IMHO.

Single-player games like The Last Disease Z

Below are 8 single-player Steam games similar to The Last Disease Z, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like The Last Disease Z page.

Ranked picks

  1. 1
    Zector 7 — Steam game cover

    Zector 7

    Single-player alternative to The Last Disease Z — playable solo, no multiplayer required. Shares Action and Indie with The Last Disease Z.

    Craft, Build and Fight alongside your friends across this deadly open-world. Use both modern day and sci-fi tech as you Loot, Harvest and Trade for resources, gear and vehicles in order to survive the wasteland.

    2024ActionStrategyIndie9.99 USDSingle-playerSimilar games →
  2. 2
    Future Fall — Steam game cover

    Future Fall

    Single-player alternative to The Last Disease Z — playable solo, no multiplayer required. Shares Action and Indie with The Last Disease Z.

    Immerse yourself in the multiplayer post-apocalyptic world of Future Fall. Survive in the exclusion zone, explore the world, collect artifacts, upgrade, fight for resources and lead your clan to victory! Crafting, PvP, PvE and dynamic events are waiting for you

    2027ActionIndieSimulationFreeSingle-playerSimilar games →
  3. 3
    7 Days to Die — Steam game cover

    7 Days to Die

    Single-player alternative to The Last Disease Z — playable solo, no multiplayer required. Shares Action and Indie with The Last Disease Z.

    7 Days to Die is an open-world game that is a unique combination of first-person shooter, survival horror, tower defense, and role-playing games. Play the definitive zombie survival sandbox RPG that came first. Navezgane awaits!

    2024ActionStrategyIndie44.99 USDDeck VerifiedSingle-playerSimilar games →
  4. 4
    Night of the Dead — Steam game cover

    Night of the Dead

    Single-player alternative to The Last Disease Z — playable solo, no multiplayer required. Shares Action and Indie with The Last Disease Z.

    'Night of the Dead' is an open-world game that combines elements of exploration, tower defense, survival, and crafting. Traverse a world dominated by zombies while collecting various resources and powerful equipment. Build a fortress to survive the hordes of zombies that swarm every night!

    2024ActionIndieAdventure29.99 USDDeck PlayableSingle-playerSimilar games →
  5. 5
    Zombie Survival Game Online — Steam game cover

    Zombie Survival Game Online

    Single-player alternative to The Last Disease Z — playable solo, no multiplayer required. Shares Action and Indie with The Last Disease Z.

    Zombie Survival Game Online is an open-world, post-apocalyptic, looter shooter. Craft, quest, explore, build, and fight for survival. Parkour up a mountainside, ramp a truck over a horde, and grab a gasmask to explore the sewers. Can you survive? Doubtful.

    2023ActionStrategyIndie3.99 USDDeck PlayableSingle-playerSimilar games →
  6. 6
    Infect: The Last Stand — Steam game cover

    Infect: The Last Stand

    Single-player alternative to The Last Disease Z — playable solo, no multiplayer required. Shares Action and Indie with The Last Disease Z.

    Experience brutal Hardcore PvPvE survival powered by Unreal Engine 5. Every decision matters, every step could be your last, and every sound you hear might be your final one. Do you have what it takes to survive the hunt?

    ActionIndieAdventureSingle-playerSimilar games →
  7. 7
    Afterinfection — Steam game cover

    Afterinfection

    Single-player alternative to The Last Disease Z — playable solo, no multiplayer required. Shares Action and Indie with The Last Disease Z.

    Afterinfection is a brand new zombie survival game designed in Unreal 4 and being developed by a small team from Thailand. After creating your survivor, you’ll start with nothing and have to make your way across a large island searching for food, water, weapons, and crafting supplies.

    2025ActionStrategyIndie8.99 USDSingle-playerSimilar games →
  8. 8
    DeadPoly — Steam game cover

    DeadPoly

    Single-player alternative to The Last Disease Z — playable solo, no multiplayer required. Shares Action and Indie with The Last Disease Z.

    DeadPoly is a polygon arcade zombie survival looter shooter with base building, crafting, scavenging, leveling, questing, and more, but your only goal is survival, everything else is optional.

    2022ActionIndieAdventure9.99 USDDeck PlayableSingle-playerSimilar games →