Single-player games like Only One Brain Left
Below are 8 single-player Steam games similar to Only One Brain Left, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Only One Brain Left page.
Ranked picks
- 1

Lost Zone: Survival
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
Lost Zone: Survival ,Survive in a vast open world by battling harsh conditions, hunger, and unknown threats. Explore with friends, gather resources, fish, farm, and craft tools to stay alive. Beware of other players who can steal your hard-earned loot. Only the strongest will survive!
- 2

Ardem
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
The zombies ended the world. You're going to switch it back on. Ardem is an open-world zombie survival game in an immersive handcrafted world. Restore electricity, rebuild vehicles, construct your base, and permanently reshape the world. Solo, co-op, or on up-to-64-player PvE, PvP, and RP servers.
- 3

Mortal Frame: Reforged in Survival
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
"Mortal Frame" is a sci-fi RPG combining open-world exploration and sandbox survival. The player explores a challenging world, gathers resources, crafts gear, captures AI companions, and upgrades modification chips to enhance their abilities, facing powerful foes and uncovering hidden mysteries.
- 4

Frozen Ship
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Strategy with Only One Brain Left.
Frozen Ship is an open-world survival game where you manage an entire city on wheels. Building, crafting, research, medicine, resource gathering, and hunting — you decide what your people will do and how your city will develop.
- 5

THE DEAD WE KNEW: Open World Survival
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Adventure with Only One Brain Left.
Explore a dangerous open world, loot abandoned places, build your shelter, produce food, and manage your resources. Survive alone or in co-op against zombies, hostile humans, and the growing dangers that come with the fog.
- 6

The Road Behind Us
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required.
The Road Behind Us is an urban survival game about about you, your dog, and a dead city. Explore abandoned skyscrapers, rooftops, basements, underpasses, and more. Craft out of a semi truck and take your base with you, or fix up an abandoned building and call it home.
- 7

Frostrail
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
Through the frost, death follows the tracks. Dive into a ruthless survival FPS, solo or co-op. Explore, scavenge, craft and fight to endure a frozen, corrupted world. Operate and upgrade your steam-powered train through an unforgiving wasteland, where every choice is a matter of survival.
- 8

DREADZONE
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
Dreadzone is a survival game set in a deadly quarantine zone. Scavenge for resources, craft tools, build shelter, and survive against dangerous animals, zombies, mutants, and other survivors. Explore the zone where desperation drives everyone to do whatever it takes to survive.