Single-player games like The ER: Patient Typhon
Below are 13 single-player Steam games similar to The ER: Patient Typhon, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like The ER: Patient Typhon page.
Ranked picks
- 1

The Story of Henry Bishop
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Indie with The ER: Patient Typhon.
The story of Henry Bishop is a first-person psychological thriller, where the player will have to fight, guess riddles, immerse into a mystical plot and an incredible story.
- 2

The Evil Within 2
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Adventure with The ER: Patient Typhon.
Detective Sebastian Castellanos has lost everything, including his daughter, Lily. To save her, he must descend into the nightmarish world of STEM. Horrifying threats emerge from every corner, and he must rely on his wits to survive. For his one chance at redemption, the only way out is in.
- 3

Amnesia: The Dark Descent
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Indie with The ER: Patient Typhon.
Amnesia: The Dark Descent, a first person survival horror. A game about immersion, discovery and living through a nightmare. An experience that will chill you to the core.
- 4

Fragile
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Indie and Adventure with The ER: Patient Typhon.
Get pulled into the nightmares of reality as you play as an abducted girl from the ger district of Ulaanbaatar, Mongolia. Uncover a secret organization that deals in human trafficking and other horrendous activities. Try to escape from the scariest place on earth!
- 5

Mirror Forge
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Indie and Adventure with The ER: Patient Typhon.
Mirror Forge is a first-person psychological survival horror game. Roam between realities of fear, madness & machinery. Solve puzzles, explore an atmospheric world, survive horrifying entities.
- 6

The Beast Inside
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Indie with The ER: Patient Typhon.
The Beast Inside is a unique, gripping twist on thriller and survival horror. Immerse in the story of long-buried secrets, personal tragedies, and madness. Play as two protagonists bounded by dark heritage. Combat the enemies, solve riddles and experience real terror in the 3D-scanned environment.
- 7

Mouthwashing
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Indie and Adventure with The ER: Patient Typhon.
The five crew members of the Tulpar are stranded in the empty reaches of space, shrouded in perpetual sunset. God is not watching.
- 8

Remothered: Tormented Fathers
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Indie with The ER: Patient Typhon.
Remothered: Tormented Fathers is the pure and realistic survival horror videogame
- 9

Resident Evil
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Adventure with The ER: Patient Typhon.
The game that defined the survival-horror genre is back! Check out the remastered HD version of Resident Evil.
- 10

SILENT HILL 2
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Adventure with The ER: Patient Typhon.
Investigating a letter from his late wife, James returns to where they made so many memories - Silent Hill. What he finds is a ghost town, prowled by disturbing monsters and cloaked in deep fog. Confront the monsters, solve puzzles, and search for traces of your wife in this remake of SILENT HILL 2.
- 11

Anglerfish
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Indie with The ER: Patient Typhon.
The game only saves when you die. Every time you die, something changes. Every change is based on where and how you died. Go on an epic adventure only equipped with your trusted shotgun, your wit and your strong stomach for disturbing exploration. Can you survive a night at the bar, Anglerfish?
- 12

Security: The Horrible Nights
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Action and Indie with The ER: Patient Typhon.
Every time you die, a new story begins. You are the nighttime security guard at a hospital. Your job is to monitor the hospital and fix problems when they happen. Every night, a new horror tale will unfold. If you can survive enough nights, you will learn the truth behind all the horror!
- 13

Help! I am REALLY horny!
Single-player alternative to The ER: Patient Typhon — playable solo, no multiplayer required. Shares Indie and Adventure with The ER: Patient Typhon.
Help! I am REALLY horny! is a highly interactive adventure dating game where you color the tale along the way in unforeseeable ways through your choices and your dick slapping and tit swinging inputs.