Single-player games like SynthetiCell BioClicker
Below are 9 single-player Steam games similar to SynthetiCell BioClicker, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like SynthetiCell BioClicker page.
Ranked picks
- 1
Mining Factory
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Strategy and Indie with SynthetiCell BioClicker.
Can mine, can fight, and has sisters, collecting more than 30 types of ore such as iron ore, copper ore, manganese ore, chrome ore, vanadium ore, titanium ore, etc. Team up to break through the 100th floor
- 2
Mining Copper
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Strategy and Indie with SynthetiCell BioClicker.
Collect copper ore and pass through various smelting equipment to produce copper plates.
- 3
Gold Rush Clicker
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Strategy and Indie with SynthetiCell BioClicker.
Dive into "Gold Rush Clicker," an idle clicker game where you start as a novice miner. Tap to mine gold, buy upgrades, and face strategic challenges. With procedurally generated levels, stunning graphics, and Steam achievements, it's an endless journey to become the ultimate mining tycoon!
- 4
Patient Zero: Plague Idle
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Strategy and Indie with SynthetiCell BioClicker.
Patient Zero: Plague Idle is an idle / incremental outbreak builder where you create the perfect pathogen through mutation trees, global infection, long-term upgrades, and new pathogen unlocks. Turn the world into your lab.
- 5
Fracture Field
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Indie and Simulation with SynthetiCell BioClicker.
Fracture Field is an idle/incremental quarry mining game. Shatter rocks with timed swings then invest your earnings into upgrades. Build a fleet of drones to automate your empire, bomb tough layers, and unlock powerful prestige upgrades on your journey to master the quarry.
- 6
Moose Miners
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Strategy and Indie with SynthetiCell BioClicker.
Take control of a mining operation run by moose. They mine and sell the gems. You need to decide where to spend the profits. Hire more miners and upgrade their gear. Buy new rails and minecarts to get deeper into the mine. The deeper you get the more valuable gems you will find.
- 7
Incremental Town RPG
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Strategy and Indie with SynthetiCell BioClicker.
Incremental Town RPG lets you build and manage a thriving village. Master resource management, develop a robust economy, and enjoy a relaxing experience as you equip your settlement to conquer new lands and challenges!
- 8
SimPocalypse
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Strategy and Indie with SynthetiCell BioClicker.
A civilization simulator where you manage billions of people and rebuild millions of structures. Improve your economy, research, advance, battle, and much more! Play at your own pace by controlling game speed and automate various tasks!
- 9
Xtreme Club Racing
Single-player alternative to SynthetiCell BioClicker — playable solo, no multiplayer required. Shares Indie with SynthetiCell BioClicker.
Get behind the wheel in one of the most frenetic extreme driving games. Various interactive elements such as hurricanes, lava balls, giant spinning tops, which will cross in the middle of the competition track and will put your reflexes and extreme driving to the limit.