Single-player games like Cartridge Defense
Below are 10 single-player Steam games similar to Cartridge Defense, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Cartridge Defense page.
Ranked picks
- 1
Tower Tactics: Liberation
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
We fused deck-building roguelikes and tower defenses in a way never seen before - deploy your towers, collect valuable trinkets and cast powerful spells to defend yourself against the Salkoth!
- 2
Kemotaku
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
"Kemotaku" is a brand new roguelike card game mixed with puzzle, deck-building and tower-defence. Beat away attacking enemies and defend your town with a variety of animals!
- 3
Overdungeon
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
A completely new style real-time card battle "Overdungeon" Overdungeon combines rogue-like, tower defense and card games. More than 100 cards are Attack, Animal, Building, Spell, Trap, etc..Build your creative and crazy deck!
- 4
Zero Division
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
A roguelite deckbuilder crossed with a CCG, set in a dark cyberpunk world. You will lead a three-man squad against competing factions fighting among the ashes of a world-wide war. Each operator comes with a unique deck that can be customized and augmented.
- 5
System Crash
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
System Crash is a story-driven cyberpunk collectible card game inspired by Blade Runner and Neuromancer. When corporations own everything and the line between man and machine is blurred, your only option is to fight to survive!
- 6
Breach Wanderers
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
A fresh take on Roguelike Deckbuilders that lets you fine-tune your decks before each run to adapt your strategy on your way to victory. Over 1,200 cards to choose from, ten characters with their own set of unique skills, and dozens of items and missions to evolve your tactics.
- 7
Mythgard
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
Welcome to Mythgard, a fantasy cyberpunk CCG of heroes, gods, and mythical beasts. Master the unique lane and mana systems in your rise to the top or enjoy team play with a friend. New players can use the code WelcomeChallenger to get 20 free packs and more to start their journey.
- 8
Nitro Kid
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
Synthwave roguelike deckbuilder set in the neon 80's. Pick your agent. Build your deck. Hit card combos and fight through the floors of INFINITY tower. Featuring 30+ fresh Synthwave tracks by LudoWic, Tonebox and Jules Reves.
- 9
Slay the Spire
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Strategy and Indie with Cartridge Defense.
We fused card games and roguelikes together to make the best single player deckbuilder we could. Craft a unique deck, encounter bizarre creatures, discover relics of immense power, and Slay the Spire!
- 10
Kingdom Run VR
Single-player alternative to Cartridge Defense — playable solo, no multiplayer required. Shares Indie with Cartridge Defense.
Kingdom Run VR is an action-packed fitness game; explore trapped tombs, avoid dangers, collect gems and eliminate enemies!