Single-player games like Diseased
Below are 8 single-player Steam games similar to Diseased, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Diseased page.
Ranked picks
- 1

Hellcrown
Single-player alternative to Diseased — playable solo, no multiplayer required. Shares Strategy and Adventure with Diseased.
You are dead. But your ghostly hand still commands. Hellcrown is a roguelite strategy game where every run unfolds into a chain of random stories, sieges, and consequences.
- 2

Kingdom III: Rising Realms
Single-player alternative to Diseased — playable solo, no multiplayer required. Shares Strategy and Indie with Diseased.
Protect your crown! Kingdom returns in an all-new micro-strategy and tower defense game set in a shattered realm. Embark on an atmospheric adventure across lands of legend to build a lasting legacy and challenge the empowered Greed threat.
- 3

Corsair Cove
Single-player alternative to Diseased — playable solo, no multiplayer required. Shares Strategy and Simulation with Diseased.
Build a sprawling pirate haven, raise a fleet to explore the high seas, and take on the Crown to keep the Age of Piracy alive! From ale to flintlock pistols, and from scallywags to swashbucklers, you’ll need to manage complex production chains and govern a rowdy crew to reign supreme over the seas!
- 4

Ascent of Ashes
Single-player alternative to Diseased — playable solo, no multiplayer required. Shares Strategy and Indie with Diseased.
A colony sim set in a post-apocalyptic dystopia. Build and defend your base. Manage your survivors. Engage raiders, aliens, Remnant soldiers and other factions in real-time-with-pause combat. Or use stealth to outwit them. Explore the massive world. Survive at all costs
- 5

Pax Autocratica
Single-player alternative to Diseased — playable solo, no multiplayer required. Shares Action and Indie with Diseased.
Build a grand totalitarian colony and personally storm roguelite battlefields with your soldiers. Shape citizens fears, loyalties, bonds, and feuds. Capture enemies, convert them into true believers. Sacrifice the weak. Feed the strong. Wield absolute power and make every life bend to your will.
- 6

Until We Die
Single-player alternative to Diseased — playable solo, no multiplayer required. Shares Action and Strategy with Diseased.
Until We Die is a side-scrolling strategy game about defending your base where you have to run around as Ivan, assign tasks to people, and fight mutants in the post-apocalyptic subway!
- 7

Monsters are Coming!
Single-player alternative to Diseased — playable solo, no multiplayer required. Shares Action and Strategy with Diseased.
Beware, Monsters are Coming! In this Tower-Survivor rogue-lite, you protect an ever-moving city from unrelenting hordes. Gather resources, fortify defences, and survive for as long as you can. Will you reach the Ark?
- 8

RimWorld
Single-player alternative to Diseased — playable solo, no multiplayer required. Shares Strategy and Indie with Diseased.
A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more.