Single-player games like CHEMISTS: Dead Zone
Below are 8 single-player Steam games similar to CHEMISTS: Dead Zone, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like CHEMISTS: Dead Zone page.
Ranked picks
- 1

CHEMISTS: Area of infection
Single-player alternative to CHEMISTS: Dead Zone — playable solo, no multiplayer required. Shares Action and Indie with CHEMISTS: Dead Zone.
A year after the global catastrophe, you woke up in a hospital and don't remember anything. You have to not only find out what happened, but also try to survive in this harsh dangerous world.
- 2

末日货轮:Doomsday Cargo Ship
Single-player alternative to CHEMISTS: Dead Zone — playable solo, no multiplayer required. Shares Adventure and RPG with CHEMISTS: Dead Zone.
Something unexpected happened. Stacked containers, faintly visible docks in the mist, I must disembark. Perhaps there are tools and medicine inside the container. We will face challenges such as disasters, zombies, pirates, and survival pressures until the small boat is built and we return to land.
- 3

From Scratch
Single-player alternative to CHEMISTS: Dead Zone — playable solo, no multiplayer required. Shares Action and Indie with CHEMISTS: Dead Zone.
From Scratch is survival game set in a huge open world of over 50 square kilometers. Fight, craft and acquire resources to survive in a world overrun by zombies and wild animals.
- 4

Infect: The Last Stand
Single-player alternative to CHEMISTS: Dead Zone — playable solo, no multiplayer required. Shares Action and Indie with CHEMISTS: Dead Zone.
Experience brutal Hardcore PvPvE survival powered by Unreal Engine 5. Every decision matters, every step could be your last, and every sound you hear might be your final one. Do you have what it takes to survive the hunt?
- 5

Zovid27: The Last Vaccine
Single-player alternative to CHEMISTS: Dead Zone — playable solo, no multiplayer required. Shares Action and Indie with CHEMISTS: Dead Zone.
Zovid27: The Last Vaccine is an open-world survival game where you fight through a post-apocalyptic world. Scavenge for supplies, hunt, and manage hunger and thirst as you struggle to find a way to reach your family in Europe. Survive, adapt, and overcome deadly factions and infected.
- 6

LIFE EFFECT Survival
Single-player alternative to CHEMISTS: Dead Zone — playable solo, no multiplayer required. Shares Action and Indie with CHEMISTS: Dead Zone.
Survive in a harsh and dangerous world after an alien invasion. Gather resources, craft equipment, fight mutants and massive monsters, use weapons, vehicles and robots, explore territories, defend strongholds and fight for survival.
- 7

The Mutiny
Single-player alternative to CHEMISTS: Dead Zone — playable solo, no multiplayer required. Shares Action and Indie with CHEMISTS: Dead Zone.
A third-person zombie survival RPG built by one solo developer. Scavenge a post-apocalyptic tunnel system, manage gear that breaks, hunger that bites, and a world that gets darker the longer you stay alive.
- 8

WastePunk
Single-player alternative to CHEMISTS: Dead Zone — playable solo, no multiplayer required. Shares Action and Indie with CHEMISTS: Dead Zone.
Third person post apocalyptic RPG-lite. Find beer in a post apocalypse wasteland. Inspired by Fallout 1, Trailer Park Boys and Western genre. Contains foul language.