Single-player games like Pestis
Below are 9 single-player Steam games similar to Pestis, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Pestis page.
Ranked picks
- 1
Before I Turn: Survival Auto Battler
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Indie and Simulation with Pestis.
You've been bitten. Hours before you turn. All you have left: a clock running out and a deserted hospital lab. Identify the virus, synthesize your antiviral, and test it. But every win teaches it to resist you. Before I Turn blends survival, auto battler and simulation into one experience.
- 2
Propa.
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Simulation with Pestis.
In this RTS game, control your virus to replicate and evolve against a powerful immune system. Equip gene segments to create unique viral armies. Use tactics to eliminate immune cells or achieve escape. Develop strategies for domination and enjoy endless strategic fun!
- 3
Backrooms: Partygoers
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Indie and Simulation with Pestis.
Backrooms: Partygoers is a backrooms horror game based on Level 0 where you play as a researcher tasked to find anomalies inside the backrooms. You are equip with devices that can beep whenever an anomaly is near, where the partygoers roam and can hear you.
- 4
Ministry of Pandemic
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Indie and Simulation with Pestis.
Ministry of Pandemic is a strategy and simulation game that forces social and economic balance during the pandemic. Formulate your strategy for survival while keeping all aspects of society steady.
- 5
Covid Simulator
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Indie and Simulation with Pestis.
COVID SIMULATOR is an outbreak simulation that visualizes how quickly Covid-19 spreads, becoming a disaster. The game is an open sandbox where you can add (or remove) Covid mandates and see what happens! Create your workplace, enact your mandates, and roll the dice with your workers.
- 6
Salty: Evolution Simulator
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Simulation with Pestis.
A lone spark of life, one fragile cell adrift in a vast, chaotic world. Feed, grow, adapt, outmaneuver predators, survive viral invasions, and assemble new organelles that reshape your abilities and your destiny. You're learning the science the whole time, too immersed in survival to notice.
- 7
Herbalist Roman
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Simulation with Pestis.
Step into the role of a medieval herbalist. Study your herbal book, craft macerations, and help your clients by easing their ailments. Christianity is reaching the Slavic village of Drebor, and your choices will determine whether these changes unfold in peace.
- 8
Plague Doctor: Medieval Apothecary
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Indie and Simulation with Pestis.
In a city where death lingers in the air, you are the last one who can resist it. Put on the plague doctor’s mask and fight the plague before it reaches you.
- 9
Temptation
Single-player alternative to Pestis — playable solo, no multiplayer required. Shares Indie and Simulation with Pestis.
Temptation - a game about a medieval priest who is suddenly possessed by a demon. Your goal is to perform an unusual ritual of exorcism to banish the demon from himself!