Single-player games like Genomino
Below are 9 single-player Steam games similar to Genomino, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Genomino page.
Ranked picks
- 1

Shorted
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Strategy and Indie with Genomino.
SHORTED is a puzzle roguelike deckbuilder about tracing same-color Packets into scoring shapes. Tune your deck, combine rule-bending Patches, and break through six hostile Firewalls.
- 2

Double Skunk
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Strategy and Indie with Genomino.
Cribbage played straight, with a roguelite engine on top: 57 powerups, 26 rank-card consumables, 10 pegs that rewrite the run. Game modes to spice things up. Take on a 21+rival campaign, enjoy offline at four skill tiers, or play online with ranked matches and a weekly challenge on one shared deal.
- 3

Laurus
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Strategy and Indie with Genomino.
Rig the machine until it pays out wrong. Draw symbols from your bag across five reels, chain paylines, and slot circuit-board artifacts into combos the house never accounted for. A roguelike deckbuilder about the arithmetic of very bad odds.
- 4

Pokermancer
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Strategy and Indie with Genomino.
A roguelike deckbuilder where poker hands are scored on a grid, not played from a hand. Link neighboring cards across a 4x4 grid into pairs, straights and flushes, then slide, swap and delete cards to bypass hazards that block the paths you need.
- 5

Killing Momentum: Umbral Moon
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Strategy with Genomino.
You are the commander, and your choices define your fate. Lead warriors on a perilous journey under the ghastly Umbral Moon. Defeat brutal enemies in tactical combat where momentum is everything. Brave deadly narrative encounters and manage the volatile bonds of your team of misfits to survive.
- 6

Dynamine
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Strategy with Genomino.
Dynamine is an incremental mining game based on Minesweeper. Dig for ores while avoiding explosives, sell what you found, buy better tools to dig more efficiently, then rinse and repeat!
- 7

DexSweeper
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Strategy and Indie with Genomino.
In DexSweeper, the cursor never stops moving. Use the joystick or mouse to guide your movement, then time your tile reveals carefully--one wrong move could be your last!
- 8

Facelet
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Strategy and Indie with Genomino.
Facelet is a roguelike deckbuilder played on a scrambled puzzle cube. Twist layers to line up colors, cash them in, and build a deck that scores a cube nobody would ever finish. Spend your winnings on Algorithms, Mods, stickers and Tools, then take the bigger cube into the next Depth.
- 9

MolEconomy
Single-player alternative to Genomino — playable solo, no multiplayer required. Shares Indie with Genomino.
Build an underground mole empire from the ground down! Mine resources, craft alloys, and trade products in a dynamic market. Expand your colony with research center, school, and more in this cozy yet complex economic sim.