Single-player games like Mutazione
Below are 9 single-player Steam games similar to Mutazione, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Mutazione page.
Ranked picks
- 1

Brass
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
As the player, you take on the role of Brass, delivering letters and packages while interacting with the villagers. One day, a letter from his grandma sets Brass off on a new adventure. With relaxing, story-driven gameplay and adorable low-poly art, Brass offers a cozy and heartwarming experience.
- 2

ALTERITY EXPERIENCE
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
You are Anton Cornwell, a Californian farmer. Recently, your ranch house is prey to strange and unexplained phenomena. Invaded from all sides, you need to be reactive by using your mind to prevent any intrusions. Will you survive the eventful night ahead?
- 3

TR-49
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Adventure with Mutazione.
A World War II computer. An archive of lost books. A world-changing secret. Narrative deduction meets audio drama, from the creators of Overboard!, Heaven's Vault and A Highland Song.
- 4

Sumire
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
One Day, One Life. Sumire is a magical narrative adventure about choices made, and dreams lost and found. Embark on a mysterious journey to help Sumire achieve her deepest wishes, before the day ends and the sky turns to twilight.
- 5

Saltsea Chronicles
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
It begins with a kidnapped captain and a stolen ship. Where it leads next? That’s up to you… In this story-driven adventure game you will explore strange and wonderful communities, uncover a deep conspiracy, and chart a journey through twists and turns, difficulties and delights.
- 6

Whispering Willows
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
Interact with the spirits of the dead, solve the puzzles of the mysterious mansion and help Elena find her missing father in the horror/adventure puzzle game: Whispering Willows.
- 7

Scarlet Hollow
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
Your aunt’s dead, your cousin hates you, and you’re stuck in the dead-end town of Scarlet Hollow. Choose your path through a branching narrative so dense that you'll see less than 1/5 of the game on a single playthrough. You won't be able to save everyone. Good luck, and welcome home.
- 8

OXENFREE II: Lost Signals
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie and Adventure with Mutazione.
Five years after the events of OXENFREE, Riley returns to her hometown of Camena to investigate mysterious radio signals. What she finds is more than she bargained for.
- 9

Viridi
Single-player alternative to Mutazione — playable solo, no multiplayer required. Shares Indie with Mutazione.
Nurture a small pot of succulents that grow in real time. Viridi is a safe haven, a place you can return to for a moment of peace and quiet whenever you need it.