Games like Supre-Immune
Join a roguelike action where cute immune cells battle viruses. Collect data in fast-paced combat, gain weapons and abilities through evolution, or level up to grow stronger. The fun of building your own super immune cell with different combinations each run is up to you!

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Ranked by collaborative filtering across millions of Steam libraries plus content overlap on genres, tags, and developers.
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Loki's Revenge
Loki’s Revenge is a survivors-like roguelite where you play as Norse gods fighting Loki’s army of monsters! Level up to gain powerful upgrades and explore hand-crafted maps to find secrets. Build the ultimate overpowered god with permanent upgrades and master each god’s signature ability.
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Genome Guardian 2
COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!
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Supercat Survivors
Meow! This is a cat-themed Survivor-like game where you control an adorable Supercat! Battle monsters to level up, collect items, upgrade weapons, and experiment with strategic builds to fight off invading creatures threatening Meow Star.
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Gunlocked 2
Movement is your weapon. A sci-fi action roguelike and shmup combined, in Gunlocked 2 you'll pilot and upgrade a state-of-the-art warship against endless waves of deadly aliens. Deep customization, branching paths, and tons of unlockables offer endless replayability!
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Noobs Are Coming
YOU ARE THE FINAL BOSS. Brutal synergy arena roguelike. Pick your Final Boss character, equip boss patterns and combine tons of attacks to create unique builds. Play solo or in co-op!
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Rhythm Storm
Rhythm Storm is a roguelike bullet heaven with stunning vector graphics, rhythmic action, and overwhelming swarms of enemies. Your vehicle aims and fires freely while everything else dances and moves to the beat in this spectacular audio-visual experience.
Plays great on Steam Deck
Valve-Verified or Playable picks from the similar pool — ready to go on Deck out of the box.
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Gunlocked 2
Movement is your weapon. A sci-fi action roguelike and shmup combined, in Gunlocked 2 you'll pilot and upgrade a state-of-the-art warship against endless waves of deadly aliens. Deep customization, branching paths, and tons of unlockables offer endless replayability!
- 3

Noobs Are Coming
YOU ARE THE FINAL BOSS. Brutal synergy arena roguelike. Pick your Final Boss character, equip boss patterns and combine tons of attacks to create unique builds. Play solo or in co-op!
- 4

Rhythm Storm
Rhythm Storm is a roguelike bullet heaven with stunning vector graphics, rhythmic action, and overwhelming swarms of enemies. Your vehicle aims and fires freely while everything else dances and moves to the beat in this spectacular audio-visual experience.
Frequently asked about Supre-Immune
- How much does Supre-Immune cost?
- Supre-Immune is listed on Steam at 6.99 USD (current store price; Steam sales may reduce this temporarily).
- What games are most similar to Supre-Immune?
- Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Supre-Immune are Compadrone: Land Wars, Loki's Revenge, Genome Guardian 2.
- Who developed Supre-Immune?
- Supre-Immune was developed by Indion and published by Indion, Imperfect Games.
imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on Supre-Immune.
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