Games like Ex Vitro
If Ex Vitro is your kind of game, the closest matches are BIOMORPH, DOOMBLADE and Quarion — picked from the ranked list below. Reviewers single out its color coded weapon upgrades, atmospheric and dark. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.
Get personalized picks →About Ex Vitro: EX VITRO is a dark sci-fi 2D platformer where you delve into the ruins of a military research facility and discover the horrors within. Whether machine, creature, or something else entirely, you’ll face the violent legacy of the last survivors of humanity.

Players who liked Ex Vitro also play
Steam players who put hours into Ex Vitro also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.
BIOMORPH
WHY THIS
Shares environmental puzzle solving and an atmospheric mood with Ex Vitro.
Top pick for Ex Vitro fans by collaborative filtering across millions of Steam libraries. Shares Action and Adventure with Ex Vitro.
BIOMORPH is a dark metroidvania game where you become the creatures that you kill! Solve ingenious puzzles and navigate a stunning hand-drawn world. Meet quirky characters, rebuild a city, and uncover the secrets of a sprawling, fallen civilization… and of your own mysterious origins.
DOOMBLADE
WHY THIS
Shares multiple endings and an atmospheric mood with Ex Vitro.
Second-strongest match for Ex Vitro fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Ex Vitro.
Deep underground, Gloom Girl discovers DOOMBLADE, a sentient weapon hellbent on escape after eons in chains. Together, “Doom and Gloom” embark on a vengeful quest to unlock the powerful abilities and destroy the Dread Lords once and for all in this 2D Action Metroidvania.
Quarion
WHY THIS
Shares metroidvania exploration, checkpoint system, retro and an atmospheric mood with Ex Vitro.
Third-strongest match for Ex Vitro fans by collaborative filtering across millions of Steam libraries. Shares Indie and Adventure with Ex Vitro.
A short 2D pixel-style metroidvania where you explore, fight bosses, aquire items and abilities and find secrets. Inspired by games such as You Have to Win the Game and VVVVVV.
Mable & The Wood
WHY THIS
Ranked #4 for Ex Vitro fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Ex Vitro.
Hunt down massive beasts and, upon destroying them, shapeshift into their forms in order to use their powers to save or destroy the world. Players with less violent intent can find secret paths to complete Mable without killing anything, including bosses.
Derelict Star
WHY THIS
Shares exploration based progression, backtracking and atmospheric with Ex Vitro.
Ranked #5 for Ex Vitro fans by collaborative filtering across millions of Steam libraries. Shares Action and Adventure with Ex Vitro.
A precise momentum-based platformer that emphasizes exploration and navigation puzzles. Run and jump your way through a wide variety of obstacles and challenges as you explore an abandoned derelict freighter. Be careful: getting in is often easier than getting out!
ANIMAL WELL
WHY THIS
Shares hidden collectibles and an atmospheric mood with Ex Vitro.
Ranked #6 for Ex Vitro fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Ex Vitro.
Explore a dense, interconnected labyrinth, and unravel its many secrets. Collect items to manipulate your environment in surprising and meaningful ways. Encounter beautiful and unsettling creatures, as you attempt to survive what lurks in the dark. There is more than what you see.
Waking Mars
WHY THIS
Shares an atmospheric mood with Ex Vitro.
Ranked #7 for Ex Vitro fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Ex Vitro.
In 2097, life is discovered on Mars. When your mission of first contact becomes trapped by a cave-in, you must master the alien ecosystem to survive. Soon you stumble upon more than anyone expected, and with time running out, you will make a decision that determines the fate of a lost planet.
Recompile
WHY THIS
Shares data log collection and an atmospheric mood with Ex Vitro.
Ranked #8 for Ex Vitro fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with Ex Vitro.
This atmospheric, Metroidvania hacking adventure lets you take control of a semi-sapient program struggling against deletion. In the sprawling 3D world of a Mainframe, Recompile features intense combat, tight 3D platforming, super-powered abilities and an environmental logic-based hacking mechanic.
Reviewers mention these as similar to Ex Vitro
Surfaced from review text: when other players write 'if you liked X, try Y', we catch the name and resolve it back to a Steam game.
Mycocosm
WHY THIS
Reviewers of Ex Vitro cross-mention this title as a similar play. Shares Action with Ex Vitro.
MYCOCOSM is a casual arcade shooter and resource manager where you take the role of a newly sprouted seedling. Fight off waves of soil-borne enemies using antimicrobial chemicals, and trade for precious nutrients with wandering fungal spores - but beware their deceitful dealings.
Hollow Knight
WHY THIS
Shares exploration and an atmospheric mood with Ex Vitro.
Reviewers of Ex Vitro cross-mention this title as a similar play. Shares Action and Indie with Ex Vitro.
Forge your own path in Hollow Knight! An epic action adventure through a vast ruined kingdom of insects and heroes. Explore twisting caverns, battle tainted creatures and befriend bizarre bugs, all in a classic, hand-drawn 2D style.
A Robot Named Fight!
WHY THIS
Shares an atmospheric mood with Ex Vitro.
Reviewers of Ex Vitro cross-mention this title as a similar play. Shares Action and Indie with Ex Vitro.
A Robot Named Fight is a Metroidvania roguelike focused on exploration and item collection. Explore a different, procedurally-generated labyrinth each time you play and discover randomized power-ups to traverse obstacles, find secrets and explode meat beasts.
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Head-to-head comparisons
Plays great on Steam Deck
Valve-Verified or Playable picks from the similar pool — ready to go on Deck out of the box.
BIOMORPH
WHY THIS
Shares environmental puzzle solving and an atmospheric mood with Ex Vitro.
Deck Verified — runs on Steam Deck out of the box. Shares Action and Adventure with Ex Vitro.
BIOMORPH is a dark metroidvania game where you become the creatures that you kill! Solve ingenious puzzles and navigate a stunning hand-drawn world. Meet quirky characters, rebuild a city, and uncover the secrets of a sprawling, fallen civilization… and of your own mysterious origins.
ANIMAL WELL
WHY THIS
Shares hidden collectibles and an atmospheric mood with Ex Vitro.
Deck Verified — runs on Steam Deck out of the box. Shares Action and Indie with Ex Vitro.
Explore a dense, interconnected labyrinth, and unravel its many secrets. Collect items to manipulate your environment in surprising and meaningful ways. Encounter beautiful and unsettling creatures, as you attempt to survive what lurks in the dark. There is more than what you see.
Recompile
WHY THIS
Shares data log collection and an atmospheric mood with Ex Vitro.
Deck Verified — runs on Steam Deck out of the box. Shares Action and Indie with Ex Vitro.
This atmospheric, Metroidvania hacking adventure lets you take control of a semi-sapient program struggling against deletion. In the sprawling 3D world of a Mainframe, Recompile features intense combat, tight 3D platforming, super-powered abilities and an environmental logic-based hacking mechanic.
Frequently asked about Ex Vitro
- Does Ex Vitro run on Steam Deck?
- Ex Vitro is rated Playable on Steam Deck — it runs, but expect some manual adjustments (control remapping, text size, or graphics settings) for the best experience.
- Is Ex Vitro free to play?
- Yes — Ex Vitro is a free-to-play title on Steam. You can install and play it without buying anything, though some games include optional in-app purchases.
- What games are most similar to Ex Vitro?
- Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Ex Vitro are BIOMORPH, DOOMBLADE, Quarion.
- Who developed Ex Vitro?
- Ex Vitro was developed by Evolver Dynamics.
imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on Ex Vitro.
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