Single-player games like ANNO: Mutationem
Below are 16 single-player Steam games similar to ANNO: Mutationem, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like ANNO: Mutationem page.
Ranked picks
- 1

Cyberpunk: Shadow of Ethereal City
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
Cyberpunk: Shadow of Ethereal City is a 2.5D hacker RPG. You will play as HC999, an experimental cyborg who lost contact with a major corporation. HC999 uses nanobots to hack into others' souls to manipulate the environment, persuade others, defeat opponents and explore the true nature of the city.
- 2

侵入:源代码
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
"Inception: source code" is a fun cyberpunk action game created with a new concept! The game is very difficult. The cute sister controlled by the player can rebound bullets and kill the enemy in the gorgeous light and shadow of the sword.
- 3

Frontier Hunter: Erza’s Wheel of Fortune
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
This is an anime-style Metroidvania game with an RPG progression system, numerous weapons for switching, and an emphasis on equipment building. It offers three switchable characters, smooth gameplay, impactful combat feedback, and anime-style story scenes.
- 4

Virtua Unlimited Project
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
Virtua Unlimited Project is a 2D pixel-art style ACT game featuring VTuber characters. With classical platformer gameplay, challenging combat, and retro game feelings, VUP presents you a surreal, virtual world in which you will play as Aizawa Kana to venture and seek the truth beneath.
- 5

Twilight Monk
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
Embark on a quest to recover the Three Rings of the Triskelion, as the last descendant of ancient Kung Fu warriors in Twilight Monk!. Experience a richly crafted Metroidvania, RPG, with intricately crafted dungeons, linked across a vast overworld spanning multiple continents.
- 6

F.I.S.T.: Forged In Shadow Torch
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
F.I.S.T.: Forged In Shadow Torch is a Metroidvania action game featuring exploration, intense combat and challenging platforming.
- 7

Yars Rising
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Adventure with ANNO: Mutationem.
From the renowned development studio WayForward Technologies, Inc. (Shantae, River City Girls, Advance Wars 1+2: Re-Boot Camp) comes Yars Rising, a 2D action adventure exploration of one of Atari’s richest, and best known classic titles.
- 8

REPLACED
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
Follow Reach, an AI trapped in a human body, as you expose the sinister secrets of Phoenix Corp. Set in an alternate 1980s America, experience a cinematic 2.5D adventure - a dark cyberpunk thriller blending atmospheric exploration with immersive, high-stakes action.
- 9

Medieval Dynasty
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
Hunt, survive, build and lead in the harsh Middle Ages: Create your own Medieval Dynasty and ensure its long-lasting prosperity or die trying! Play alone or team up with friends to enjoy the ultimate medieval experience.
- 10

RimWorld
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Indie with ANNO: Mutationem.
A sci-fi colony sim driven by an intelligent AI storyteller. Generates stories by simulating psychology, ecology, gunplay, melee combat, climate, biomes, diplomacy, interpersonal relationships, art, medicine, trade, and more.
- 11

VA-11 Hall-A: Cyberpunk Bartender Action
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Indie and Adventure with ANNO: Mutationem.
VA-11 HALL-A: Cyberpunk Bartender Action is a booze em' up about waifus, technology, and post-dystopia life.
- 12

SCP Foundation: ITTLG - Chapter 1
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and Indie with ANNO: Mutationem.
SCP Foundation: ITTLG Chapter 1 is a visual novel about, SCP-105 & SCP-105-B and her friendship with you. Trying to escape the foundation, in the end. They find out the dark truth behind their existence.
- 13

NieR:Automata™
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Action and RPG with ANNO: Mutationem.
NieR: Automata tells the story of androids 2B, 9S and A2 and their battle to reclaim the machine-driven dystopia overrun by powerful machines.
- 14

Foundation
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Indie with ANNO: Mutationem.
Foundation is a grid-less, laidback medieval city-building game with a focus on organic development, monument construction and resource management.
- 15

Stonehearth
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Indie with ANNO: Mutationem.
Pioneer a living world full of warmth, heroism, and mystery. Help a small group of settlers build a home for themselves in a forgotten land. Establish a food supply, build shelter, defend your people, monitor their moods, and find a way to grow and expand, facing challenges at every step.
- 16

Dwarf Fortress
Single-player alternative to ANNO: Mutationem — playable solo, no multiplayer required. Shares Indie with ANNO: Mutationem.
Build a fortress and try to help your dwarves survive against a deeply generated world. Keep your dwarves happy, grow their community and beware of digging too deeply. The deepest, most intricate simulation of a world that's ever been created.