IMHO.

Single-player games like Fatal Dopamine/ 致命多巴胺

Below are 8 single-player Steam games similar to Fatal Dopamine/ 致命多巴胺, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Fatal Dopamine/ 致命多巴胺 page.

Ranked picks

  1. 1
    Card Warrior — Steam game cover

    Card Warrior

    Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.

    Card Warrior is a wuxia roguelike card game combining martial arts and card mechanics. Play cards to strike, parry, counterattack, and strike relentlessly when you spot enemies’ flaws. Walk the path of a worrior. What kind of hero will you be?

    StrategyIndieSingle-playerSimilar games →
  2. 2
    One More Hand — Steam game cover

    One More Hand

    Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.

    A trick-taking roguelite card game set in the Curator's rigged room. Set the lead suit, spin the slots, use the claw machine, and win your ticket out of this digital nightmare.

    StrategyIndieSingle-playerSimilar games →
  3. 3
    Cardtonia — Steam game cover

    Cardtonia

    Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.

    A deckbuilding card game. Summon minions, sacrifice wounded ones to summon stronger minions, use their effects to grow fast, and defeat your opponent within a set number of turns. Keep upgrading your minions, discover Treasures, build unique decks, and aim to reach the top of Diamond Town!

    StrategyIndieRPGSingle-playerSimilar games →
  4. 4
    CARDUNGEON — Steam game cover

    CARDUNGEON

    Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.

    A hand-drawn dungeon Roguelike card game where everything is a card. Explore dangerous dungeons, fight enemies, discover events, recruit companions, collect gear, and build powerful card combinations. Adapt your strategy and defeat the Boss.

    StrategyIndieSingle-playerSimilar games →
  5. 5
    Inga Chronicle — Steam game cover

    Inga Chronicle

    Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.

    A deckbuilding roguelike where real history makes the strongest combos. 200+ cards, 100+ Causal Combos rooted in authentic Japanese history — from Asuka to Bakumatsu. The more you know, the stronger you get.

    2026Strategy11.04 USDSingle-playerSimilar games →
  6. 6
    Starhand — Steam game cover

    Starhand

    Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.

    A roguelite deckbuilder where your cards are your ship. Every card draws on a system — weapons, shields, engines, scanners, engineering. Enemies don't just chew your hull, they knock systems offline and lock those cards out of your hand. Six pilots, 355 cards, eight zones. Improvise or die.

    2026StrategyIndieRPGSingle-playerSimilar games →
  7. 7
    DEATHMATE — Steam game cover

    DEATHMATE

    Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.

    DEATHMATE is a chess-themed roguelike deckbuilder. Build an army of pieces, stack a deck full of moves, and battle your way across the map towards the Grim Reaper.

    StrategyIndieSingle-playerSimilar games →
  8. 8
    Tower's Gambit — Steam game cover

    Tower's Gambit

    Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.

    A card-based roguelike where every flip could be your fortune — or your doom. Descend a pyramid of cards, dodge deadly matches, play face cards at the perfect moment, and risk your score against 10 brutal boss towers. No two runs are the same.

    StrategyIndieCasualSingle-playerSimilar games →