Single-player games like Epi Derick
Below are 8 single-player Steam games similar to Epi Derick, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Epi Derick page.
Ranked picks
- 1

Physician Simulator
Single-player alternative to Epi Derick — playable solo, no multiplayer required. Shares Indie and Simulation with Epi Derick.
A district physician simulator. See patients, review lab results, make diagnoses and write prescriptions. Real doctors say they recognize themselves. Every decision has consequences.
- 2

Dr. Oops!
Single-player alternative to Epi Derick — playable solo, no multiplayer required. Shares Indie and Simulation with Epi Derick.
Diagnose bizarre patients and pay off your debt! A dark comedy medical adventure about an unlicensed doctor working in a shady hospital!
- 3

Pharmacy Store Simulator
Single-player alternative to Epi Derick — playable solo, no multiplayer required. Shares Indie and Simulation with Epi Derick.
Run your own Pharmacy! Sell medicines, advise customers, validate prescriptions, and fulfill them. Start small and expand your business - make it big in the medicine world!
- 4

Doctor Life Simulator
Single-player alternative to Epi Derick — playable solo, no multiplayer required. Shares Indie and Simulation with Epi Derick.
Step into the shoes of a dedicated medical professional in Doctor Life Simulator. Experience the challenges and triumphs of running your own medical practice, from diagnosing complex illnesses to performing life-saving surgeries.
- 5

World Railway
Single-player alternative to Epi Derick — playable solo, no multiplayer required. Shares Indie and Simulation with Epi Derick.
World Railway is a sim management game and you're a conductor reviving an old train. Produce and gather resources in stations via loops, process and manage onboard. A new world unfolds with the wheel's rumble. On your journey, forge bonds and witness the seasons.
- 6

Shahin's Game Cafe : Funny Tycoon
Single-player alternative to Epi Derick — playable solo, no multiplayer required. Shares Simulation with Epi Derick.
Run Your Game Cafe in This Funny, 2D, Pixel Art, Game Cafe Tycoon Manager Simulator, Meet Funny Friends , Make new Customers, Keep old Ones Happy, Make Money , Pay Power Bill & Rent Every day , Buy New Games , Update Old Games , Repair Devices , Keep Business Going, Don't Get Bankrupted!
- 7

Untitled Shop Game
Single-player alternative to Epi Derick — playable solo, no multiplayer required. Shares Simulation with Epi Derick.
Untitled Shop Game is a shop simulator that lets you unleash your artistic side. Dozens of decorations await, and there are no limits to how, what, or where you place items (well, except for placing stuff on the roads). Oh, and one more thing: the game includes a music player with over 50 songs!
- 8

Pharmacy Simulator
Single-player alternative to Epi Derick — playable solo, no multiplayer required. Shares Indie and Simulation with Epi Derick.
Experience a realistic pharmacy management experience with Pharmacy Simulator. Set up your shop, decorate it as you wish, and purchase over a hundred types of medications. Pharmacy Simulator offers you an incredibly realistic pharmacy experience. Prove your skills in a challenging economic system.