Single-player games like Entropy Department
Below are 9 single-player Steam games similar to Entropy Department, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Entropy Department page.
Ranked picks
- 1

Malignus
Single-player alternative to Entropy Department — playable solo, no multiplayer required. Shares Strategy and Simulation with Entropy Department.
Malignus is a 2D dungeon colony sim and emergent story generator. Play as a boss monster and their underling minions and creatures, expanding your underground dominion, building traps, and defending your prisoners and treasures from invading adventurers.
- 2

Antopolis: The Ant Colony Simulator
Single-player alternative to Entropy Department — playable solo, no multiplayer required. Shares Strategy and Simulation with Entropy Department.
Found a colony, dig a nest, and raise an empire of ants in a giant's back garden. A top-down colony sim of pheromone trails, brood and castes, foraging, and three-way war. Survive a whole backyard food chain of spiders, birds, frogs, and rival ant colonies.
- 3

Territory: Animals Genetic Strategy
Single-player alternative to Entropy Department — playable solo, no multiplayer required. Shares Strategy and Simulation with Entropy Department.
Strategy game about genes and animal species. Evolve, reproduce, expand to new territories, survive, and fight to achieve various goals like biodiversity or dominance in the ecosystem.
- 4

Mars Horizon 2: The Search for Life
Single-player alternative to Entropy Department — playable solo, no multiplayer required. Shares Strategy and Simulation with Entropy Department.
Lead your space agency in The Search for Life in this authentic strategy simulation game. Investigate the solar system and collect evidence of life. Manage base building, rocket designing, launches, and mission planning to Mars and beyond, leading the way in the future of space exploration.
- 5

King of the Dwarves: Underground City Builder
Single-player alternative to Entropy Department — playable solo, no multiplayer required. Shares Strategy and Simulation with Entropy Department.
Build an epic kingdom inside a mountain in this underground city builder. Mine and build in a vast procedurally generated 3D world. Gather resources, research technology, train warriors and engineers, forge weapons, fight monsters and manage hundreds of units. Become the King of the Dwarves!
- 6

After Inc: Revival
Single-player alternative to Entropy Department — playable solo, no multiplayer required. Shares Strategy and Simulation with Entropy Department.
Can you rebuild civilisation after a zombie apocalypse? From the creator of Plague Inc. comes a unique blend of strategic simulation, survival city builder and ‘mini 4X’. Build settlements, harvest resources and shape society as you lead Humanity out of the darkness.
- 7

Ascent of Ashes
Single-player alternative to Entropy Department — playable solo, no multiplayer required. Shares Strategy and Simulation with Entropy Department.
A colony sim set in a post-apocalyptic dystopia. Build and defend your base. Manage your survivors. Engage raiders, aliens, Remnant soldiers and other factions in real-time-with-pause combat. Or use stealth to outwit them. Explore the massive world. Survive at all costs
- 8

Infection Free Zone
Single-player alternative to Entropy Department — playable solo, no multiplayer required. Shares Strategy and Simulation with Entropy Department.
Choose any real region from the world. Choose your base of operations, then rebuild and readapt the buildings around you to create a self-sustaining settlement. Take charge of a group of survivors from your city. And when the night falls - Defend the zone from the infected!
- 9

Mighty Fling
Single-player alternative to Entropy Department — playable solo, no multiplayer required.
Take control of a mighty ball and fling with great precision towards the top of the Tower. Jump through aesthetically pleasing environments filled with intriguing creatures and encounters. Falling is part of the journey, so just keep going. Can you reach the end?