Single-player games like Prion Virus
Below are 8 single-player Steam games similar to Prion Virus, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Prion Virus page.
Ranked picks
- 1
LandFall Survival
Single-player alternative to Prion Virus — playable solo, no multiplayer required. Shares Action and Indie with Prion Virus.
Landfall is a thrilling low-poly co-op dungeon crawler and extraction game. Build and upgrade your base, trade with vendors, and team up to explore diverse maps, complete quests, gather loot, and defeat bosses. Gear up, survive, and thrive together in this unique low-poly PvE adventure.
- 2
2022生存指南 2022 SURVIVAL GUIDE
Single-player alternative to Prion Virus — playable solo, no multiplayer required. Shares Action and Indie with Prion Virus.
1.Survival plot puzzle video game 2.Linear game with complete and rich plot 3.Player can choose three different game ways: sneaking, attacking and outwitting
- 3
The Game of Annie 安妮的游戏
Single-player alternative to Prion Virus — playable solo, no multiplayer required. Shares Action and Indie with Prion Virus.
Hi,This is a third person action shooter game. Support for custom character size, support for costume change, use guns and bows for long-distance combat, can also use cold weapons for melee combat, with some training elements. Enemies include monsters and humans.
- 4
Heaven Dust 2
Single-player alternative to Prion Virus — playable solo, no multiplayer required. Shares Action and Indie with Prion Virus.
Deep inside a research base, waking up from a cryogenic pod, you find yourself trapped in a living hell, surrounded by zombies. Heaven Dust 2 is a love letter to classic survival horror games featuring exploration, action, puzzles, and resource management.
- 5
The Last of Us™ Part I
Single-player alternative to Prion Virus — playable solo, no multiplayer required. Shares Action and Adventure with Prion Virus.
Discover the award-winning game that inspired the critically acclaimed television show. Guide Joel and Ellie through a post-apocalyptic America, and encounter unforgettable allies and enemies in The Last of Us™.
- 6
Alien Shooter 2 - New Era
Single-player alternative to Prion Virus — playable solo, no multiplayer required. Shares Action and Indie with Prion Virus.
A desert, an abandoned city, cramped underground corridors of MAGMAs research centers, and for hundreds of kilometers around there is only darkness and thousands of monsters coming from all sides. You have only two options - to achieve your goal or die.
- 7
Zombie Apocalypse Survival Simulator
Single-player alternative to Prion Virus — playable solo, no multiplayer required. Shares Indie and Adventure with Prion Virus.
From the creators that brought you The Test Trilogy & many other experiences, comes Zombie Apocalypse Survival Simulator. Will you survive in the new world? Or will you become just another victim to looters, bandits, or worst of all... The Voracious Dead. There's only one way to find out...
- 8
The Last of Waifus
Single-player alternative to Prion Virus — playable solo, no multiplayer required. Shares Action and Adventure with Prion Virus.
You are playing as the last Waifu clearing out the fallen city from Infected whose only target is you.