Games like PROJECT M.E.D.S.
If PROJECT M.E.D.S. is your kind of game, the closest matches are NeuroSquad - Slay the Horde, E-Lich: Corporate Souls and One More Run — picked from the ranked list below. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.
Get personalized picks →About PROJECT M.E.D.S.: The body is under attack. Hordes of infectious germs are spreading rapidly, overwhelming its natural defenses. As the last line of defense, you'll battle through massive waves of pathogens, unlock powerful medical weapons, and fight to keep your host alive.

Players who liked PROJECT M.E.D.S. also play
Steam players who put hours into PROJECT M.E.D.S. also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.
NeuroSquad - Slay the Horde
WHY THIS
Top pick for PROJECT M.E.D.S. fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with PROJECT M.E.D.S..
Invent your own weapons in this sci-fi Roguelike shooter! Combine any weapon with any upgrade to customize your arsenal. Form a squad of holographic soldiers, redesign their guns too, and slay hordes of cybernetic enemies!
E-Lich: Corporate Souls
WHY THIS
Second-strongest match for PROJECT M.E.D.S. fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with PROJECT M.E.D.S..
There’s no R.I.P at E-Lich Corp! Explore the afterlife in this roguelite bullet heaven that is all about humor, insane power-levels, replayability and awful office jokes. Reap souls along your undead coworkers in a company that values your life. And death. Literally.
One More Run
WHY THIS
Third-strongest match for PROJECT M.E.D.S. fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with PROJECT M.E.D.S..
Dive into a world that blends frenetic roguelite action with deep systems and content-rich exploration. Explore densely populated maps to unlock the secrets of a fantasy world under siege by a mechanical threat.
ERLIK
WHY THIS
Ranked #4 for PROJECT M.E.D.S. fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with PROJECT M.E.D.S..
A Turkic folk-horror bullet-heaven roguelite. Every run drifts between two gods; feed Erlik's corruption for savage power and lifesteal, or rise toward Tengri's light for shields and renewal. Every weapon evolves down two opposed paths. Survive the Long Night.
Hell Maiden
WHY THIS
Ranked #5 for PROJECT M.E.D.S. fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with PROJECT M.E.D.S..
Traverse the depths of Hell and beat its toughest demons on your way to Heaven in this horde survival deck-building game inspired by Dante's Divine Comedy.
Arms of God
WHY THIS
Ranked #6 for PROJECT M.E.D.S. fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with PROJECT M.E.D.S..
Gear up for a battle through hell in this roguelite Bullet Heaven Arena Autoshooter with Doom-inspired gore vibes, metal music, and a satisfying combat feel. Wield five weapons at once, upgrade and merge them to forge indestructible builds, and bring divine justice to a world on the brink of chaos.
Nishin Difenda
WHY THIS
Ranked #7 for PROJECT M.E.D.S. fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with PROJECT M.E.D.S..
A chaotic 2D action roguelite where an egg cell guardian fights waves of Enemies, upgrades biological defenses, builds antibody turrets, and survives a ridiculous educational bullet heaven.
Order of Beast
WHY THIS
Ranked #8 for PROJECT M.E.D.S. fans by collaborative filtering across millions of Steam libraries. Shares Action and Indie with PROJECT M.E.D.S..
A dark fantasy top-down action roguelite survivor game. Choose an outcast hero, forge evolving skills, collect strange relics, and survive wave after wave until you face the old lords who still rule the ruins.
Free alternatives
Free-to-play games that recommended players of this title also tend to enjoy.
Life is Strange - Episode 1
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Action with PROJECT M.E.D.S..
Episode 1 now FREE! Life is Strange is an award-winning and critically acclaimed episodic adventure game that allows the player to rewind time and affect the past, present and future.
Indigo Park: Chapter 1
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Action and Indie with PROJECT M.E.D.S..
Explore the abandoned childhood wonder of Indigo Park! Guided by Rambley the Raccoon, help restore power to the destroyed amusement park while you run from the reason it shut down.
Sheepy: A Short Adventure
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Casual with PROJECT M.E.D.S..
A Short Handcrafted Pixel Art Platformer that follows Sheepy, an abandoned plushy brought to life. Sheepy: A Short Adventure is the first short game from MrSuicideSheep.
NGU IDLE
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with PROJECT M.E.D.S..
NGU Idle is a Free To Play Idle game that's full of weird humor, tons of upgrades and hundreds of hours of content! Try out NGU Idle today and experience the joy of Numbers Going Up!
Grimm's Hollow
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and RPG with PROJECT M.E.D.S..
A spooky, freeware RPG where you search the afterlife for your brother. Reap ghosts with your scythe, explore haunted caves, and eat ghostly treats on your journey through death.
The Expendabros
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Action and Indie with PROJECT M.E.D.S..
The Expendabros have assembled and set their sights on the forces of ruthless arms dealer Conrad Stonebanks in the forests of Eastern Europe.
Iron Snout
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Action and Indie with PROJECT M.E.D.S..
Iron Snout is a fast, colorful and brutal fighting game in which you will be helping a piglet fight for its life against hordes of wolves.
Narrow it down
Head-to-head comparisons
Frequently asked about PROJECT M.E.D.S.
- What games are most similar to PROJECT M.E.D.S.?
- Based on Steam play patterns and shared genres/tags, the games most often recommended alongside PROJECT M.E.D.S. are NeuroSquad - Slay the Horde, E-Lich: Corporate Souls, One More Run.
- Who developed PROJECT M.E.D.S.?
- PROJECT M.E.D.S. was developed by Fat Ghost Productions.
imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on PROJECT M.E.D.S..
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