Single-player games like Patient 0
Below are 8 single-player Steam games similar to Patient 0, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Patient 0 page.
Ranked picks
- 1

Z-Sector
Single-player alternative to Patient 0 — playable solo, no multiplayer required. Shares Action and Indie with Patient 0.
Z-Sector est un jeu de tir intense contre des vagues de zombies. Repoussez des hordes incessantes, obtenez des améliorations tactiques et dominez les classements mondiaux. Combien de vagues survivrez-vous ? Maîtrisez votre arsenal et devenez le survivant ultime !
- 2

The Roc
Single-player alternative to Patient 0 — playable solo, no multiplayer required. Shares Action and Indie with Patient 0.
Venture into the dark realm of the legendary Roc, Run from cover to cover, Be wary of wild beasts and supernatural terrors and use your hand cannon if you have to, Find all ancient tablets and put an end to the Roc's Tyranny.
- 3

SCP: Contain and Extract
Single-player alternative to Patient 0 — playable solo, no multiplayer required. Shares Action with Patient 0.
A horror extraction shooter/creature collector unfolding in an overrun 1990s Site-19, built on rich SCP lore. Contain, extract and collect all the SCPs while surviving the evil that lurks throughout the site. Locate data, study ways to lure and trap, loot what you can and always be ready...
- 4

SCP
Single-player alternative to Patient 0 — playable solo, no multiplayer required. Shares Action and Indie with Patient 0.
Infiltrate breached SCP facilities in this tactical co-op horror extraction shooter. Survive surreal anomalies, recover forbidden intel, and escape.. or lose everything. The deeper you go, the stranger and deadlier it gets.
- 5

Strike Team Delta
Single-player alternative to Patient 0 — playable solo, no multiplayer required. Shares Action with Patient 0.
Strike Team Delta is a gripping first-person shooter set in a post-apocalyptic world. Battle hordes of undead, team up with friends, and reclaim our world. Survival is in your hands.
- 6

The Abandoned Levels
Single-player alternative to Patient 0 — playable solo, no multiplayer required. Shares Indie and Adventure with Patient 0.
After personal tragedy, you fall into the nightmarish Backrooms. Navigate handcrafted levels, evade deadly creatures, and cling to your sanity. Find the exit – and the answer to whether survival is worth the struggle at all.
- 7

Zombie Ship
Single-player alternative to Patient 0 — playable solo, no multiplayer required. Shares Action and Indie with Patient 0.
A first-person survival horror where a dying man becomes something that should not exist. Trapped aboard a cursed ship, fight through zombies, uncover the Boss's experiments, and discover what you've become.
- 8

Inner Demons
Single-player alternative to Patient 0 — playable solo, no multiplayer required. Shares Action and Indie with Patient 0.
Inner Demons is a first-person psychological horror game where the line between madness and reality dissolves. Explore, fight, and evade disturbing manifestations of your own mind as they invade the world around you - if you can tell them apart from what is real.