IMHO.

Single-player games like Chemical Combat

Below are 8 single-player Steam games similar to Chemical Combat, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Chemical Combat page.

Ranked picks

  1. 1
    Terralora — Steam game cover

    Terralora

    Single-player alternative to Chemical Combat — playable solo, no multiplayer required. Shares Action and Indie with Chemical Combat.

    Everything has gone to crap, you know your end will come soon enough, but you decide you’ll face your fears. Take on Beth’s final wish, set out to purify Aerlysia of all great demons, and seize the power of the Dreamstone.

    2025ActionIndieAdventure7.99 USDSingle-playerSimilar games →
  2. 2
    The Dungeon Persists — Steam game cover

    The Dungeon Persists

    Single-player alternative to Chemical Combat — playable solo, no multiplayer required. Shares Action and Indie with Chemical Combat.

    A top-down, pixel-art roguelike dungeon crawler. Pick one of 6 heroes and descend through an endless run of procedurally generated floors. Build a run from weapons, relics and gear, fight 24 enemy types and 4 bosses, and carry meta-progression forward. It was here before you. It will be here after.

    2026ActionIndieAdventure3.99 USDSingle-playerSimilar games →
  3. 3
    Roboholic — Steam game cover

    Roboholic

    Single-player alternative to Chemical Combat — playable solo, no multiplayer required. Shares Action and Indie with Chemical Combat.

    Roboholic is a thrilling Rogue-Lite FPS about robots and beer. Fast-paced gameplay inspired by Doom, with visuals akin to Borderlands. Wield powerful alco-guns, unleash unique abilities, and use the destructible environment to turn enemies into scrap. Bring the ultimate beer apocalypse to life!

    2021ActionIndieSingle-playerSimilar games →
  4. 4
    Curse of Deflection — Steam game cover

    Curse of Deflection

    Single-player alternative to Chemical Combat — playable solo, no multiplayer required. Shares Action and Indie with Chemical Combat.

    Curse of Deflection is an action roguelike where you bounce through a dungeon. Hit enemies with your weapons but watch out for where your trajectory leads next. Choose an adventurer and enter the dungeon to find loot and powerful weapons. Choose your build carefully because death comes at you fast.

    ActionIndieSingle-playerSimilar games →
  5. 5
    VOID/BREAKER — Steam game cover

    VOID/BREAKER

    Single-player alternative to Chemical Combat — playable solo, no multiplayer required. Shares Action and Indie with Chemical Combat.

    Fast paced Bullet hell Roguelite FPS 🔴 Fight relentless machines driven by a hostile AI. Escape an endless cycle. Craft infinite weapon variants with deep gun modding. Forge deadly synergies. Carve your way out through enviro destruction /BREAK THE SYSTEM /BREAK FREE

    2025ActionSportsIndie19.99 USDDeck VerifiedSingle-playerSimilar games →
  6. 6
    Cinderia — Steam game cover

    Cinderia

    Single-player alternative to Chemical Combat — playable solo, no multiplayer required. Shares Action and Indie with Chemical Combat.

    A fast, brutal action roguelite with razor-sharp controls and insane build freedom. Fuse embers, skill cards, and gear into wildly overpowered combat styles — and break each run in a world consumed by the Ash Witch.

    2026ActionIndieAdventure17.99 USDDeck VerifiedSingle-playerSimilar games →
  7. 7
    Genome Guardian 2 — Steam game cover

    Genome Guardian 2

    Single-player alternative to Chemical Combat — playable solo, no multiplayer required. Shares Action and Indie with Chemical Combat.

    COMBINE WEAPONS in the microscopic shooter with macroscopic depth. BUILD YOUR NANOBOT from hundreds of parts. SURVIVE the microbial onslaught once more in this psychedelic dive to the Abyss, full of mutations, minerals, anomalies and powerup polyps. SHMUP mode turns it into a vertical shoot 'em up!

    2026ActionIndieRPG15.99 USDDeck PlayableSingle-playerSimilar games →
  8. 8
    Deadly Days: Roadtrip — Steam game cover

    Deadly Days: Roadtrip

    Single-player alternative to Chemical Combat — playable solo, no multiplayer required. Shares Action and Indie with Chemical Combat.

    Loot, shoot, and mow down zombie hordes in this bullet heaven fever dream. Embark on a deadly roadtrip, fuel your bus, decide when to extract – and get that sweet inventory management kick when that new slot in your backpack fits just right.

    2025ActionIndieEarly Access9.74 USDDeck VerifiedSingle-playerSimilar games →