Single-player games like MUTAGEN
Below are 8 single-player Steam games similar to MUTAGEN, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like MUTAGEN page.
Ranked picks
- 1
InOut
Single-player alternative to MUTAGEN — playable solo, no multiplayer required. Shares Action and Indie with MUTAGEN.
A minimalist puzzle platformer where each level is more than they seem. Change your perspective on levels to discover new areas. Explore the world to unearth its hidden secrets.
- 2
There's Nothing Underground
Single-player alternative to MUTAGEN — playable solo, no multiplayer required. Shares Action and Indie with MUTAGEN.
There's Nothing Underground is a roguelike puzzle adventure where you use random tools to solve levels in endless ways. Unlock and combine tools to tackle 100+ levels, each with unique challenges. Find creative solutions, uncover the asteroid's secrets, and survive!
- 3
Polly's Puzzle Box
Single-player alternative to MUTAGEN — playable solo, no multiplayer required. Shares Indie with MUTAGEN.
As a small flea, explore a mysterious puzzle box filled with shapes and secrets. Gather strange items with hidden abilities, and unravel a trail of clues as you attempt to escape.
- 4
Relic Light
Single-player alternative to MUTAGEN — playable solo, no multiplayer required. Shares Indie with MUTAGEN.
A pixel-art 2D puzzle platformer with Metroidvania exploration. Join starfarer girl Ling Ao'ao as she meets AI girl ALICE in the ruins of humanity at the universe's end. Befriend companions, gather abilities, solve intricate contraptions, and uncover the cosmos's truth.
- 5
Nonolith
Single-player alternative to MUTAGEN — playable solo, no multiplayer required. Shares Indie with MUTAGEN.
The NONOLITH consumes you. Copy and paste the world around you to discover the secrets of this ancient, enigmatic structure. You are very powerful, you just don't know it yet.
- 6
MONOMOON
Single-player alternative to MUTAGEN — playable solo, no multiplayer required. Shares Indie with MUTAGEN.
In MONOMOON, the way forward is reserved for the knowing and the daring. Guided by moonlight, you’ll uncover hidden truths and wander through a tiny and mysterious open world.
- 7
Duat: Beyond Light & Shadow
Single-player alternative to MUTAGEN — playable solo, no multiplayer required. Shares Action and Indie with MUTAGEN.
The mystical Egyptian underworld beckons you in Duat: Beyond Light & Shadow! Foil the plans of Set and Apep using your powers of light. Explore the varied environments of the underworld and battle your way through in this epic pixel art style Metroidvania.
- 8
KON: Tale of the Darkness
Single-player alternative to MUTAGEN — playable solo, no multiplayer required. Shares Action and Indie with MUTAGEN.
A dark-fantasy interdimensional adventure. Snap your fingers to explore overlapping realities, face high-intensity platforming sections, solve environmental puzzles, and escape a deadly force threatening to consume everything.