Single-player games like Star Trek: Infection
Below are 14 single-player Steam games similar to Star Trek: Infection, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Star Trek: Infection page.
Ranked picks
- 1

Tranquil Cove
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Indie with Star Trek: Infection.
Your mother recently passed away, and her mysterious childhood home in a small town called Tranquil Cove was passed down to you. In an attempt to learn about your mothers mysterious past, you go to investigate. Nothing could prepare you for what you find there...
- 2

Take Care VR
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Indie with Star Trek: Infection.
"Take Care VR" thrusts players into adrenaline-fueled battles against hordes of menacing zombies. Armed with an arsenal of weapons, survive intense encounters, solve puzzles, and navigate challenging levels. With a pulse-pounding atmosphere, prepare for an exhilarating virtual reality experience.
- 3

Syndrome
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Adventure with Star Trek: Infection.
Syndrome, a sci-fi survival horror game that places you in a living hell inside a doomed starship. Find out what happened to your lost crew. Run. Hide. Fight. Survive.
- 4

Afterlife VR
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Adventure with Star Trek: Infection.
Afterlife VR is a deeply immersive horror game. As Adam Bernhard, a young rookie police officer on a night patrol, you receive a call that will change your life forever. Uncover secrets hidden deep within the Black Rose mental hospital walls, where most of the patients pose a great danger.
- 5

Dreadhalls
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Indie and Adventure with Star Trek: Infection.
You are trapped deep inside a massive dungeon. Explore it, survive it and find a way to escape. Your only weapons will be stealth, your own courage, and a faint light. Dreadhalls is an intense and scary experience, not for the faint of heart. You have been warned!
- 6

Cosmodread
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Indie with Star Trek: Infection.
Cosmodread is a VR survival horror roguelike about escaping a dying spaceship filled with nightmares. Stranded in a hostile universe, you must explore, survive, and find your way back to the safety of Earth.
- 7

MADiSON VR
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Indie with Star Trek: Infection.
MADiSON VR now plunges you even deeper into its immersive and terrifying world. With the utilization of an instant camera in your virtual hands, bridge the gap between our world and the unknown. Snap photos, develop them by yourself to solve puzzles, explore the shadows and above all, survive.
- 8

Dead Space
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Adventure with Star Trek: Infection.
The sci-fi survival-horror classic returns, completely rebuilt to offer an even more immersive experience — including visual, audio, and gameplay improvements — while staying faithful to the original game’s thrilling vision.
- 9

System Shock® 2 (1999)
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action with Star Trek: Infection.
"Remember, it is my will that guided you here. It is my will that gave you your cybernetic implants, the only beauty in that meat you call a body. If you value that meat... you will do as I tell you." The cult classic sci-fi horror FPS-RPG has returned.
- 10

Half-Life: Alyx
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Adventure with Star Trek: Infection.
Half-Life: Alyx is Valve’s VR return to the Half-Life series. It’s the story of an impossible fight against a vicious alien race known as the Combine, set between the events of Half-Life and Half-Life 2. Playing as Alyx Vance, you are humanity’s only chance for survival.
- 11

System Shock 2: 25th Anniversary Remaster
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Adventure with Star Trek: Infection.
System Shock® 2: 25th Anniversary Remaster is a genre defining experience that established innovative game-play mechanics that are a staple of the FPS and RPG genre today. Survive the wretched corridors of the Von Braun. Your training has prepared you for this.
- 12

Kayak VR: Mirage
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Indie and Adventure with Star Trek: Infection.
Kayak VR: Mirage is a jaw-dropping and exhilarating journey through beautiful locations, made for Virtual Reality. Maneuver our fully physically accurate kayak around checkpoints and crown yourself the fastest, or take it easy and use the free roam mode and enjoy the scenery.
- 13

Stargaze
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Indie and Adventure with Star Trek: Infection.
Gaze into the stars as a curious astronomer in this VR adventure of magic & science. Manipulate a strangely powerful telescope and influence a galaxy of planets and their inhabitants for the better. Take photos and conduct intricate research to uncover the deepest cosmic secrets.
- 14

Mixture
Single-player alternative to Star Trek: Infection — playable solo, no multiplayer required. Shares Action and Indie with Star Trek: Infection.
Play as 2 characters at the same time - Alchemist & Knight. Traverse dangerous barren worlds of living metals, ores and crystals to find means of redemption.