IMHO.

Games like Auto Immune

If Auto Immune is your kind of game, the closest matches are Kings & Savages, Decoherence and Insectum - Epic Battles of Bugs — picked from the ranked list below. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.

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About Auto Immune: A virus is attacking your cells, and its up to you to defend them! Buy and combine cells to assemble your immune response. Discover powerful synergies to overcome a constantly evolving enemy in this physics-based auto battler. Can you achieve IMMUNITY?

StrategyCasualEarly AccessWindowsby Distant Signal Games
Auto Immune — Steam game cover

Players who liked Auto Immune also play

Steam players who put hours into Auto Immune also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.

  1. Kings & Savages

    WHY THIS

    Top pick for Auto Immune fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Early Access with Auto Immune.

    A fast-paced, high skill Solo/Auto-Battler. Easy to learn, hard to master. Inspired by Chess and Dota.

    2026ActionStrategyIndieSteam ↗
  2. Decoherence

    WHY THIS

    Second-strongest match for Auto Immune fans by collaborative filtering across millions of Steam libraries. Shares Strategy with Auto Immune.

    Build robots, devise a battle plan and fight alongside them!

    2021ActionStrategyIndieFreeSteam ↗
  3. Insectum - Epic Battles of Bugs

    WHY THIS

    Third-strongest match for Auto Immune fans by collaborative filtering across millions of Steam libraries. Shares Strategy with Auto Immune.

    Immerse yourself in the epic battles of "Insectum" and unleash the power of your monstrous insects. Face off against your rivals on the battlefield by strategically using cards.

    2024ActionStrategy9.99 USDSteam ↗
  4. SolForge Fusion

    WHY THIS

    Ranked #4 for Auto Immune fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Casual with Auto Immune.

    SolForge Fusion is a collectible card-battler where you are a mighty Forgeborn. Command fierce creatures, cast powerful spells, level up your cards, and crush your foes to earn glorious rewards. Created by Richard Garfield (Magic: The Gathering) and Justin Gary (Ascension).

    2024StrategyIndieFree To PlayFreeDeck PlayableSteam ↗
  5. Wireworks

    WHY THIS

    Ranked #5 for Auto Immune fans by collaborative filtering across millions of Steam libraries. Shares Strategy with Auto Immune.

    Design your defenses, build your module board, and manage your wires. Combine signals and create synergies to empower your weapons and survive in this base-defense roguelike auto-battler.

    2026StrategyIndieSimulation5.59 USDDeck VerifiedSteam ↗
  6. Loopstructor

    WHY THIS

    Ranked #6 for Auto Immune fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Casual with Auto Immune.

    This is a strategy game that combines tower defense with Roguelike. Unlike traditional tower defense game, the towers in the game are vehicles that move along ‘loops’.You need to create defense loop and build battle trains to defend against enemy attacks.

    2024StrategyIndieCasual2.49 USDSteam ↗
  7. Godslayer Arena

    WHY THIS

    Ranked #7 for Auto Immune fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Early Access with Auto Immune.

    Godslayer Arena is a roguelike fusion of autobattlers and action-rpgs. Combat is performed completely automatically. Understanding complex interactions between the spells, gems, and items you draft will be key to success. Break the game. Become overpowered.

    2025ActionStrategyEarly Access14.99 USDDeck PlayableSteam ↗
  8. Turnbound

    WHY THIS

    Ranked #8 for Auto Immune fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Early Access with Auto Immune.

    Turnbound is an auto battler, where you manage a hero's inventory to escape a haunted boardgame. Each run is different from the last, with unique upgrades, combos and synergies. Async PvP lets you battle the ghosts of other players at your own pace in this unique new inventory battler.

    2026StrategyIndieEarly Access14.99 USDDeck VerifiedSteam ↗

Free alternatives

Free-to-play games that recommended players of this title also tend to enjoy.

  1. Bongo Cat

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    Bongo cat needs your help. Bongo cat needz more hatz!!! Every time you press a key, Bongo cat will punch your taskbar. Type, click, play, work to collect more points. Which hats will you find?

    2025IndieSimulationMassively MultiplayerFreeDeck PlayableSteam ↗
  2. Indigo Park: Chapter 1

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    Explore the abandoned childhood wonder of Indigo Park! Guided by Rambley the Raccoon, help restore power to the destroyed amusement park while you run from the reason it shut down.

    2024ActionIndieAdventureFreeDeck PlayableSteam ↗
  3. STRAFTAT

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    STRAFTAT is a 1v1/2v2 ONLINE first person SHOOTER with quick rounds in over 350 MAPS ; Including all WEAPONS, proximity chat and 4 players FFA.

    2024ActionFreeDeck PlayableSteam ↗
  4. Awaria

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    Awaria is a short game about working in haunted maintenance tunnels.

    2024ActionIndieFree To PlayFreeDeck PlayableSteam ↗
  5. The Expendabros

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    The Expendabros have assembled and set their sights on the forces of ruthless arms dealer Conrad Stonebanks in the forests of Eastern Europe.

    2014ActionIndieAdventureFreeDeck VerifiedSteam ↗
  6. Steam Engine Simulator

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    The Steam Engine Simulator shown on AngeTheGreat's YouTube channel.

    2023SimulationFreeDeck VerifiedSteam ↗
  7. Iron Snout

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    Iron Snout is a fast, colorful and brutal fighting game in which you will be helping a piglet fight for its life against hordes of wolves.

    2016ActionIndieFree To PlayFreeDeck PlayableSteam ↗
  8. Magic Archery

    WHY THIS

    Free-to-play pick from the same recommendation pool — no purchase to try it.

    Train a commoner to become the greatest archer in this short incremental game! Increase your stats, gather wealth from quests, buy upgrades, and infuse your arrows with magic.

    2024IndieSimulationRPGFreeDeck PlayableSteam ↗

Frequently asked about Auto Immune

Does Auto Immune have multiplayer or co-op?
Yes — Auto Immune supports multi-player play according to its Steam store listing (Multi-player).
What games are most similar to Auto Immune?
Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Auto Immune are Kings & Savages, Decoherence, Insectum - Epic Battles of Bugs.
Who developed Auto Immune?
Auto Immune was developed by Distant Signal Games.

imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on Auto Immune.

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16 Games Like Auto Immune — Ranked for 2026 · imho.run