Single-player games like Plague: London 1665
Below are 12 single-player Steam games similar to Plague: London 1665, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Plague: London 1665 page.
Ranked picks
- 1

Road to Empress I
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Indie and Adventure with Plague: London 1665.
You've never played a game like this before. Road to Empress I is a cinematic palace adventure where your choices decide everyone's fate. Tackle multiple story branches and a high mortality rate with charm, wisdom and courage? First...survive.
- 2

Dead in Antares
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Indie and Adventure with Plague: London 1665.
Dead in Antares is a turn-based survival management game with RPG elements, set on an alien planet. Lead a crew of survivors sent on a mission to save humanity. Manage their needs, strengthen their teamwork, and explore this mysterious world to find a way back home.
- 3

The Hungry Lamb: Traveling in the Late Ming Dynasty
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Indie and Adventure with Plague: London 1665.
He is a bandit who sells lives. She is a mute girl seeking revenge. In a famine-ravaged ancient China, a ruthless trafficker escorts four girls to a demon's feast. But when a deadly secret is revealed, a cold transaction turns into a journey of redemption. A dark visual novel about an unlikely bond.
- 4

Pathologic 3
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Indie and Adventure with Plague: London 1665.
In this psychological horror game, you are a doctor with only 12 days to save a town from a mysterious plague. Make ruthless decisions and diagnose with precision. Shape the town's future and rewrite the past. Hold yourself together while it all falls apart.
- 5

CONSCRIPT: Director’s Cut
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Indie and Adventure with Plague: London 1665.
During the First World War, a lone French soldier must navigate twisted trenches, scavenge for limited supplies and solve complex puzzles—all whilst fighting for survival in the midst of mankind’s most brutal and horrifying conflict. CONSCRIPT is a new historical take on classic survival horror.
- 6

Beholder
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Indie and Adventure with Plague: London 1665.
You’re a state-installed landlord in a totalitarian country. Place listening devices, steal and sneak into your tenants’ apartments. Use what you uncovered to report anyone capable of plotting against the state. You MUST! But WILL you?
- 7

Anno 117: Pax Romana
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Simulation with Plague: London 1665.
Shape the Roman Empire in this genre-defining strategic builder game. Build cities while expanding your influence through Roman provinces. Govern using your economic prowess, diplomatic skills, or military might.
- 8

Help Will Come Tomorrow
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Adventure and Simulation with Plague: London 1665.
In an uninhabitable Siberian wilderness, in a wake of October Revolution, a group of passengers survives the mysterious catastrophe of Trans-Siberian railway train. They must endure in a harsh ice-clad climate until rescue arrives. Facing many dangers, their own weaknesses and, their own prejudice.
- 9

Pathologic 2
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Indie and Adventure with Plague: London 1665.
Pathologic 2 is a groundbreaking open-world horror RPG. Resist the plague. Make medicine. Heal people. Perform an autopsy. Trade to get what you need. Fight and kill if necessary. Survive. Struggle with an outbreak in a secluded rural town that is rapidly turning into hell.
- 10

Urban Tale
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Indie and Adventure with Plague: London 1665.
Urban Tale is a realistic, vibrant and unique RPG that will allow you to fulfil your dreams, and pursue your most wanted goals in life. You start from scratch, having nothing in the city where you can meet a lot of people, that can help you throughout your adventure. Your goal is to succeed in life.
- 11

Rising Mist
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required. Shares Adventure and Simulation with Plague: London 1665.
Rising Mist is a story driven adventure set in the fantasy land of Occoterra where dark magic and evil forces have descended upon. To oppose the tyranny one must gain an alliance of the seven cities. Develop skills and trades, skilfully navigate between the intrigues of allies and enemies.
- 12

Doggo Estates
Single-player alternative to Plague: London 1665 — playable solo, no multiplayer required.
Doggo Estates is a single and multiplayer third-person action game in which a dog has everything he needs to become a real estate mogul: his warm liquid gold! Compete with other neighborhood dogs and pee on as many houses as you can before they do.