Single-player games like Plague Doctor: Medieval Apothecary
Below are 8 single-player Steam games similar to Plague Doctor: Medieval Apothecary, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Plague Doctor: Medieval Apothecary page.
Ranked picks
- 1
Save Us, Doctor Faust!
Single-player alternative to Plague Doctor: Medieval Apothecary — playable solo, no multiplayer required. Shares Indie and Simulation with Plague Doctor: Medieval Apothecary.
Save Us, Doctor Faust! is an immersive medieval doctor simulator where you diagnose diseases, study medicine, and craft remedies from raw ingredients. Examine your patients, grind and distill ingredients, experiment with recipes — and remember: one mistake could cost a life.
- 2
Aboard Titanic
Single-player alternative to Plague Doctor: Medieval Apothecary — playable solo, no multiplayer required. Shares Indie and Simulation with Plague Doctor: Medieval Apothecary.
The Titanic is yours to master. Explore 100% of the ship, race through challenges, navigate by instinct, interact with history. The ultimate spatial puzzle awaits.
- 3
Rescue Operations Simulator
Single-player alternative to Plague Doctor: Medieval Apothecary — playable solo, no multiplayer required. Shares Indie and Simulation with Plague Doctor: Medieval Apothecary.
Rescue Operations Simulator is a game where you play the role of USAR (Urban Search and Rescue) member and a team leader. You will arrange and execute rescue operations from real life catastrophic events that shocked and changed the whole world.
- 4
Herbalist Roman
Single-player alternative to Plague Doctor: Medieval Apothecary — playable solo, no multiplayer required. Shares Simulation with Plague Doctor: Medieval Apothecary.
Step into the role of a medieval herbalist. Study your herbal book, craft macerations, and help your clients by easing their ailments. Christianity is reaching the Slavic village of Drebor, and your choices will determine whether these changes unfold in peace.
- 5
Deep Shift
Single-player alternative to Plague Doctor: Medieval Apothecary — playable solo, no multiplayer required. Shares Indie and Simulation with Plague Doctor: Medieval Apothecary.
Restore a damaged underwater station through hands-on maintenance. Repair pipes, electrical systems and machinery, replace physical components, clean abandoned sectors, and gradually bring the facility back to life in an atmospheric first-person simulation.
- 6
Venice Master
Single-player alternative to Plague Doctor: Medieval Apothecary — playable solo, no multiplayer required. Shares Simulation with Plague Doctor: Medieval Apothecary.
Become a craftsman in the Renaissance Venice. Develop business after business, be resourceful and creative. Many tasks can be completed only if you construct the most suitable machines first. No need to give it any more thought, just roll up your sleeves and get to work!
- 7
Pestis
Single-player alternative to Plague Doctor: Medieval Apothecary — playable solo, no multiplayer required. Shares Indie and Simulation with Plague Doctor: Medieval Apothecary.
A young Plague Doctor, only to learn that the Academy sent to a small village, which, like the whole country is gripped by plague
- 8
CURE - A Hospital Simulator
Single-player alternative to Plague Doctor: Medieval Apothecary — playable solo, no multiplayer required. Shares Simulation with Plague Doctor: Medieval Apothecary.
Manage the night shift of an ER during the apocalypse, solo or with friends online: Diagnose patients. Design and grow your hospital, and defend against the undead while treating the living. If you're a creator, connect the game to Twitch and make the audience your patients for even more fun!