Single-player games like Vaccine Rebirth
Below are 11 single-player Steam games similar to Vaccine Rebirth, ranked by player overlap. Every pick carries Steam's Single-player category, so multiplayer-only titles or always-online games don't sneak in. imho.run pulls the category data from Steam directly — Single-player here matches what the store labels.
Want the full alternatives list (paid + free + Steam Deck + cheaper picks)? See the parent games like Vaccine Rebirth page.
Ranked picks
- 1
The Henchmen
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action and Indie with Vaccine Rebirth.
Relive the ‘90s crime sandbox alone, or with a partner by your side. Prepare for a head on collision of the classic and the contemporary in The Henchmen - a chaotic, co-operative crime thriller.
- 2
Only Out
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Indie with Vaccine Rebirth.
“Only Out” is a cooperative survival game for two players. Set in a post-apocalyptic wasteland, you and your partner must navigate a desolate village plagued by scarcity and danger. Trust each other, strategize together, face the relentless zombie threat, and uncover the only path to survival.
- 3
Outer Terror
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action and Indie with Vaccine Rebirth.
DON’T DIE as you assemble a ridiculous arsenal of weapons and desperately hold out against massive hordes of creatures pulled from a variety of classic horror genres reminiscent of 80s and 90s Golden Age comics and B-movies in this stylish action-packed arcade roguelite.
- 4
Vaccine Rebirth VR
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action and Indie with Vaccine Rebirth.
Enter once again into the world of Survival Horror, this time in VR
- 5
Waking Knightmare
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action with Vaccine Rebirth.
Become a Dream Walker in this high Adrenaline Knightmare! Push yourself to the limits on Single Player for a high score or challenge your friends in a battle with your Knightmares on your side. The choice is yours...
- 6
Super Woden GP 2
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Indie with Vaccine Rebirth.
Super Woden GP 2 is a love letter to the world of motor sports, offering a unique experience. Arcade-style isometric racing meets unrivaled campaign depth and a huge variety of vehicles to buy, sell and unlock.
- 7
Resident Evil 6
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action with Vaccine Rebirth.
Blending action and survival horror, Resident Evil 6 promises to be the dramatic horror experience of 2013.
- 8
Outbreak
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action and Indie with Vaccine Rebirth.
Race against the clock and battle the undead in this co-op survival horror nightmare.
- 9
FreezeME
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action and Indie with Vaccine Rebirth.
FreezeME is a A 3D platformer in the style of the 90s-era but wait there is a twist! The main character “R” has one special tool – a camera around her neck. This camera allows her to literally freeze the objects she photographs.
- 10
Innocence Island
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action and Indie with Vaccine Rebirth.
Legend has it that the three rays of light in the sky are emitted by a prism that grants happiness to the one who obtains it. You never believed in that, but it is your last resort...
- 11
Spy Drops
Single-player alternative to Vaccine Rebirth — playable solo, no multiplayer required. Shares Action and Indie with Vaccine Rebirth.
Inspired by stealth action from the 90’s, undertake a series of covert ops to save the world from a global terrorist threat. Experience PS generation, 3D stealth action updated with modern effects, randomly generated levels, modern equipment, and head-to-head local multiplayer.