Games like Total Synthesis
If Total Synthesis is your kind of game, the closest matches are Last Shinobi, Epic Action Packs and Sushiamo — picked from the ranked list below. Each pick is ranked by what players of this game also play, shared genres and tags, and review-mined similarity — not a generic popularity list.
Get personalized picks →About Total Synthesis: The complete organic chemistry study app: 1,000+ practice items, 28 flashcard decks, every mechanism step by step, and full mock exams — built for course exams, MCAT review, and post-bacc refreshers. The bonus: a real deckbuilding roguelike where the chemistry is the combat.
Players who liked Total Synthesis also play
Steam players who put hours into Total Synthesis also tend to own these titles — a signal called collaborative filtering. imho.run cross-references millions of library ownership patterns to surface games whose real audiences overlap, regardless of whether their genre tags match.
Last Shinobi
WHY THIS
Top pick for Total Synthesis fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with Total Synthesis.
Dive into a tactical roguelike where every decision counts. Build a unique strategy, unlock new skills and companions, and refine your synergies. Each level is a strategic puzzle to solve. No deck, minimal randomness, only strategic choices.
Epic Action Packs
WHY THIS
Second-strongest match for Total Synthesis fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with Total Synthesis.
Become a master of Deckscovery when you combine cards, build your Master Deck and defeat the Deck Master while avoiding elemental weaknesses!
Sushiamo
WHY THIS
Third-strongest match for Total Synthesis fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with Total Synthesis.
Sushiamo is a roguelike deck-builder where you make sushi to reach absurd scores. Discover unique ingredients, sauces, game-changing tools, and navigate the map to break the game with insane combos!
SURVIVAL ARCHIVE
WHY THIS
Ranked #4 for Total Synthesis fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with Total Synthesis.
In this world consumed by chaos, there is no savior. Only you and your cards—explore the vast world, encounter NPCs by chance, battle enemies, plant and harvest, and discover how to make tomorrow better.
Tic Card Toe
WHY THIS
Ranked #5 for Total Synthesis fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with Total Synthesis.
A Turn Based Strategy Roguelike with Deckbuilding elements that transforms Tic-Tac-Toe into a High-Stakes Combat Tournament!
Pokermancer
WHY THIS
Ranked #6 for Total Synthesis fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with Total Synthesis.
A roguelike deckbuilder where poker hands are scored on a grid, not played from a hand. Link neighboring cards across a 4x4 grid into pairs, straights and flushes, then slide, swap and delete cards to bypass hazards that block the paths you need.
Crystal Core
WHY THIS
Ranked #7 for Total Synthesis fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with Total Synthesis.
Crystal Core is a first-person roguelike deckbuilder where every card becomes an action in battle. Build your deck, choose your hero, and descend through the cursed Crystal Caves, battling monsters and growing stronger with every encounter. Can you survive the depths and destroy the Crystal Core?
Pelican Empyrean
WHY THIS
Ranked #8 for Total Synthesis fans by collaborative filtering across millions of Steam libraries. Shares Strategy and Indie with Total Synthesis.
A roguelike cooking card game about collecting magic artefacts to amplify your culinary powers! Share the magic of abundance by cooking delicious meals for all who come to Pelican's kitchen. Food is love!
Cheaper alternatives
Games in the same vein priced at least 40% below Total Synthesis at current Steam store prices.
Garry's Mod
WHY THIS
Priced ~50% under Total Synthesis on Steam right now. Shares Indie and Casual with Total Synthesis.
Garry's Mod is a physics sandbox. There aren't any predefined aims or goals. We give you the tools and leave you to play.
Vampire Survivors
WHY THIS
Priced ~50% under Total Synthesis on Steam right now. Shares Indie and Casual with Total Synthesis.
Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!
How to Fish
WHY THIS
Priced ~50% under Total Synthesis on Steam right now. Shares Indie and Casual with Total Synthesis.
A 1-4 player physics based fishing simulator. While drinking and boating you suddenly crash into a small island. To work your way back home you have to learn How to Fish.
Cookie Clicker
WHY THIS
Priced ~50% under Total Synthesis on Steam right now. Shares Strategy and Indie with Total Synthesis.
An idle game about making cookies! Originally released in 2013 on the web, and actively developed since then. This is the official version for Steam.
WEBFISHING
WHY THIS
Priced ~50% under Total Synthesis on Steam right now. Shares Indie and Casual with Total Synthesis.
WEBFISHING a multiplayer chatroom-focused fishing game! Relax and fish (on the web!)
POSTAL 2
WHY THIS
Priced ~90% under Total Synthesis on Steam right now. Shares Indie with Total Synthesis.
Live a week in the life of "The POSTAL Dude"; a hapless everyman just trying to check off some chores. Buying milk, returning an overdue library book, getting Gary Coleman's autograph, what could possibly go wrong?
Plants vs. Zombies GOTY Edition
WHY THIS
Priced ~50% under Total Synthesis on Steam right now. Shares Strategy with Total Synthesis.
Zombies are invading your home, and the only defense is your arsenal of plants! Armed with an alien nursery-worth of zombie-zapping plants like peashooters and cherry bombs, you'll need to think fast and plant faster to stop dozens of types of zombies dead in their tracks.
Buckshot Roulette
WHY THIS
Priced ~70% under Total Synthesis on Steam right now. Shares Indie with Total Synthesis.
Play Russian roulette with a 12-gauge shotgun. Four enter. One leaves. Roll the dice with your life. Good luck!
Free alternatives
Free-to-play games that recommended players of this title also tend to enjoy.
Bongo Cat
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with Total Synthesis.
Bongo cat needs your help. Bongo cat needz more hatz!!! Every time you press a key, Bongo cat will punch your taskbar. Type, click, play, work to collect more points. Which hats will you find?
Indigo Park: Chapter 1
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with Total Synthesis.
Explore the abandoned childhood wonder of Indigo Park! Guided by Rambley the Raccoon, help restore power to the destroyed amusement park while you run from the reason it shut down.
Sheepy: A Short Adventure
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Casual with Total Synthesis.
A Short Handcrafted Pixel Art Platformer that follows Sheepy, an abandoned plushy brought to life. Sheepy: A Short Adventure is the first short game from MrSuicideSheep.
Travellin Cats in Paris
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Casual with Total Synthesis.
Find 100 cats hidden in Paris, France in this cute hand-drawn hidden object game by Travellin Cats - the original viral hidden cat game creator!
Grimm's Hollow
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with Total Synthesis.
A spooky, freeware RPG where you search the afterlife for your brother. Reap ghosts with your scythe, explore haunted caves, and eat ghostly treats on your journey through death.
Virtual Cottage
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie and Casual with Total Synthesis.
Virtual Cottage gives you a comfy place to rest and be productive without any distractions. Open the game, set yourself a goal and enjoy the atmosphere.
Steam Engine Simulator
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it.
The Steam Engine Simulator shown on AngeTheGreat's YouTube channel.
Magic Archery
WHY THIS
Free-to-play pick from the same recommendation pool — no purchase to try it. Shares Indie with Total Synthesis.
Train a commoner to become the greatest archer in this short incremental game! Increase your stats, gather wealth from quests, buy upgrades, and infuse your arrows with magic.
Narrow it down
Head-to-head comparisons
Frequently asked about Total Synthesis
- How much does Total Synthesis cost?
- Total Synthesis is listed on Steam at 9.99 USD (current store price; Steam sales may reduce this temporarily).
- What games are most similar to Total Synthesis?
- Based on Steam play patterns and shared genres/tags, the games most often recommended alongside Total Synthesis are Last Shinobi, Epic Action Packs, Sushiamo.
- Who developed Total Synthesis?
- Total Synthesis was developed by Sinter Labs LLC.
imho.run ranks Steam game alternatives using a mix of collaborative filtering (ALS / iALS / EASE / LightGCN), content scoring over genres, categories, Steam tags, developers, and publishers, plus AI-extracted vibes mined from review text. The page above is generated in seed mode anchored on Total Synthesis.
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