief studying at the Guild. Investigate kidnappings, steer clear of roaming pirates or fight them. Sail the ocean on a cute turtle and climb every island. Cure sick animals, and find the truth during this feel-good journey. Made by a dreamer solo dev.
- 7

Oddworld: Soulstorm Enhanced Edition
Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.
Oddworld: Soulstorm is the explosive second game in a brand new Oddworld Quintology that tells the continuing story of Abe and his comrades as they discover further crimes against Mudokonkind and look for the spark that will ignite a revolution.
- 8

Into A Dream
Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Indie and Adventure with You VS Drugs.
You are his last hope. The only one who can rescue him. Delve deep into the dreams of Luke Williams, a man diagnosed with depression, unfold the heartbreaking story of his life and prevent him from... fading away.