Single-player games like Plague Doctor And Panacea
Below are 14 single-player Steam games similar to Plague Doctor And Panacea, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Plague Doctor And Panacea page.
Ranked picks
- 1
A Night in Prison
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Indie with Plague Doctor And Panacea.
You come to your senses in a cell that looks like you are in some kind of prison. It's almost silent, but sometimes there are some sounds.
- 2
Laboratory of Nightmares
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Indie with Plague Doctor And Panacea.
You are one of the best fighters of the GIBAR unit, and therefore you were sent to destroy a secret laboratory guarded by armed soldiers. This is a dynamic game with a top view in which you have to survive in a secret laboratory and find a way out of it.
- 3
Heart Of Squid
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Indie with Plague Doctor And Panacea.
Returning from vacation, he finds that the island has been invaded by workers who plan to cut down all the trees and blow up the island. Not agreeing with this decision, Grandpa decides to engage in an unequal battle to defend his home.
- 4
Madness on Display
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Indie with Plague Doctor And Panacea.
Venture into the world of chilling psychological horror, where the line between reality and nightmare is thinner than a spider's web. Grandview is not just a game, it is a test for your nerves and mind.
- 5
The Wild
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Indie with Plague Doctor And Panacea.
Step into the wild, the untamed world of Earth, where you'll take control of a wide variety of animals. Survive the harsh environment, hunt, forage, breed and fight through an ever changing ecosystem.
- 6
Kepler 186F
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Indie with Plague Doctor And Panacea.
Kepler 186F is a narrative-driven sci-fi thriller that puts adventure-puzzle gameplay front and centre. As the Type-37 Crisis Response Robot, you embark on a pure adventure-puzzle odyssey across the frozen dark side of Kepler 186F to investigate the vanished colony.
- 7
The Home Way
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Indie with Plague Doctor And Panacea.
A long journey across the waves and obstacles, testing your patience and skill. Can you reach home?
- 8
Pigeon Flight Simulator
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Indie with Plague Doctor And Panacea.
Pigeon Flight Simulator offers a peaceful flying experience over the city with relaxing music. Escape stress, feel the freedom of the sky, and enjoy the tranquility!
- 9
Degrees
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required.
Degrees - racing game with two modes: single and multiplayer mode for 4 players. With a view from above, you control the victim machine on the map, which is pursued by hunters. Escape them and hide in the bushes, so it will be harder for them to find you.
- 10
Underwater hunting
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Indie and Adventure with Plague Doctor And Panacea.
Underwater hunting: Plunge into the underwater world. Your character-a small fish piranha. The glory of these river predators is truly black - river killers, bloodthirsty robbers, river hyenas, sharks. And she always wants to eat.
- 11
Oil Baron
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Indie and Simulation with Plague Doctor And Panacea.
The game has 7 locations with special tasks. You must fulfill them until the end of the day. It can be used to collect N amount of oil or earn several thousand $. To start playing, you need to choose the complexity of the game. There are 5 difficulty levels (easy-normal-difficult-very complicated-insane).
- 12
Oops!!! Puzzles!!!
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Indie and Adventure with Plague Doctor And Panacea.
We offer you a puzzle game. The meaning of the game – making a mosaic pattern that you want to add up from a variety of fragments of different shapes. The greatest interest in this game will cause thrill-seekers, as it contains scary pictures (horror).
- 13
Base Dune
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action and Adventure with Plague Doctor And Panacea.
Base Dune 3D is a first-person shooter in which you have to go through a large secret laboratory destroying enemies. You can simply move around the game world and shoot the weapons that are given in the game.
- 14
MOLOGA
Single-player alternative to Plague Doctor And Panacea — playable solo, no multiplayer required. Shares Action with Plague Doctor And Panacea.
Description: in 1935, the leadership of the USSR decided to build a new reservoir in one of the regions of the republic. Almost all people left villages and towns, but some refused to leave their homes.