Single-player games like Doc, I Don't Want to Die! Slice the Infection
Below are 9 single-player Steam games similar to Doc, I Don't Want to Die! Slice the Infection, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Doc, I Don't Want to Die! Slice the Infection page.
Ranked picks
- 1

Mega City Force
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Action and Indie with Doc, I Don't Want to Die! Slice the Infection.
Retrowave Action Roguelike featuring tough agents battling crime to the electrifying music of artists like Droid Bishop, Timecop1983, and more! Choose your agent and dive into hardcore action against enemies and bosses, utilizing a vast arsenal and special abilities that will define your playstyle
- 2

AIRHEART - Tales of broken Wings
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Action and Indie with Doc, I Don't Want to Die! Slice the Infection.
Airheart is a dieselpunk airplane action rogue like game, where every colorful level is built on top of the previous one, all the way up to the stratosphere. Welcome to Granaria, a flying city in the clouds. Meet Amelia - a young pilot and fisherwoman wishing to reach the abundant world's edge.
- 3

Blacksea Odyssey
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Action and Indie with Doc, I Don't Want to Die! Slice the Infection.
Enter the Blacksea Odyssey, a violent top-down rogue-lite space shoot ‘em up RPG brimming with colossal creatures and runic technologies. Explore dangerous, interstellar spacescapes as you hunt enormous space-behemoths with a harpoon and rune-infused spears.
- 4

Rush Rover
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Action and Indie with Doc, I Don't Want to Die! Slice the Infection.
Rush Rover is a 2D top-down shooter game. Compared to other similar games of the genre, the shooting experience is closer to traditional shoot'em up games. It includes random map generation, unique weapons, lots of different enemies, exciting boss battles and a dynamic chiptune soundtrack.
- 5

Peace Data
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Action and Indie with Doc, I Don't Want to Die! Slice the Infection.
Peace Data — hard "Roguelike" game, in which you have to play for Bitard, saving Rusland from the tyranny of the authorities that destroyed the opposition and led the country to ruin, making slaves of citizens.
- 6

Woodpunk
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Action and Indie with Doc, I Don't Want to Die! Slice the Infection.
Woodpunk is an exhilarating roguelike bullet hell retro pixel art shooter in a medieval Woodpunk universe, where the primary energy resource is WOOD.
- 7

God's Trigger
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Action and Indie with Doc, I Don't Want to Die! Slice the Infection.
Slay enemies with speed and precision in an over-the-top show of blood and explosions. Play solo or with others, make split-second decisions, dodge bullets, and use weapons and abilities to inflict violence in the most graphic way possible.
- 8

#KILLALLZOMBIES
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Action and Indie with Doc, I Don't Want to Die! Slice the Infection.
#KILLALLZOMBIES is an insane twin-stick zombie shooter with Twitch streaming interactions, where you survive hordes of zombies on a dynamically changing arena and spectators may affect gameplay via special Twitch chat commands.
- 9

Yukinite Depths
Single-player alternative to Doc, I Don't Want to Die! Slice the Infection — playable solo, no multiplayer required. Shares Indie with Doc, I Don't Want to Die! Slice the Infection.
Send a team of autonomous goblin miners deep underground in search of the legendary Yukinite crystal in this relaxing pixel-art incremental strategy game with idle elements. Discover rare resources, unlock powerful upgrades, expand your mine, and face whatever is waiting below.