Single-player games like Propa.
Below are 9 single-player Steam games similar to Propa., ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Propa. page.
Ranked picks
- 1
Nano Fighter Anti Disease
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Simulation with Propa..
Nano Fighter Anti Disease is a flight action game. Controlling a nanoscale fighter, flies over the acid sea of digestive system, passes through the scarred inflammatory lesions, launch a fierce attack towards various pathogens with medicine ammos and biological missiles.
- 2
Before I Turn: Survival Auto Battler
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Strategy and Simulation with Propa..
You've been bitten. Hours before you turn. All you have left: a clock running out and a deserted hospital lab. Identify the virus, synthesize your antiviral, and test it. But every win teaches it to resist you. Before I Turn blends survival, auto battler and simulation into one experience.
- 3
Pestis
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Simulation with Propa..
A young Plague Doctor, only to learn that the Academy sent to a small village, which, like the whole country is gripped by plague
- 4
Bio Inc. Redemption
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Strategy and Simulation with Propa..
Bio Inc.: Redemption is a realistic simulation and strategy game in which you make life or death decisions. Create a deadly illness to infect and torment your victim or play as the head of a medical team and hopefully find a cure to save your human patient. Will you be the plague or preserve humanity?
- 5
Galacticare
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Strategy and Simulation with Propa..
Build, manage and optimise intergalactic hospitals! Recruit staff to satisfy the whims of various alien species, and cure their bizarre illnesses - for money! Save the (literal) Galaxy in story mode, or head into sandbox to design the hospital of your dreams.
- 6
ICBM
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Strategy with Propa..
ICBM is a real-time strategy game of nuclear destruction. Research new technologies, build up your nuclear stockpile and use a combination of ships, planes and missiles to strike at the heart of your opponents’ cities while keeping your population safe from harm.
- 7
Sand:box
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Simulation with Propa..
"Falling sand" style particle sandbox, now with circuits and stickmen!
- 8
First Strike
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Strategy and Simulation with Propa..
FIRST STRIKE is a fast paced real time strategy game where you play one of the twelve biggest nuclear superpowers of the world – from known superpowers like the USA to an upstart hellraiser like North Korea – and try to be the last one remaining when the whole world blows to smithereens.
- 9
GlobalQuarantine
Single-player alternative to Propa. — playable solo, no multiplayer required. Shares Strategy and Simulation with Propa..
Running an international organization called the Global Quarantine Bureau, dealing with pandemics and public health issues worldwide, while also ensuring increasing revenue and personal enrichment.