IMHO.

Single-player games like Mutagenic

Below are 12 single-player Steam games similar to Mutagenic, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.

Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Mutagenic page.

Ranked picks

  1. 1
    Tenfold — Steam game cover

    Tenfold

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and RPG with Mutagenic.

    Fast-paced dungeon combat, powerful spell synergies, deadly boss mechanics, and endless opportunities to master your fire magic.

    ActionRPGSingle-playerSimilar games →
  2. 2
    BPM Bitcrushed — Steam game cover

    BPM Bitcrushed

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and RPG with Mutagenic.

    BPM Bitcrushed: A retro roguelite rhythm shooter where every shot, dodge, and jump must sync to the beat. Battle through dungeons where enemies attack in time with the music. Find epic loot and even import your own songs to create a custom, rhythm-fuelled soundtrack for your destruction!

    ActionAdventureRPGSingle-playerSimilar games →
  3. 3
    Dredgers — Steam game cover

    Dredgers

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Indie and RPG with Mutagenic.

    Based on traditional rogue-likes, Dredgers is a real-time dungeon crawler where you can play as 30 different races, each having their own stats and skills. With the unique class system you can mix and match classes as you desire, anything from an Archer-Knight to a Berserker-Summoner-Priest is possible!

    2019IndieRPG11.99 USDDeck VerifiedSingle-playerSimilar games →
  4. 4
    Fight To The Death — Steam game cover

    Fight To The Death

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.

    Fight To The Death is a roguelite game where you enter an arena filled with hundreds or even thousands of monsters. Utilizing each character's unique skills, collecting powerful items, crafting your own playstyle, and striving to be the last one standing.

    2024ActionIndieRPG2.99 USDDeck PlayableSingle-playerSimilar games →
  5. 5
    FORCED SHOWDOWN — Steam game cover

    FORCED SHOWDOWN

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Strategy with Mutagenic.

    Deckbuilding empowers this challenging bullet hell adventure! Each character is a unique experience: Choose a deck of unlockable cards to boost you in new ways every battle - "My whirlwind shoots fireballs!?". Battle hordes of brutal foes to become a superstar in C-SAR’s ever-changing game show.

    2016ActionStrategyIndie19.99 USDSingle-playerSimilar games →
  6. 6
    Sharded World — Steam game cover

    Sharded World

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.

    Sharded World is a reversed bullet hell, rogue-lite, ARPG game combining simple gameplay and great rpg progression. Each level has its own unique features and challenges. Upgradable characters, weapons and orbs. Challenges, daily quests, and leaderboards. Fight, get stronger and defeat the Lich!

    2023ActionIndieAdventure4.99 USDDeck PlayableSingle-playerSimilar games →
  7. 7
    Rune Knights — Steam game cover

    Rune Knights

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.

    Rune Knights is a cooperative action RPG focused on customization, crafting, and combat. Customize your character's aesthetics, stats, gameplay, and gear as you battle through procedurally generated and hand-crafted levels with your allies.

    2020ActionIndieRPG19.99 USDSingle-playerSimilar games →
  8. 8
    Sun Down Survivors — Steam game cover

    Sun Down Survivors

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Strategy with Mutagenic.

    Sun Down is a roguelike survivors-type game with a twist. Between upgrading your abilities during and between runs, you can craft turrets, collect battle-ready pets, and buy store upgrades to survive hordes of enemies through four changing seasons.

    2023ActionStrategyIndie4.99 USDDeck PlayableSingle-playerSimilar games →
  9. 9
    Path of Exile — Steam game cover

    Path of Exile

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.

    You are an Exile, struggling to survive on the dark continent of Wraeclast, as you fight to earn power that will allow you to exact your revenge against those who wronged you. Path of Exile is an online Action RPG set in a dark fantasy world. The game is completely free and will never be pay-to-win.

    2013ActionIndieAdventureFreeDeck PlayableSingle-playerSimilar games →
  10. 10
    Striving for Light — Steam game cover

    Striving for Light

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.

    Blending deep Action RPG buildcrafting with roguelite action, Striving for Light lets you shape and customize an infinite skilltree. Hunt for powerful loot, craft and upgrade weapons to legendary power, slay hordes of enemies and challenging bosses in ever-changing dark worlds.

    2025ActionIndieAdventure12.59 USDDeck VerifiedSingle-playerSimilar games →
  11. 11
    Vampire Survivors — Steam game cover

    Vampire Survivors

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.

    Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!

    2022ActionIndieRPG4.99 USDDeck VerifiedSingle-playerSimilar games →
  12. 12
    Diablo® IV — Steam game cover

    Diablo® IV

    Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and RPG with Mutagenic.

    Join the fight for Sanctuary in Diablo® IV, the ultimate action RPG adventure. Experience the critically acclaimed campaign and new seasonal content.

    2023ActionAdventureMassively Multiplayer49.99 USDDeck VerifiedSingle-playerSimilar games →