Single-player games like Fatal Dopamine/ 致命多巴胺
Below are 8 single-player Steam games similar to Fatal Dopamine/ 致命多巴胺, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Fatal Dopamine/ 致命多巴胺 page.
Ranked picks
- 1
Cardtonia
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A deckbuilding card game. Summon minions, sacrifice wounded ones to summon stronger minions, use their effects to grow fast, and defeat your opponent within a set number of turns. Keep upgrading your minions, discover Treasures, build unique decks, and aim to reach the top of Diamond Town!
- 2
Inga Chronicle
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A deckbuilding roguelike where real history makes the strongest combos. 200+ cards, 100+ Causal Combos rooted in authentic Japanese history — from Asuka to Bakumatsu. The more you know, the stronger you get.
- 3
Tower's Gambit
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A card-based roguelike where every flip could be your fortune — or your doom. Descend a pyramid of cards, dodge deadly matches, play face cards at the perfect moment, and risk your score against 10 brutal boss towers. No two runs are the same.
- 4
Vortex
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
You just wanted to play a relaxing game of Sudoku, right? Too bad your PC just got infected. VORTEX is a chaotic deck-building roguelike where malware rewrites the rules of the classic puzzle. Build your deck, adapt to the mutating viruses, and survive the digital chaos!
- 5
Divine Sin: Death Duel
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A dark fantasy deckbuilding roguelike featuring a unique Clash combat system, where every duel becomes an exchange of calculated moves and deadly counters.
- 6
Piroker
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
Poker turned into pirate mayhem. Build powerful relics, discover unique builds, and adapt your tactics to dominate the Seven Seas.
- 7
Up Cards
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
UP CARDS is a light roguelike card game. In this exciting journey, you need to control the card situation, play the best combinations, stack additional effects to turn the tide, choose your permanent rewards, and reach new heights through different strategic builds.
- 8
Castle V Castle
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A stylish single player 1v1 card game funded and supported by Slay the Spire's Casey Yano and inspired by browser classic Castle Wars. Build up your castle and knock down your opponent's brick by brick!