IMHO.

Single-player games like The Binding of Isaac

Below are 21 single-player Steam games similar to The Binding of Isaac, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like The Binding of Isaac page.

Ranked picks

  1. 1
    The Binding of Isaac: Rebirth — Steam game cover

    The Binding of Isaac: Rebirth

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action with The Binding of Isaac.

    The Binding of Isaac: Rebirth is a randomly generated action RPG shooter with heavy Rogue-like elements. Following Isaac on his journey players will find bizarre treasures that change Isaac’s form giving him super human abilities and enabling him to fight off droves of mysterious creatures, discover secrets and fight his way to safety.

    2014Action14.99 USDDeck VerifiedSingle-playerSimilar games →
  2. 2
    Our Darker Purpose — Steam game cover

    Our Darker Purpose

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Journey to the dark heart of the Edgewood Home for Lost Children in this fiendishly difficult action RPG!When her teacher stepped out of the classroom a month ago, Cordy never imagined he would be gone for good. Now her fellow students have turned on each other as the school descends into chaos.

    2014ActionIndieRPG14.99 USDSingle-playerSimilar games →
  3. 3
    Soulblight — Steam game cover

    Soulblight

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Soulblight is a dark, unforgiving, top-down action roguelike luring you to cross the thin line between good and evil. Embrace your flaws to survive a journey through an unforgiving Sanctuary. Gluttony, Lust, Cannibalism - how far are you willing to go?

    2018ActionIndieRPG14.99 USDDeck PlayableSingle-playerSimilar games →
  4. 4
    Enlightenment — Steam game cover

    Enlightenment

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    In Enlightenment, you play in a roguelike action-shooter with a fast-paced challenging journey deep into a underground complex called "the Ark". Players will be tested by large varieties of enemies in a procedurally-generated dungeon, and become stronger by learning from the inevitable deaths.

    2018ActionIndie11.99 USDSingle-playerSimilar games →
  5. 5
    Devil Slayer - Raksasi — Steam game cover

    Devil Slayer - Raksasi

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Devil Slayer - Raksasi is a top-down action game with procedurally generated dungeons, profound roguelike elements, and intuitive soul-like fighting. It's a fair and challenging game, dodging, timing, striking, you need to master them all to fight your way out of this cursed world.

    2021ActionIndieAdventure10.49 USDDeck VerifiedSingle-playerSimilar games →
  6. 6
    Teleglitch: Die More Edition — Steam game cover

    Teleglitch: Die More Edition

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    In a cold, dark future dominated by mega-corporations, a small lonely planet on the edge of habitable space is the site of a shadowy research facility specializing in necrotic tissue reactivation. You are a scientist who has suddenly awoken to the realization that you are the lone survivor.

    2013ActionIndie3.24 USDDeck PlayableSingle-playerSimilar games →
  7. 7
    Dunjungle — Steam game cover

    Dunjungle

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    A 2d action-packed roguelite about a monkey hero protecting the jungle from the rise of a corruptive power. Explore ever-changing dungeons, fight weird enemies and gear up with lots of weapons and relics you can combine for a new experience every run. Explore, fight, die, and repeat!

    2025ActionIndieAdventure14.99 USDDeck VerifiedSingle-playerSimilar games →
  8. 8
    Nuclear Throne — Steam game cover

    Nuclear Throne

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Nuclear Throne is a post-apocalyptic roguelike-like top-down shooter. Not 'the final hope of humanity' post-apocalyptic, but 'humanity is extinct and mutants and monsters now roam the world' post-apocalyptic. Can you reach the Nuclear Throne?

    2015ActionIndieRPG11.99 USDDeck VerifiedSingle-playerSimilar games →
  9. 9
    Enter the Gungeon — Steam game cover

    Enter the Gungeon

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Enter the Gungeon is a bullet hell dungeon crawler following a band of misfits seeking to shoot, loot, dodge roll and table-flip their way to personal absolution by reaching the legendary Gungeon’s ultimate treasure: the gun that can kill the past.

    2016ActionIndieAdventure14.99 USDDeck VerifiedSingle-playerSimilar games →
  10. 10
    Dead Cells — Steam game cover

    Dead Cells

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Dead Cells is a roguelite, metroidvania inspired, action-platformer. You'll explore a sprawling, ever-changing castle... assuming you’re able to fight your way past its keepers in 2D souls-lite combat. No checkpoints. Kill, die, learn, repeat.

    2018ActionIndieAdventure24.99 USDDeck VerifiedSingle-playerSimilar games →
  11. 11
    Risk of Rain 2 — Steam game cover

    Risk of Rain 2

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Escape a chaotic alien planet by fighting through hordes of frenzied monsters – with your friends, or on your own. Combine loot in surprising ways and master each character until you become the havoc you feared upon your first crash landing.

    2020ActionIndie24.99 USDDeck PlayableSingle-playerSimilar games →
  12. 12
    Hades — Steam game cover

    Hades

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Defy the god of the dead as you hack and slash out of the Underworld in this rogue-like dungeon crawler from the creators of Bastion, Transistor, and Pyre.

    2020ActionIndieRPG24.99 USDDeck VerifiedSingle-playerSimilar games →
  13. 13
    Brotato — Steam game cover

    Brotato

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Brotato is a top-down arena shooter roguelite where you play a potato wielding up to 6 weapons at a time to fight off hordes of aliens. Choose from a variety of traits and items to create unique builds and survive until help arrives.

    2023ActionIndieRPG4.99 USDDeck VerifiedSingle-playerSimilar games →
  14. 14
    Crypt of the NecroDancer — Steam game cover

    Crypt of the NecroDancer

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Crypt of the NecroDancer is an award winning hardcore roguelike rhythm game. Move to the music and deliver beatdowns to the beat! Groove to the epic Danny Baranowsky soundtrack, or select songs from your own MP3 collection!

    2015ActionIndieRPG2.99 USDDeck VerifiedSingle-playerSimilar games →
  15. 15
    Tiny Rogues — Steam game cover

    Tiny Rogues

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Tiny Rogues is a challenging fantasy rogue-lite bullet-hell dungeon crawler with rpg elements. Build a new unique character each run and fight one monster-infested room after another! Discover unique weapons, collect magical items and level up to become more and more powerful!

    2022ActionIndieAdventure9.99 USDDeck VerifiedSingle-playerSimilar games →
  16. 16
    Mewgenics — Steam game cover

    Mewgenics

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Indie and Adventure with The Binding of Isaac.

    Build the ultimate cat army through tactical breeding and send them into deep, challenging turn-based adventures. Draft abilities, collect items, and manipulate genetics across generations in this roguelike tactics game from the creators of The Binding of Isaac and The End is Nigh.

    2026StrategyIndieAdventure29.99 USDDeck VerifiedSingle-playerSimilar games →
  17. 17
    The Legend of Bum-Bo — Steam game cover

    The Legend of Bum-Bo

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Indie and Adventure with The Binding of Isaac.

    A puzzle based deck building rogue-like prequel to The Binding of Isaac... Made of cardboard!

    2019StrategyIndieAdventure14.99 USDDeck PlayableSingle-playerSimilar games →
  18. 18
    The End Is Nigh — Steam game cover

    The End Is Nigh

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    The End Is Nigh is a sprawling adventure platformer where you die a lot, but thats ok because you are probably already dead anyway.

    2017ActionIndieAdventure14.99 USDDeck VerifiedSingle-playerSimilar games →
  19. 19
    The Basement Collection — Steam game cover

    The Basement Collection

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Indie and Adventure with The Binding of Isaac.

    A collection of 9 award winning indie games from the creator of "Binding of isaac" and "Super Meat Boy"!

    2012StrategyIndieAdventure3.99 USDDeck PlayableSingle-playerSimilar games →
  20. 20
    Fingered — Steam game cover

    Fingered

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Indie with The Binding of Isaac.

    GUILTY! THEY ARE ALL GUILTY! FINGERED is a "whodunit" hyperrealisic police sim where you must finger the guilty and clean up this darn city using the descriptions of the local busy bodies. but everyone's perspective is different: one man's fat is another man's sexy! send him to the chair!!!

    2015IndieCasual1.87 USDDeck VerifiedSingle-playerSimilar games →
  21. 21
    Gish — Steam game cover

    Gish

    Single-player alternative to The Binding of Isaac — playable solo, no multiplayer required. Shares Action and Indie with The Binding of Isaac.

    Gish isn't your average hero. In fact, he's not your average anything...you see, Gish is a ball of tar. A Sunday stroll with his lady friend, Brea, goes awry when a shadowy figure emerges from an open manhole and pulls Brea below ground.

    2007ActionIndieAdventure9.99 USDSingle-playerSimilar games →