Single-player games like Defenders of the Omniverse
Below are 8 single-player Steam games similar to Defenders of the Omniverse, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Defenders of the Omniverse page.
Ranked picks
- 1

X-Mutation
Single-player alternative to Defenders of the Omniverse — playable solo, no multiplayer required. Shares Action and Indie with Defenders of the Omniverse.
Survive thousands of monsters in X-Mutation, a hardcore 3D top-down rogue-lite action game. Mutate your body into diverse weapons, choose from hundreds of mutations, and uniquely upgrade to craft your personal combat style!
- 2

Necromancer's Revenge
Single-player alternative to Defenders of the Omniverse — playable solo, no multiplayer required. Shares Action and Indie with Defenders of the Omniverse.
Summon the Dark Lord for revenge! This game combines survival and roguelite elements, where you summon monsters and place totems to defeat monsters and take down the Dark Lord!
- 3

Skybreakers
Single-player alternative to Defenders of the Omniverse — playable solo, no multiplayer required. Shares Action and Indie with Defenders of the Omniverse.
Skybreakers is an action roguelike thriller. Choose from various characters, arm yourself with a vast array of weapons, and create your own unique build by combining artifacts, random talents, abilities, and bonds. Plunge into exhilarating combat and use unique abilities to defeat the evil.
- 4

Slime 3K: Rise Against Despot
Single-player alternative to Defenders of the Omniverse — playable solo, no multiplayer required. Shares Action and Indie with Defenders of the Omniverse.
Welcome to Slime 3K, an unhinged roguelite bullet-heaven set in the Despot’s Game universe! Build a deck of crazy weapons, grow stronger and devour hordes of pink puny humans as a murderous jelly blob on a warpath of death, violence and pretzels.
- 5

X Invader
Single-player alternative to Defenders of the Omniverse — playable solo, no multiplayer required. Shares Action and Indie with Defenders of the Omniverse.
X Invader is an action roguelite where you hack into big corporations' servers. Use add-ons from fellow hackers to defeat monsters. Powerful, cute bosses guard these servers!
- 6

Brotato
Single-player alternative to Defenders of the Omniverse — playable solo, no multiplayer required. Shares Action and Indie with Defenders of the Omniverse.
Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.
- 7

Elemental Survivors
Single-player alternative to Defenders of the Omniverse — playable solo, no multiplayer required. Shares Action and Indie with Defenders of the Omniverse.
Grind, die, upgrade, repeat in this auto-attacking roguelite/RPG! Transform into an enemy-blender with your fave attacks made devastating with equipment, party members, and elemental evolutions. Survive to earn gems to unlock areas, permanent upgrades, characters, and god-like summons.
- 8

Larva Mortus
Single-player alternative to Defenders of the Omniverse — playable solo, no multiplayer required. Shares Action and Indie with Defenders of the Omniverse.
Larva Mortus is a fast-paced hack and slash top-down shooter. As an agent specializing in exorcism, you are tasked to hunt monsters of the supernatural in a dark, ominous, and randomly generated atmosphere full of undead, terrifying and demonic nightmares.