Single-player games like Pharmakon - Tactical Puzzle
Below are 12 single-player Steam games similar to Pharmakon - Tactical Puzzle, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Pharmakon - Tactical Puzzle page.
Ranked picks
- 1
Rogue Waters
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required.
Rogue Waters is a Pirate Tactical Turn-Based Rogue-lite. Play as Captain Cutter, commanding your ship and crew through procedurally generated encounters to seek revenge. Recruit, train, and upgrade crew, use powerful sea creatures, and engage in dynamic naval and melee combat to gain the upper hand.
- 2
Flotilla
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
Lead your orbital battleships to victory in Flotilla! Fight, trade, and explore new planets in your journey through the galaxy. Featuring tactically rich 3D combat, flank and surprise the enemy from any direction. When the dust settles, generate another randomized universe for a brand new adventure!
- 3
Monster Train
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required.
Monster Train is a strategic roguelike deck building game with a twist. Set on a train to hell, you’ll use tactical decision making to defend multiple vertical battlegrounds. With real time competitive multiplayer and endless replayability, Monster Train is always on time.
- 4
Into the Breach
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
Control powerful mechs from the future to defeat an alien threat. Each attempt to save the world presents a new randomly generated challenge in this turn-based strategy game.
- 5
Bionic Dues
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
Bionic Dues is a tactical, turn-based roguelite with mech customization. Out-think wide-ranging tactical situations featuring robots with bad GPS, terrible aim, insecurity, a lack of focus, a tendency to backstab, and dozens of other maladies to exploit.
- 6
Astrea: Six-Sided Oracles
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
Astrea is a DICE-deck-building roguelike that flips the script on deckbuilders by using dice instead of cards and a unique dual “damage” system: Purification vs Corruption. Build a dice pool strong enough to purify Astrea's out-of-control corruption and save the Star System.
- 7
Othercide
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
As Humanity’s last hope, lead your army to combat in an intricate dance of spectacular actions and counters, using an original Dynamic Timeline System, and face fearsome bosses in epic battles.
- 8
Crowntakers
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
Crowntakers combines turn-based strategy with RPG elements and takes you at the behest of the crown into a medieval fantasy world full of challenging encounters and epic adventures. With its randomly generated world, Crowntakers offers a varied gaming experience every time you set out to fight evil.
- 9
Puyo Puyo™Tetris®
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required.
Two puzzle game juggernauts collide as global phenomenon Tetris® and SEGA’s famous Puyo Puyo™ combine in a super mash-up of ferocious competition, adorable looks, and addictive puzzle fun!
- 10
ANIME TETRIS
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
The legendary game "Tetris" in a unique performance and atmosphere
- 11
Volt Patrol - Stealth Driving
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
Become a stealth driver and try to evade the Volt Patrol security system!
- 12
Messticulous
Single-player alternative to Pharmakon - Tactical Puzzle — playable solo, no multiplayer required. Shares Indie with Pharmakon - Tactical Puzzle.
Aim and throw incongruous objects to create an organized mess by following the directives of a completely wacky "tidy up" system!