Single-player games like Mutagenic
Below are 12 single-player Steam games similar to Mutagenic, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Mutagenic page.
Ranked picks
- 1

SULFUR
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
SULFUR is a modern old-school action-adventure: Outsmart enemies, find treasure, improve weapons, harness powers. Delve deeper, find answers, make it end.
- 2

FORCED SHOWDOWN
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Strategy with Mutagenic.
Deckbuilding empowers this challenging bullet hell adventure! Each character is a unique experience: Choose a deck of unlockable cards to boost you in new ways every battle - "My whirlwind shoots fireballs!?". Battle hordes of brutal foes to become a superstar in C-SAR’s ever-changing game show.
- 3

Ziggurat
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
Dungeon-Crawling First Person Shooting at its finest! Fast-paced combat! Dozens of perks, spells and enemies! Level ups! Random Dungeons! Traps! Badass bosses! Carrots!
- 4

Machick
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
Defeat the heavily armed army of anti-magic toads and free the forest from destruction. Machick is a casual game where you craft your own wands, vanquish enemies, collect XP, and choose upgrades to go further on the journey.
- 5

Halls of Torment
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
Slay hordes of terrifying monsters in this horde survival roguelite. Descend into the Halls of Torment where the Lords of the underworld await you. Treasures, magical trinkets, and a growing cast of heroes will grant you the power to vanquish these horrors from beyond. How long can you survive?
- 6

Last Epoch
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
Uncover the Past, Reforge the Future. Ascend into one of 15 mastery classes and explore dangerous dungeons, hunt epic loot, craft legendary weapons, and wield the power of over a hundred transformative skill trees. Last Epoch is being developed by a team of passionate Action RPG enthusiasts.
- 7

Arboria
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
Fight, die, and fight again in this dark fantasy trollz-like roguelite. As a Yotun troll warrior, descend into the ever-changing, creepy dungeons of Durnar. Use a variety of Symbiotic Weapons and Bio-Mutations to slay enemies and heal The Father Tree.
- 8

Bioweaver
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Strategy and Indie with Mutagenic.
Bioweaver is an RPG game with the main content of treasure hunting and character building. You can use basic programming logic to deeply customize your skill sets, and you can also create organs with different attributes and functions with the special crafting system.
- 9

Path of Exile
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
You are an Exile, struggling to survive on the dark continent of Wraeclast, as you fight to earn power that will allow you to exact your revenge against those who wronged you. Path of Exile is an online Action RPG set in a dark fantasy world. The game is completely free and will never be pay-to-win.
- 10

Striving for Light
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
Blending deep Action RPG buildcrafting with roguelite action, Striving for Light lets you shape and customize an infinite skilltree. Hunt for powerful loot, craft and upgrade weapons to legendary power, slay hordes of enemies and challenging bosses in ever-changing dark worlds.
- 11

Vampire Survivors
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and Indie with Mutagenic.
Mow down thousands of night creatures and survive until dawn! Vampire Survivors is a gothic horror casual game with rogue-lite elements, where your choices can allow you to quickly snowball against the hundreds of monsters that get thrown at you. Be the bullet hell!
- 12

Diablo® IV
Single-player alternative to Mutagenic — playable solo, no multiplayer required. Shares Action and RPG with Mutagenic.
Join the fight for Sanctuary in Diablo® IV, the ultimate action RPG adventure. Experience the critically acclaimed campaign and new seasonal content.