Single-player games like Only One Brain Left
Below are 8 single-player Steam games similar to Only One Brain Left, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Only One Brain Left page.
Ranked picks
- 1
Mortal Frame: Reforged in Survival
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
"Mortal Frame" is a sci-fi RPG combining open-world exploration and sandbox survival. The player explores a challenging world, gathers resources, crafts gear, captures AI companions, and upgrades modification chips to enhance their abilities, facing powerful foes and uncovering hidden mysteries.
- 2
Frozen Ship
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Strategy with Only One Brain Left.
Frozen Ship is a narrative adventure set in the harsh conditions of a post-apocalyptic world, combining open-world survival with managing an entire mobile city.
- 3
The Road Behind Us
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required.
The Road Behind Us is an urban survival game about about you, your dog, and a dead city. Explore abandoned skyscrapers, rooftops, basements, underpasses, and more. Craft out of a semi truck and take your base with you, or fix up an abandoned building and call it home.
- 4
Mr. Nomad
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
Mr. Nomad is a survival base-building, tower defense game set in a post-apocalyptic world. Set a fortified base around your camper, craft, endure brutal zombie raids, hide what is precious to you in underground bunker and embark on dangerous missions in search of resources.
- 5
Frostrail
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
Through the frost, death follows the tracks. Dive into a ruthless survival FPS, solo or co-op. Explore, scavenge, craft and fight to endure a frozen, corrupted world. Operate and upgrade your steam-powered train through an unforgiving wasteland, where every choice is a matter of survival.
- 6
DREADZONE
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
Dreadzone is a survival game set in a deadly quarantine zone. Scavenge for resources, craft tools, build shelter, and survive against dangerous animals, zombies, mutants, and other survivors. Explore the zone where desperation drives everyone to do whatever it takes to survive.
- 7
Outbreak Island
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
Survive on a remote Island, where a mysterious Outbreak awakens bloodthirsty monsters at night. Craft, build and defend your base in the brutal world of Outbreak Island, an open-world sandbox survival horror game.
- 8
MISERY
Single-player alternative to Only One Brain Left — playable solo, no multiplayer required. Shares Action and Indie with Only One Brain Left.
MISERY is a 1–5 player co-op survival game set in a nuclear disaster zone. Here, every day is a struggle: search radioactive ruins for resources, build your bunker, craft weapons, and explore a weird, procedurally-generated world with your friends. Beware of anomalies, monsters, and armed bandits.