Single-player games like Fatal Dopamine/ 致命多巴胺
Below are 8 single-player Steam games similar to Fatal Dopamine/ 致命多巴胺, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Fatal Dopamine/ 致命多巴胺 page.
Ranked picks
- 1

Card Warrior
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
Card Warrior is a wuxia roguelike card game combining martial arts and card mechanics. Play cards to strike, parry, counterattack, and strike relentlessly when you spot enemies’ flaws. Walk the path of a worrior. What kind of hero will you be?
- 2

One More Hand
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A trick-taking roguelite card game set in the Curator's rigged room. Set the lead suit, spin the slots, use the claw machine, and win your ticket out of this digital nightmare.
- 3

Cardtonia
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A deckbuilding card game. Summon minions, sacrifice wounded ones to summon stronger minions, use their effects to grow fast, and defeat your opponent within a set number of turns. Keep upgrading your minions, discover Treasures, build unique decks, and aim to reach the top of Diamond Town!
- 4

CARDUNGEON
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A hand-drawn dungeon Roguelike card game where everything is a card. Explore dangerous dungeons, fight enemies, discover events, recruit companions, collect gear, and build powerful card combinations. Adapt your strategy and defeat the Boss.
- 5

Inga Chronicle
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A deckbuilding roguelike where real history makes the strongest combos. 200+ cards, 100+ Causal Combos rooted in authentic Japanese history — from Asuka to Bakumatsu. The more you know, the stronger you get.
- 6

Starhand
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A roguelite deckbuilder where your cards are your ship. Every card draws on a system — weapons, shields, engines, scanners, engineering. Enemies don't just chew your hull, they knock systems offline and lock those cards out of your hand. Six pilots, 355 cards, eight zones. Improvise or die.
- 7

DEATHMATE
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
DEATHMATE is a chess-themed roguelike deckbuilder. Build an army of pieces, stack a deck full of moves, and battle your way across the map towards the Grim Reaper.
- 8

Tower's Gambit
Single-player alternative to Fatal Dopamine/ 致命多巴胺 — playable solo, no multiplayer required. Shares Strategy with Fatal Dopamine/ 致命多巴胺.
A card-based roguelike where every flip could be your fortune — or your doom. Descend a pyramid of cards, dodge deadly matches, play face cards at the perfect moment, and risk your score against 10 brutal boss towers. No two runs are the same.