Single-player games like STARPHAGE: Galactic Plague Simulator
Below are 8 single-player Steam games similar to STARPHAGE: Galactic Plague Simulator, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like STARPHAGE: Galactic Plague Simulator page.
Ranked picks
- 1

Alien Madness
Single-player alternative to STARPHAGE: Galactic Plague Simulator — playable solo, no multiplayer required. Shares Strategy and Indie with STARPHAGE: Galactic Plague Simulator.
Turn humans into idiots and make them kill each other!
- 2

Kindling Wilds: Symbiotic Wasteland
Single-player alternative to STARPHAGE: Galactic Plague Simulator — playable solo, no multiplayer required. Shares Strategy and Indie with STARPHAGE: Galactic Plague Simulator.
Ember: Symbiotic Wilderness is a 2D pixel-art co-op survival game set in a living wilderness shaped by temperature, weather, seasons, and ecology. Start with a single fire, divide the work with your team, and build a camp that can endure.
- 3

Helion Conflict
Single-player alternative to STARPHAGE: Galactic Plague Simulator — playable solo, no multiplayer required. Shares Strategy and Indie with STARPHAGE: Galactic Plague Simulator.
Real-time strategy stripped to the decision. Every factory you hold builds without pause - you choose where those ships go, and can turn them in mid-flight. Commander mode adds the war economy: iron and gold networks, turrets, satellites, orbital strikes. Up to eight online.
- 4

Cosmic Cult
Single-player alternative to STARPHAGE: Galactic Plague Simulator — playable solo, no multiplayer required. Shares Strategy and Indie with STARPHAGE: Galactic Plague Simulator.
Cosmic Cult is a roguelike deckbuilder where you're a fledgling god in a dying universe. Assemble the perfect deck of symbols to balance production of metal, faith, and power— or go all in on a single resource. Lead your cult in building a monument to outlast time itself, and make your own luck!
- 5

Plague Inc: Evolved
Single-player alternative to STARPHAGE: Galactic Plague Simulator — playable solo, no multiplayer required. Shares Strategy and Indie with STARPHAGE: Galactic Plague Simulator.
Plague Inc: Evolved is a unique mix of high strategy and terrifyingly realistic simulation. Your pathogen has just infected 'Patient Zero' - now you must bring about the end of human history by evolving a deadly, global Plague whilst adapting against everything humanity can do to defend itself.
- 6

Shotgun Rogue
Single-player alternative to STARPHAGE: Galactic Plague Simulator — playable solo, no multiplayer required.
Shotgun Rogue is a fast-paced roguelite where you defend your home from waves of enemies. Upgrade weapons, build turrets and traps, and unlock passive abilities each round. Create powerful combos, fortify your base, and survive as long as you can.
- 7

After Inc: Revival
Single-player alternative to STARPHAGE: Galactic Plague Simulator — playable solo, no multiplayer required. Shares Strategy and Simulation with STARPHAGE: Galactic Plague Simulator.
Can you rebuild civilisation after a zombie apocalypse? From the creator of Plague Inc. comes a unique blend of strategic simulation, survival city builder and ‘mini 4X’. Build settlements, harvest resources and shape society as you lead Humanity out of the darkness.
- 8

Astro Protocol
Single-player alternative to STARPHAGE: Galactic Plague Simulator — playable solo, no multiplayer required. Shares Strategy with STARPHAGE: Galactic Plague Simulator.
Astro Protocol is a high-stakes, turn-based 4X space strategy game distilled into intense one-hour matches. Six factions, randomized maps, tech trees, and anomalies ensure every run is unique. Victories are earned against challenging opponents that play to win.