IMHO.

Single-player games like Virtual Chemistry Lab

Below are 8 single-player Steam games similar to Virtual Chemistry Lab, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Virtual Chemistry Lab page.

Ranked picks

  1. 1
    AnyCircuit — Steam game cover

    AnyCircuit

    Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.

    Build the digital machines you've always dreamed of! With some patience, love for digital electronics, and a good amount of problem-solving skills, you can create any combinational or sequential circuit in no time, thanks to the user-friendly interface and integrated voxel-editing tools.

    2024IndieSimulation1.99 USDSingle-playerSimilar games →
  2. 2
    GENIUS AT WORK! — Steam game cover

    GENIUS AT WORK!

    Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.

    Test your intelligence and creativity! With Genius At Work you will have your construction area where you can let your imagination fly and carry out your technical projects.

    2020IndieSimulation2.99 USDSingle-playerSimilar games →
  3. 3
    Universe Sandbox — Steam game cover

    Universe Sandbox

    Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.

    Create & destroy on an unimaginable scale with a realistic physics-based space simulator. Explore the beauty of our universe and the fragility of our planet. Use science to bend the laws of gravity, collide planets, boil away oceans, fire epic space lasers, and customize your universe.

    2015IndieSimulationCasual29.99 USDDeck PlayableSingle-playerSimilar games →
  4. 4
    Bartender VR Simulator — Steam game cover

    Bartender VR Simulator

    Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.

    Step behind the virtual bar and flair your way to the stars! Enter the exciting world of bartending and master the art of dazzling mixology in VR.

    2018IndieSimulationCasual19.99 USDSingle-playerSimilar games →
  5. 5
    Automation - The Car Company Tycoon Game — Steam game cover

    Automation - The Car Company Tycoon Game

    Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.

    Make your dream cars a reality with Automation’s unparalleled car and engine design tools. Gain a competitive edge through smart engineering and business decisions to help you build an automotive empire. Will you become an industry leader, or just a footnote in automotive history?

    2015StrategyIndieSimulation29.99 USDDeck PlayableSingle-playerSimilar games →
  6. 6
    Project Chemistry — Steam game cover

    Project Chemistry

    Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.

    Interact with elements and molecules in a way that you have never before! Observe them and make them react with each other in the sandbox mode. Synthesize every molecule in the quest mode. Discover countless macromolecules and the elegancy of chemistry.

    2021IndieSimulation12.99 USDDeck PlayableSingle-playerSimilar games →
  7. 7
    Thrive — Steam game cover

    Thrive

    Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.

    An evolution simulation game. Take control of your species in the environment and edit your species as a whole. Compete with other evolving species for resources on an alien planet.

    2021IndieSimulationCasual4.99 USDDeck PlayableSingle-playerSimilar games →
  8. 8
    Archean — Steam game cover

    Archean

    Single-player alternative to Virtual Chemistry Lab — playable solo, no multiplayer required. Shares Indie and Simulation with Virtual Chemistry Lab.

    Gather resources, craft components, build vehicles, and code their logic in a physics-driven engineering sandbox and full scale space sim.

    2024IndieSimulationEarly Access19.99 USDSingle-playerSimilar games →