Single-player games like Genome Fracture
Below are 8 single-player Steam games similar to Genome Fracture, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Genome Fracture page.
Ranked picks
- 1
Approaching Infinity Survivors
Single-player alternative to Genome Fracture — playable solo, no multiplayer required. Shares Action and Indie with Genome Fracture.
A Bullet-Heaven roguelike in the Approaching Infinity universe with both spaceship and away team missions. The exit of the galaxy's dominant races left a power vacuum that everyone wants to fill. Survive, pick a side, or kill'em all. No time to think when the horde's advancing.
- 2
Space Show edition 17
Single-player alternative to Genome Fracture — playable solo, no multiplayer required. Shares Action and Indie with Genome Fracture.
Space Show is an explosive space shoot’em up blending fast-paced arcade action with roguelite progression. Destroy waves of asteroids, battle enemy fleets, and defend Earth in an endless war where only survival… and glory matter!
- 3
Micron Survivor
Single-player alternative to Genome Fracture — playable solo, no multiplayer required. Shares Action with Genome Fracture.
Micron Survivor is a survival game with rogue-lite elements where you play as alien microorganisms under the microscope. Evolve, unlock research objectives, find symbiotic weapons, upgrade your builds, and fight hordes of terrestrial organisms to rule the microcosm.
- 4
WARLANCER - Armored Survivor
Single-player alternative to Genome Fracture — playable solo, no multiplayer required. Shares Action with Genome Fracture.
WARLANCER - Armored Survivor is a top down survivor shooter where you employ weapons within weapons to decimate hordes of enemies with multiple waves of firepower. Configure your mech with upgrades and randomly generated weapons to survive the relentless tide of alien invaders.
- 5
Lone Survivors
Single-player alternative to Genome Fracture — playable solo, no multiplayer required. Shares Action and Indie with Genome Fracture.
An objective-driven bullet heaven where twelve classes build absurd weapon synergies across shifting fantasy biomes. Raise the dead as a Necromancer, plow through enemies as a Knight, and more! Survive events, bosses, and campaign objectives, then chase endless leaderboard runs.
- 6
Cyber-Nanotech Horde Survivor
Single-player alternative to Genome Fracture — playable solo, no multiplayer required. Shares Indie with Genome Fracture.
Defend the system core in this fast-paced cybernetic roguelite! Fight a self-merging digital virus, decrypt firewall nodes for powerful real-time subroutines, and defeat giant boss kernels. Spend credits on persistent hardware upgrades to survive the endless purge.
- 7
Nightveld
Single-player alternative to Genome Fracture — playable solo, no multiplayer required. Shares Indie with Genome Fracture.
A bullet heaven (a reverse bullet hell) where your only weapon is the light you see with. Widen the beam to see the swarm coming, or focus it to burn what's close, and go blind everywhere else. Survive to dawn, pick a power, and face a longer, hungrier Night. How many can you last?
- 8
NULL VECTOR
Single-player alternative to Genome Fracture — playable solo, no multiplayer required. Shares Action and Indie with Genome Fracture.
Defend a central core in a neon geometric survival tower defense. Move and aim your operator, construct fortifications, research permanent upgrades, collect enemy ability modules, face evolving bosses, unlock endless mode, or cooperate online with up to four players.