IMHO.

Games like STEM Defense

If STEM Defense is your kind of game, the closest matches are Terrorformer TD, Deep Among the Swarm and Landnama — picked from the ranked list below. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.

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About STEM Defense: Engage in epic battles against microscopic foes in 'STEM Defense', a strategic tower defense adventure set on a hex-grid. Harness the immune system's power, BUILD your defenses and fend off waves of pathogens, unlock potent cells and upgrades, and evolve your defenses for a grand survival showdown!

2024StrategyIndie9.99 USDWindows · macOSby NoOneGames
STEM Defense — Steam game cover

Players who liked STEM Defense also play

Steam players who put hours into STEM Defense also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.

  1. Terrorformer TD

    WHY THIS

    Top pick for STEM Defense fans by collaborative filtering across millions of Steam libraries. Shares Strategy with STEM Defense.

    Terrorformer TD is a tower defense roguelite with a procedurally generated map that YOU shape! Raise or lower tiles, divert enemy paths and funnel monsters into perfectly designed killzones. Randomly drawn cards result in plenty of run variety, as you seek to survive endless waves of enemies.

    2024Strategy11.99 USDDeck PlayableSteam ↗
  2. Deep Among the Swarm

    WHY THIS

    Second-strongest match for STEM Defense fans by collaborative filtering across millions of Steam libraries. Shares Strategy with STEM Defense.

    Deep Among the Swarm is a challenging survival RTS roguelite about surviving against thousands of enemies. Drill ever deeper underground while fighting the endless onslaught of the Swarm. Can you save humanity?

    2024Strategy8.99 USDDeck PlayableSteam ↗
  3. Landnama

    WHY THIS

    Third-strongest match for STEM Defense fans by collaborative filtering across millions of Steam libraries. Shares Strategy with STEM Defense.

    Face the judgment of winter’s deadly toll as you lead the first Viking clans to settle Iceland in this non-violent, rogue-lite survival base builder.

    2023Strategy13.99 USDDeck VerifiedSteam ↗
  4. Tower Dominion

    WHY THIS

    Ranked #4 for STEM Defense fans by collaborative filtering across millions of Steam libraries. Shares Strategy with STEM Defense.

    Build and design the terrain while defending your stronghold against alien invasion in this unique Roguelike tower defense. Choose from 30 heroes, survive enemy waves, and upgrade a variety of destructive towers to hold the line!

    2025Strategy17.49 USDDeck PlayableSteam ↗
  5. Rogue Tower

    WHY THIS

    Ranked #5 for STEM Defense fans by collaborative filtering across millions of Steam libraries. Shares Strategy with STEM Defense.

    Rogue Tower is a tower defense game with roguelike elements and a continuously expanding path which you can influence. Unlock, build, upgrade, expand, defend.

    2022StrategyCasual14.99 USDDeck PlayableSteam ↗
  6. Kingdom: New Lands

    WHY THIS

    Ranked #6 for STEM Defense fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with STEM Defense.

    Kingdom: New Lands builds upon the award-winning gameplay and mystery of Kingdom by introducing an abundance of new content to the IGF-nominated title while maintaining the simplicity and depth that legions of monarchs have come to experience and enjoy.

    2016StrategyIndieSimulation14.99 USDDeck VerifiedSteam ↗
  7. EcoGnomix

    WHY THIS

    Ranked #7 for STEM Defense fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with STEM Defense.

    A quirky mix of roguelite and city builder. Build a lively little city above, by looting mystical caves with a team of gnomes below! Use multiple runs to unlock upgrades and abilities to help your gnomes venture deeper into the dangerous underground.

    2024StrategyIndieSimulation19.99 USDDeck VerifiedSteam ↗
  8. Hexguardian

    WHY THIS

    Ranked #8 for STEM Defense fans by collaborative filtering across millions of Steam libraries. Shares Strategy with STEM Defense.

    Hexguardian is a roguelite, tower defense game where you build your own maps with hexagonal tiles! Build and upgrade towers, recruit armies, learn spells, construct wonders and place hexagonal tiles to create a path to enhance your defenses. With plenty of game modes and talents to unlock!

    2024Strategy11.99 USDDeck PlayableSteam ↗

Cheaper alternatives

Games in the same vein priced at least 40% below STEM Defense at current Steam store prices.

  1. Garry's Mod

    WHY THIS

    Priced ~50% under STEM Defense on Steam right now. Shares Indie with STEM Defense.

    Garry's Mod is a physics sandbox. There aren't any predefined aims or goals. We give you the tools and leave you to play.

    2006IndieSimulationCasual4.99 USDDeck PlayableSteam ↗
  2. Vampire Survivors

    WHY THIS

    Priced ~50% under STEM Defense on Steam right now. Shares Indie with STEM Defense.

    Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!

    2022ActionIndieRPG4.99 USDDeck VerifiedSteam ↗
  3. Cookie Clicker

    WHY THIS

    Priced ~50% under STEM Defense on Steam right now. Shares Strategy and Indie with STEM Defense.

    An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam.

    2021StrategyIndieSimulation4.99 USDDeck PlayableSteam ↗
  4. WEBFISHING

    WHY THIS

    Priced ~50% under STEM Defense on Steam right now. Shares Indie with STEM Defense.

    WEBFISHING a multiplayer chatroom-focused fishing game! Relax and fish (on the web!)

    2024IndieMassively MultiplayerCasual4.99 USDSteam ↗
  5. POSTAL 2

    WHY THIS

    Priced ~90% under STEM Defense on Steam right now. Shares Indie with STEM Defense.

    Live a week in the life of "The POSTAL Dude"; a hapless everyman just trying to check off some chores. Buying milk, returning an overdue library book, getting Gary Coleman's autograph, what could possibly go wrong?

    2012ActionIndieAdventure0.99 USDDeck VerifiedSteam ↗
  6. Plants vs. Zombies GOTY Edition

    WHY THIS

    Priced ~50% under STEM Defense on Steam right now. Shares Strategy with STEM Defense.

    Zombies are invading your home, and the only defense is your arsenal of plants! Armed with an alien nursery-worth of zombie-zapping plants like peashooters and cherry bombs, you'll need to think fast and plant faster to stop dozens of types of zombies dead in their tracks.

    2009Strategy4.99 USDDeck PlayableSteam ↗
  7. Buckshot Roulette

    WHY THIS

    Priced ~70% under STEM Defense on Steam right now. Shares Indie with STEM Defense.

    Play Russian roulette with a 12-gauge shotgun. Four enter. One leaves. Roll the dice with your life. Good luck!

    2024ActionIndieSimulation2.99 USDDeck PlayableSteam ↗
  8. Brotato

    WHY THIS

    Priced ~50% under STEM Defense on Steam right now. Shares Indie with STEM Defense.

    Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.

    2023ActionIndieRPG4.99 USDDeck VerifiedSteam ↗

Free alternatives

Free-to-play games that recommended players of this title also tend to enjoy.

  1. Ultimate Custom Night

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with STEM Defense.

    Welcome to the ultimate FNAF mashup, featuring 50 selectable characters and custom difficulties!

    2018ActionIndieFree To PlayFreeSteam ↗
  2. Indigo Park: Chapter 1

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with STEM Defense.

    Explore the abandoned childhood wonder of Indigo Park! Guided by Rambley the Raccoon, help restore power to the destroyed amusement park while you run from the reason it shut down.

    2024ActionIndieAdventureFreeDeck PlayableSteam ↗
  3. The Looker

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with STEM Defense.

    You wake up, alone, on a strangely familiar island full of puzzles that will frustrate and annoy you.

    2022IndieFreeDeck PlayableSteam ↗
  4. Coloring Pixels

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with STEM Defense.

    A relaxing coloring by numbers game. Enjoy completing a variety of images with differing themes, complexity, and sizes.

    2018IndieFree To PlayCasualFreeSteam ↗
  5. Landfall Archives

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Strategy and Indie with STEM Defense.

    Break into the Landfall Archives to steal and play previously unreleased games, demos, interactive slide shows, and even an unreleased version of Totally Accurate Battle Simulator from 2017!

    2023ActionStrategyIndieFreeSteam ↗
  6. Hello Neighbor Alpha 2

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Strategy and Indie with STEM Defense.

    Welcome to Alpha 2 of Hello Neighbor. Play against an advanced, self-learning AI in what eventually became Act 1 of Hello Neighbor - the stealth horror home invasion sim.

    2019StrategyIndieAdventureFreeSteam ↗
  7. Samorost 1

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with STEM Defense.

    Explore the beginnings of the Samorost series in the space gnome’s original bite-sized adventure, formerly released in 2003. Now with remastered sounds, enhanced graphics, and new music by Floex.

    2021IndieAdventureCasualFreeSteam ↗
  8. Epic Battle Fantasy 3

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with STEM Defense.

    Epic Battle Fantasy 3 is a silly turn-based JRPG, full of useless NPCs, rabid cats, childish humor, unreasonably large weapons, anime boobs, and other nonsense. And it's totally free!

    2016IndieAdventureRPGFreeDeck PlayableSteam ↗

Plays great on Steam Deck

Valve-Verified or Playable picks from the similar pool — ready to go on Deck out of the box.

  1. Landnama

    WHY THIS

    Deck Verified — runs on Steam Deck out of the box. Shares Strategy with STEM Defense.

    Face the judgment of winter’s deadly toll as you lead the first Viking clans to settle Iceland in this non-violent, rogue-lite survival base builder.

    2023Strategy13.99 USDDeck VerifiedSteam ↗
  2. Kingdom: New Lands

    WHY THIS

    Deck Verified — runs on Steam Deck out of the box. Shares Strategy and Indie with STEM Defense.

    Kingdom: New Lands builds upon the award-winning gameplay and mystery of Kingdom by introducing an abundance of new content to the IGF-nominated title while maintaining the simplicity and depth that legions of monarchs have come to experience and enjoy.

    2016StrategyIndieSimulation14.99 USDDeck VerifiedSteam ↗
  3. EcoGnomix

    WHY THIS

    Deck Verified — runs on Steam Deck out of the box. Shares Strategy and Indie with STEM Defense.

    A quirky mix of roguelite and city builder. Build a lively little city above, by looting mystical caves with a team of gnomes below! Use multiple runs to unlock upgrades and abilities to help your gnomes venture deeper into the dangerous underground.

    2024StrategyIndieSimulation19.99 USDDeck VerifiedSteam ↗

Frequently asked about STEM Defense

How much does STEM Defense cost?
STEM Defense is listed on Steam at 9.99 USD (current store price; Steam sales may reduce this temporarily).
What games are most similar to STEM Defense?
Based on Steam play patterns and shared genres/tags, the games most often recommended alongside STEM Defense are Terrorformer TD, Deep Among the Swarm, Landnama.
Who developed STEM Defense?
STEM Defense was developed by NoOneGames.

imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on STEM Defense.

For library-aware picks tuned to your specific taste, sign in with Steam on the home page.

27 Games Like STEM Defense — Ranked for 2026 · imho.run