Single-player games like Isomer
Below are 10 single-player Steam games similar to Isomer, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Isomer page.
Ranked picks
- 1

Mutant Fish Lab
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Action and Strategy with Isomer.
Collect, extract, and replicate bizarre genetic combinations to create the strongest—or strangest—creatures imaginable.
- 2

A Lanterns Glow
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Action and Strategy with Isomer.
ALG is a challenging top-down survival RPG. Explore an expansive, randomly generated world shrouded in darkness. Gather resources, craft items, construct buildings, fight strange creatures, and study magic and science to survive and solve the many mysteries of the forest.
- 3

EDEN STAR
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Action and Strategy with Isomer.
Eden Star is a fast paced Sci-Fi survival game that blends unique physics based combat, destructible environments and free-form construction with the exploration of a hostile alien world.
- 4

Astro Colony
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Action and Strategy with Isomer.
Explore endless Universe and create the most efficient constellation of colonies. Build conveyor systems to automate production. Take care of Astronauts and their needs! Establish new colonies as part of intergalactic simulation.
- 5

Celestial Command
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Action and Strategy with Isomer.
Mine asteroids, salvage space debris, design your own small or massive spacecraft using individual functional components, complete missions, and engage in battles against enemies in a vast galaxy with realistic physics based on orbital mechanics or in a classic physics mode.
- 6

Gunsmith
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Action and Strategy with Isomer.
Build up your own arms manufacturing company. Find your factory, buy resources, produce a wide range of military equipment to sell to the highest bidder. Good or bad? That's up to you, who you do business with is your choice. Don't ask, don't tell, get paid. After all, war is about making money.
- 7

Gnomoria
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Strategy and Indie with Isomer.
Gnomoria is a sandbox village management game where you help lead a small group of gnomes, who have set out on their own, to thrive into a bustling kingdom! Anything you see can be broken down and rebuilt elsewhere.
- 8

XCOM® 2
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Strategy with Isomer.
XCOM 2 is the sequel to XCOM: Enemy Unknown, the 2012 award-winning strategy game of the year. Earth has changed and is now under alien rule. Facing impossible odds you must rebuild XCOM, and ignite a global resistance to reclaim our world and save humanity.
- 9

Dwarf Fortress
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Strategy and Indie with Isomer.
Build a fortress and try to help your dwarves survive against a deeply generated world. Keep your dwarves happy, grow their community and beware of digging too deeply. The deepest, most intricate simulation of a world that's ever been created.
- 10

Minecraft Legends
Single-player alternative to Isomer — playable solo, no multiplayer required. Shares Action and Strategy with Isomer.
Discover the mysteries of Minecraft Legends, a new action strategy game. Explore a gentle land of rich resources and lush biomes on the brink of destruction. The ravaging piglins have arrived, and it’s up to you to inspire your allies and lead them in strategic battles to save the Overworld!