Single-player games like Total Synthesis
Below are 9 single-player Steam games similar to Total Synthesis, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Total Synthesis page.
Ranked picks
- 1
Last Shinobi
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
Dive into a tactical roguelike where every decision counts. Build a unique strategy, unlock new skills and companions, and refine your synergies. Each level is a strategic puzzle to solve. No deck, minimal randomness, only strategic choices.
- 2
Epic Action Packs
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
Become a master of Deckscovery when you combine cards, build your Master Deck and defeat the Deck Master while avoiding elemental weaknesses!
- 3
Sushiamo
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
Sushiamo is a roguelike deck-builder where you make sushi to reach absurd scores. Discover unique ingredients, sauces, game-changing tools, and navigate the map to break the game with insane combos!
- 4
SURVIVAL ARCHIVE
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
In this world consumed by chaos, there is no savior. Only you and your cards—explore the vast world, encounter NPCs by chance, battle enemies, plant and harvest, and discover how to make tomorrow better.
- 5
Tic Card Toe
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
A Turn Based Strategy Roguelike with Deckbuilding elements that transforms Tic-Tac-Toe into a High-Stakes Combat Tournament!
- 6
Pokermancer
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
A roguelike deckbuilder where poker hands are scored on a grid, not played from a hand. Link neighboring cards across a 4x4 grid into pairs, straights and flushes, then slide, swap and delete cards to bypass hazards that block the paths you need.
- 7
Crystal Core
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
Crystal Core is a first-person roguelike deckbuilder where every card becomes an action in battle. Build your deck, choose your hero, and descend through the cursed Crystal Caves, battling monsters and growing stronger with every encounter. Can you survive the depths and destroy the Crystal Core?
- 8
Pelican Empyrean
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
A roguelike cooking card game about collecting magic artefacts to amplify your culinary powers! Share the magic of abundance by cooking delicious meals for all who come to Pelican's kitchen. Food is love!
- 9
Total Biochem
Single-player alternative to Total Synthesis — playable solo, no multiplayer required. Shares Strategy and Indie with Total Synthesis.
The complete biochemistry study app: 3,300+ practice items across 37 topics, a lesson for every topic, 550+ flashcards, and a mock exam builder — built for course exams and MCAT review. The bonus: a clinical mystery where you work the night shift on a metabolic service and read the labs yourself.