IMHO.

Single-player games like Slime mutation

Below are 8 single-player Steam games similar to Slime mutation, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Slime mutation page.

Ranked picks

  1. 1
    Dungeon and Gravestone — Steam game cover

    Dungeon and Gravestone

    Single-player alternative to Slime mutation — playable solo, no multiplayer required. Shares Action and Indie with Slime mutation.

    Steel yourself in the face of insurmountable opposition as you traverse this ever-changing world in a bid to save it from imminent desolation.

    2021ActionIndieRPG24.99 USDDeck PlayableSingle-playerSimilar games →
  2. 2
    Diary of Lucie — Steam game cover

    Diary of Lucie

    Single-player alternative to Slime mutation — playable solo, no multiplayer required. Shares Action and Indie with Slime mutation.

    Diary of Lucie is action-roguelite game made with RPG Maker. In addition to simply avoiding the enemy's barrage, strategically use the enemy's bullet to make the battle situation advantageous!

    2023ActionStrategyIndie12.99 USDSingle-playerSimilar games →
  3. 3
    Himno - The Silent Melody — Steam game cover

    Himno - The Silent Melody

    Single-player alternative to Slime mutation — playable solo, no multiplayer required. Shares Action and Indie with Slime mutation.

    Himno - The Silent Melody is an atmospheric roguelite action RPG. Explore different interconnected environments, gather materials to create your unique arsenal and build and automate your base.

    2021ActionIndieAdventure11.99 USDDeck VerifiedSingle-playerSimilar games →
  4. 4
    Dungeon Survivors — Steam game cover

    Dungeon Survivors

    Single-player alternative to Slime mutation — playable solo, no multiplayer required. Shares Action and Indie with Slime mutation.

    Dungeon Survivors is a top-down fantasy roguelite where you can use your class abilities to fight off a horde of fantasy monsters. Choose from a variety of abilities and items to create unique builds and survive with 1-4 players.

    2024ActionIndieRPG4.99 USDDeck PlayableSingle-playerSimilar games →
  5. 5
    Devious Dungeon — Steam game cover

    Devious Dungeon

    Single-player alternative to Slime mutation — playable solo, no multiplayer required. Shares Action and Indie with Slime mutation.

    Set in the Dark Ages, Devious Dungeon is a medieval focused action platformer with RPG styled upgrades.

    2019ActionIndieAdventure7.99 USDSingle-playerSimilar games →
  6. 6
    Rogue Legacy — Steam game cover

    Rogue Legacy

    Single-player alternative to Slime mutation — playable solo, no multiplayer required. Shares Action and Indie with Slime mutation.

    Rogue Legacy is a genealogical rogue-"LITE" where anyone can be a hero. Each time you die, your child will succeed you. Every child is unique. One child might be colorblind, another might be a dwarf with vertigo. But that's OK, because no one is perfect, and you don't have to be to succeed.

    2013ActionIndieAdventure14.99 USDDeck VerifiedSingle-playerSimilar games →
  7. 7
    Dungeon Souls — Steam game cover

    Dungeon Souls

    Single-player alternative to Slime mutation — playable solo, no multiplayer required. Shares Action and Indie with Slime mutation.

    Dungeon Souls is an action-adventure roguelike dungeon crawler which draws heavy inspiration from Nuclear Throne, Risk of Rain, and Overture. Explore vast procedurally generated dungeons, collect loot, and slay hordes of challenging enemies!

    2016ActionIndieAdventure12.99 USDDeck PlayableSingle-playerSimilar games →
  8. 8
    Legend of Dungeon — Steam game cover

    Legend of Dungeon

    Single-player alternative to Slime mutation — playable solo, no multiplayer required. Shares Action and Indie with Slime mutation.

    Legend of Dungeon is a randomly generated action RPG Beat'em'up with heavy Rogue-like elements, striking visuals, and dynamic music.

    2013ActionIndieRPG9.99 USDDeck PlayableSingle-playerSimilar games →