IMHO.

Single-player games like You VS Drugs

Below are 8 single-player Steam games similar to You VS Drugs, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like You VS Drugs page.

Ranked picks

  1. 1
    Tsukisas Arena — Steam game cover

    Tsukisas Arena

    Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.

    The laboratory you've just joined as an assistant is on the verge of closure...! To save the lab, engage in a slapstick science adventure game (with occasional action elements) with "Prof. Shiika", who is a genius but a social misfit!

    2023ActionIndieAdventure8.99 USDSingle-playerSimilar games →
  2. 2
    Colony — Steam game cover

    Colony

    Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.

    A teenage guy is playing cricket with his friends outside a haunted house, and as he strikes a six,the ball travels inside the home.He goes to pick up the ball. During his search, he experienced a horrifying incident with the ghost.

    2024ActionIndieAdventure0.99 USDSingle-playerSimilar games →
  3. 3
    Dirty Wars: September 11 — Steam game cover

    Dirty Wars: September 11

    Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.

    Historical indie videogame about the suburbs of the Cold War in South America.

    2023ActionStrategyIndie4.99 USDSingle-playerSimilar games →
  4. 4
    Wonhon: The Beginning — Steam game cover

    Wonhon: The Beginning

    Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.

    A paranormal stealth-action and tactics game about a young Korean girl who was killed in a military conflict and returned from the dead with the ability to turn into a ghost and possess living creatures to exact her revenge.

    2021ActionIndieAdventureFreeSingle-playerSimilar games →
  5. 5
    The Journey - Episode 1: Whatever This Is — Steam game cover

    The Journey - Episode 1: Whatever This Is

    Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Adventure and Casual with You VS Drugs.

    The first step that you never knew you needed to take to get to wherever you're wanting to go...

    2021AdventureSimulationCasual1.99 USDSingle-playerSimilar games →
  6. 6
    Zefyr: A Thief's Melody — Steam game cover

    Zefyr: A Thief's Melody

    Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.

    In a colorful archipelago, play as a young thief studying at the Guild. Investigate kidnappings, steer clear of roaming pirates or fight them. Sail the ocean on a cute turtle and climb every island. Cure sick animals, and find the truth during this feel-good journey. Made by a dreamer solo dev.

    2025ActionIndieAdventure19.99 USDDeck VerifiedSingle-playerSimilar games →
  7. 7
    Oddworld: Soulstorm Enhanced Edition — Steam game cover

    Oddworld: Soulstorm Enhanced Edition

    Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Action and Indie with You VS Drugs.

    Oddworld: Soulstorm is the explosive second game in a brand new Oddworld Quintology that tells the continuing story of Abe and his comrades as they discover further crimes against Mudokonkind and look for the spark that will ignite a revolution.

    2022ActionIndieAdventure39.99 USDDeck PlayableSingle-playerSimilar games →
  8. 8
    Into A Dream — Steam game cover

    Into A Dream

    Single-player alternative to You VS Drugs — playable solo, no multiplayer required. Shares Indie and Adventure with You VS Drugs.

    You are his last hope. The only one who can rescue him. Delve deep into the dreams of Luke Williams, a man diagnosed with depression, unfold the heartbreaking story of his life and prevent him from... fading away.

    2020IndieAdventureCasual11.99 USDSingle-playerSimilar games →