Single-player games like Virtual Chemistry Lab
Below are 8 single-player Steam games similar to Virtual Chemistry Lab, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Virtual Chemistry Lab page.
Ranked picks
- 1

AnyCircuit
Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.
Build the digital machines you've always dreamed of! With some patience, love for digital electronics, and a good amount of problem-solving skills, you can create any combinational or sequential circuit in no time, thanks to the user-friendly interface and integrated voxel-editing tools.
- 2

GENIUS AT WORK!
Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.
Test your intelligence and creativity! With Genius At Work you will have your construction area where you can let your imagination fly and carry out your technical projects.
- 3

Universe Sandbox
Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.
Create & destroy on an unimaginable scale with a realistic physics-based space simulator. Explore the beauty of our universe and the fragility of our planet. Use science to bend the laws of gravity, collide planets, boil away oceans, fire epic space lasers, and customize your universe.
- 4

Bartender VR Simulator
Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.
Step behind the virtual bar and flair your way to the stars! Enter the exciting world of bartending and master the art of dazzling mixology in VR.
- 5

Automation - The Car Company Tycoon Game
Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.
Make your dream cars a reality with Automation’s unparalleled car and engine design tools. Gain a competitive edge through smart engineering and business decisions to help you build an automotive empire. Will you become an industry leader, or just a footnote in automotive history?
- 6

Project Chemistry
Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.
Interact with elements and molecules in a way that you have never before! Observe them and make them react with each other in the sandbox mode. Synthesize every molecule in the quest mode. Discover countless macromolecules and the elegancy of chemistry.
- 7

Thrive
Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.
An evolution simulation game. Take control of your species in the environment and edit your species as a whole. Compete with other evolving species for resources on an alien planet.
- 8

Archean
Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.
Gather resources, craft components, build vehicles, and code their logic in a physics-driven engineering sandbox and full scale space sim.