Single-player games like Mycelium Conquest: Mitosis
Below are 8 single-player Steam games similar to Mycelium Conquest: Mitosis, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Mycelium Conquest: Mitosis page.
Ranked picks
- 1
Mycelium Conquest
Single-player alternative to Mycelium Conquest: Mitosis — playable solo, no multiplayer required. Shares Strategy and Indie with Mycelium Conquest: Mitosis.
A deep biological network automation game where you grow a living mycelial network across an alien planet. Consume the local flora and creatures, build biological production chains, and evolve from a tiny spore into a cosmic entity that consumes worlds.
- 2
Belts of Iron
Single-player alternative to Mycelium Conquest: Mitosis — playable solo, no multiplayer required. Shares Strategy and Indie with Mycelium Conquest: Mitosis.
Explore, automate, and fight in this new open world factory automation game. Build factories connected by miles of conveyor belts. Manage power and fluid networks. Explore procedurally generated worlds filled with resources to harvest and hostile creatures to defeat. Play solo or online with friends
- 3
Settletopia
Single-player alternative to Mycelium Conquest: Mitosis — playable solo, no multiplayer required. Shares Strategy and Simulation with Mycelium Conquest: Mitosis.
Grow a small colony into a vast, world-spanning civilization. Play solo or with friends as you gather resources, build cities, manage colonist needs, explore uncharted lands, establish logistics, raise armies, forge alliances, and wage wars—all in a living world.
- 4
Per Aspera
Single-player alternative to Mycelium Conquest: Mitosis — playable solo, no multiplayer required. Shares Strategy and Indie with Mycelium Conquest: Mitosis.
Make Mars your own! Take control of the world’s most sophisticated AI (AMI) and terraform the surface of the Red Planet for a city-building experience on a planetary scale. Transform this barren world into a lush paradise and explore the surface for any ancient secrets that may be waiting.
- 5
Train Valley World
Single-player alternative to Mycelium Conquest: Mitosis — playable solo, no multiplayer required. Shares Strategy and Indie with Mycelium Conquest: Mitosis.
Train Valley World is an engrossing transport tycoon inspired by the genre classics. Build and manage efficient railroads across the globe, create sophisticated logistics chains, design your own levels, and become a business mogul – solo or in multiplayer!
- 6
Oddsparks: An Automation Adventure
Single-player alternative to Mycelium Conquest: Mitosis — playable solo, no multiplayer required. Shares Strategy and Indie with Mycelium Conquest: Mitosis.
Oddsparks is a blend of automation and real-time strategy for both the die-hard fans of the automation genre and the automation-curious. Explore a strange fantasy world, uncover the mysteries of the past, automate your workshops, and go on adventures with your odd & adorable Sparks!
- 7
Techtonica
Single-player alternative to Mycelium Conquest: Mitosis — playable solo, no multiplayer required. Shares Strategy and Indie with Mycelium Conquest: Mitosis.
Techtonica is a first-person factory automation game with a gripping mystery about mining your way out from the depths of an alien planet. Explore bioluminescent caves, mold destructible terrain, construct a massive subterranean factory. Dig your way toward answers & discover the secrets of Calyx.
- 8
Alchemy Factory
Single-player alternative to Mycelium Conquest: Mitosis — playable solo, no multiplayer required. Shares Strategy and Indie with Mycelium Conquest: Mitosis.
Craft your workshop as an alchemist! Harness arcane devices to automate crafting. Sell alchemical goods, fulfill commissions, and rise to become a renowned alchemy magnate. Multiplayer Supported! Invite master designers to (ahem) contribute their expertise—let them optimize your production lines!