Single-player games like Mutazione
Below are 10 single-player Steam games similar to Mutazione, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Mutazione page.
Ranked picks
- 1

SEASON: A letter to the future
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
Leave home for the first time to collect memories before a mysterious cataclysm washes everything away. Ride, record, meet people, and unravel the strange world around you in this third-person meditative exploration game.
- 2

Sumire
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
One Day, One Life. Sumire is a magical narrative adventure about choices made, and dreams lost and found. Embark on a mysterious journey to help Sumire achieve her deepest wishes, before the day ends and the sky turns to twilight.
- 3

The Berlin Apartment
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
One apartment, many stories: Witness turning points in the lives of the inhabitants of an apartment in Berlin over the course of a whole century.
- 4

Behind the Frame: The Finest Scenery
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
Guide brush strokes and solve a variety of puzzles to help an aspiring artist complete her masterpiece amid her brusque neighbor’s gaze and his pesky cat. As her painting starts to take shape, uncover an emotional tale of chance and artistry revealed behind unrelated yet familiar moments.
- 5

Gone Home
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
June 7th, 1995. 1:15 AM. You arrive home after a year abroad. You expect your family to greet you, but the house is empty. Something's not right. Where is everyone? And what's happened here? Unravel the mystery for yourself in Gone Home, a story exploration game from The Fullbright Company.
- 6

The Cosmic Wheel Sisterhood
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
Immerse yourself in an enchanting narrative experience as Fortuna, a fortune-teller Witch condemned to exile on her asteroid home. Craft your own Tarot deck, regain your freedom, and shape the fate of the cosmic Witch society.
- 7

1000xRESIST
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
1000xRESIST is a thrilling sci-fi adventure. The year is unknown, and a disease spread by an alien invasion keeps you underground. You are Watcher. You dutifully fulfil your purpose in serving the ALLMOTHER, until the day you discover a shocking secret that changes everything.
- 8

Whispering Willows
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
Interact with the spirits of the dead, solve the puzzles of the mysterious mansion and help Elena find her missing father in the horror/adventure puzzle game: Whispering Willows.
- 9

Viridi
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie with Mutazione.
Nurture a small pot of succulents that grow in real time. Viridi is a safe haven, a place you can return to for a moment of peace and quiet whenever you need it.
- 10

Saltsea Chronicles
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
It begins with a kidnapped captain and a stolen ship. Where it leads next? That’s up to you… In this story-driven adventure game you will explore strange and wonderful communities, uncover a deep conspiracy, and chart a journey through twists and turns, difficulties and delights.