Single-player games like Immunity Protocol
Below are 8 single-player Steam games similar to Immunity Protocol, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Immunity Protocol page.
Ranked picks
- 1
Chain of Command
Single-player alternative to Immunity Protocol — playable solo, no multiplayer required. Shares Action and Indie with Immunity Protocol.
Chain of Command is a top-down arena shooter roguelike, where you control a snake-like chain of fighters that attack automatically. Choose your Commander and build your party to create high-synergy builds to crush the invading demon armies.
- 2
Forecast Death
Single-player alternative to Immunity Protocol — playable solo, no multiplayer required. Shares Action and Indie with Immunity Protocol.
Survive the chaos of a bullet-heaven action game. Tear through enemy hordes, stack wild ability combos, and endure cataclysms that rewrite the rules mid-fight. The pace ramps up every minute - either you grow stronger, or you get wiped out.
- 3
Micron Survivor
Single-player alternative to Immunity Protocol — playable solo, no multiplayer required. Shares Action with Immunity Protocol.
Micron Survivor is a survival game with rogue-lite elements where you play as alien microorganisms under the microscope. Evolve, unlock research objectives, find symbiotic weapons, upgrade your builds, and fight hordes of terrestrial organisms to rule the microcosm.
- 4
Orbit Run
Single-player alternative to Immunity Protocol — playable solo, no multiplayer required. Shares Action and Indie with Immunity Protocol.
Orbit Run is an arcade sci-fi game with roguelike elements, in which orbiting asteroids are your only weapons. Catch asteroids and combine them to unlock their run-altering abilities. Skillfully manoeuvre to dodge attacks and land massive asteroid strikes to defeat the ever-increasing waves of foes.
- 5
Nano Squadron
Single-player alternative to Immunity Protocol — playable solo, no multiplayer required. Shares Action and Indie with Immunity Protocol.
Manage your shields, evolve your ship, defend Earth. Nano Squadron is a top-down space roguelite where every run brings new upgrades and every mistake leaves you exposed.
- 6
Steel Swarm: SURVIVOR
Single-player alternative to Immunity Protocol — playable solo, no multiplayer required. Shares Action and Indie with Immunity Protocol.
Steel Swarm: SURVIVOR is a fast-paced roguelite survivors game where you obliterate swarms with your drones. Set up formations, upgrade your drones, and overwhelm hordes of metal in each run. Take on enemy waves solo or in multiplayer co-op!
- 7
Let Them Come: Onslaught
Single-player alternative to Immunity Protocol — playable solo, no multiplayer required. Shares Action with Immunity Protocol.
Survive the relentless offensive of the alien horde in Let Them Come: Onslaught, a sci-fi survival roguelite. The pursuit of the perfect build and an ever-expanding arsenal of abilities are the keys to your success.
- 8
Rhythm Storm
Single-player alternative to Immunity Protocol — playable solo, no multiplayer required. Shares Action with Immunity Protocol.
Rhythm Storm is a roguelike bullet heaven with stunning vector graphics, rhythmic action, and overwhelming swarms of enemies. Your vehicle aims and fires freely while everything else dances and moves to the beat in this spectacular audio-visual experience.